Advancements, Challenges, and Future Directions in Tackling Glioblastoma Resistance to Small Kinase Inhibitors

por Fabro, Federica, Lamfers, Martine L. M., Leenstra, Sieger
Publicado 2022

The Multifaceted Role of Macrophages in Oncolytic Virotherapy

por Hofman, Laura, Lawler, Sean E., Lamfers, Martine L. M.
Publicado 2021

Personalizing Oncolytic Virotherapy for Glioblastoma: In Search of Biomarkers for Response

por Stavrakaki, Eftychia, Dirven, Clemens M. F., Lamfers, Martine L. M.
Publicado 2021

Drug Repurposing, a Fast-Track Approach to Develop Effective Treatments for Glioblastoma

por Ntafoulis, Ioannis, Koolen, Stijn L. W., Leenstra, Sieger, Lamfers, Martine L. M.
Publicado 2022

Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM

por Juric, Viktorija, Düssmann, Heiko, Lamfers, Martine L. M., Prehn, Jochen H. M., Rehm, Markus, Murphy, Brona M.
Publicado 2021

Effects of the IDH1 R132H Mutation on the Energy Metabolism: A Comparison between Tissue and Corresponding Primary Glioma Cell Cultures

por Dekker, Lennard J. M., Verheul, Cassandra, Wensveen, Nicky, Leenders, William, Lamfers, Martine L. M., Leenstra, Sieger, Luider, Theo M.
Publicado 2022

Novel kinome profiling technology reveals drug treatment is patient and 2D/3D model dependent in glioblastoma

por Fabro, Federica, Kannegieter, Nynke M., de Graaf, Erik L., Queiroz, Karla, Lamfers, Martine L. M., Ressa, Anna, Leenstra, Sieger
Publicado 2022

Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells

por van den Hengel, Sanne K, de Vrij, Jeroen, Uil, Taco G, Lamfers, Martine L, Sillevis Smitt, Peter AE, Hoeben, Rob C
Publicado 2011

Anatomical Differences Determine Distribution of Adenovirus after Convection-Enhanced Delivery to the Rat Brain

por Idema, Sander, Caretti, Viola, Lamfers, Martine L. M., van Beusechem, Victor W., Noske, David P., Vandertop, W. Peter, Dirven, Clemens M. F.
Publicado 2011

Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist

por Boccellato, Chiara, Kolbe, Emily, Peters, Nathalie, Juric, Viktorija, Fullstone, Gavin, Verreault, Maïté, Idbaih, Ahmed, Lamfers, Martine L. M., Murphy, Brona M., Rehm, Markus
Publicado 2021

Nonhuman Primate Adenoviruses of the Human Adenovirus B Species Are Potent and Broadly Acting Oncolytic Vector Candidates

por Bots, Selas T.F., Kemp, Vera, Cramer, Steve J., van den Wollenberg, Diana J.M., Hornsveld, Marten, Lamfers, Martine L.M., van der Pluijm, Gabri, Hoeben, Rob C.
Publicado 2022

Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation

por Juric, Viktorija, Hudson, Lance, Fay, Joanna, Richards, Cathy E., Jahns, Hanne, Verreault, Maïté, Bielle, Franck, Idbaih, Ahmed, Lamfers, Martine L. M., Hopkins, Ann M., Rehm, Markus, Murphy, Brona M.
Publicado 2021

Locally-Delivered T-Cell-Derived Cellular Vehicles Efficiently Track and Deliver Adenovirus Delta24-RGD to Infiltrating Glioma

por Balvers, Rutger K., Belcaid, Zineb, van den Hengel, Sanne K., Kloezeman, Jenneke, de Vrij, Jeroen, Wakimoto, Hiroaki, Hoeben, Rob C., Debets, Reno, Leenstra, Sieger, Dirven, Clemens, Lamfers, Martine L.M.
Publicado 2014

The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells

por Berghauser Pont, Lotte M.E., Kleijn, Anne, Kloezeman, Jenneke J., van den Bossche, Wouter, Kaufmann, Johanna K., de Vrij, Jeroen, Leenstra, Sieger, Dirven, Clemens M.F., Lamfers, Martine L.M.
Publicado 2015

IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis

por Gao, Ya, de Wit, Maurice, Struys, Eduard A., van der Linde, Herma C. Z., Salomons, Gajja S., Lamfers, Martine L. M., Willemsen, Rob, Sillevis Smitt, Peter A. E., French, Pim J.
Publicado 2018

The Bcl-2 inhibitor Obatoclax overcomes resistance to histone deacetylase inhibitors SAHA and LBH589 as radiosensitizers in patient-derived glioblastoma stem-like cells

por Berghauser Pont, Lotte M.E., Spoor, Jochem K.H., Venkatesan, Subramanian, Swagemakers, Sigrid, Kloezeman, Jenneke J., Dirven, Clemens M.F., van der Spek, Peter J., Lamfers, Martine L.M., Leenstra, Sieger
Publicado 2014

Delta-24-RGD Oncolytic Adenovirus Elicits Anti-Glioma Immunity in an Immunocompetent Mouse Model

por Jiang, Hong, Clise-Dwyer, Karen, Ruisaard, Kathryn E., Fan, Xuejun, Tian, Weihua, Gumin, Joy, Lamfers, Martine L., Kleijn, Anne, Lang, Frederick F., Yung, Wai-Kwan Alfred, Vence, Luis M., Gomez-Manzano, Candelaria, Fueyo, Juan
Publicado 2014

The Sequence of Delta24-RGD and TMZ Administration in Malignant Glioma Affects the Role of CD8(+)T Cell Anti-tumor Activity

por Kleijn, Anne, van den Bossche, Wouter, Haefner, Erik S., Belcaid, Zineb, Burghoorn-Maas, Chantal, Kloezeman, Jenneke J., Pas, Suzan D., Leenstra, Sieger, Debets, Reno, de Vrij, Jeroen, Dirven, Clemens M.F., Lamfers, Martine L.M.
Publicado 2017

THER-02. Pediatric brain tumor cultures reveal differential susceptibility to four oncolytic viruses

por Vazaios, Konstantinos, Stavrakaki, Eftychia, Vogelezang, Lisette, van den Hoogen, Bernadette, Hoeben, Rob C, Chiocca, Antonio E, Goins, William F, Hulleman, Esther, Straetemans, Trudy, Calkoen, Friso G J, van der Lugt, Jasper, Lamfers, Martine L M
Publicado 2022

Low-dose oncolytic adenovirus therapy overcomes tumor-induced immune suppression and sensitizes intracranial gliomas to anti-PD-1 therapy

por Belcaid, Zineb, Berrevoets, Cor, Choi, John, van Beelen, Edward, Stavrakaki, Eftychia, Pierson, Tessa, Kloezeman, Jenneke, Routkevitch, Denis, van der Kaaij, Mariëlle, van der Ploeg, Alicia, Mathios, Dimitrios, Sleijfer, Stefan, Dirven, Clemens, Lim, Michael, Debets, Reno, Lamfers, Martine L M
Publicado 2020