Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein–RNA Interaction of LIN28 and Let-7

por Borgelt, Lydia, Li, Fu, Hommen, Pascal, Lampe, Philipp, Hwang, Jimin, Goebel, Georg L., Sievers, Sonja, Wu, Peng
Publicado 2021

Cell‐Based Identification of New IDO1 Modulator Chemotypes

por Hennes, Elisabeth, Lampe, Philipp, Dötsch, Lara, Bruning, Nora, Pulvermacher, Lisa‐Marie, Sievers, Sonja, Ziegler, Slava, Waldmann, Herbert
Publicado 2021

Chemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy

por Poláchová, Edita, Bach, Kathrin, Heuten, Elena, Stanchev, Stancho, Tichá, Anežka, Lampe, Philipp, Majer, Pavel, Langer, Thomas, Lemberg, Marius K., Stříšovský, Kvido
Publicado 2022

Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype

por Xue, Gang, Xie, Jianing, Hinterndorfer, Matthias, Cigler, Marko, Dötsch, Lara, Imrichova, Hana, Lampe, Philipp, Cheng, Xiufen, Adariani, Soheila Rezaei, Winter, Georg E., Waldmann, Herbert
Publicado 2023