Mycobacterium tuberculosis arrests host cycle at the G(1)/S transition to establish long term infection

por Cumming, Bridgette M., Rahman, Md. Aejazur, Lamprecht, Dirk A., Rohde, Kyle H., Saini, Vikram, Adamson, John H., Russell, David G., Steyn, Adrie J. C.
Publicado 2017

Correction: Mycobacterium tuberculosis arrests host cycle at the G(1)/S transition to establish long term infection

por Cumming, Bridgette M., Rahman, Md. Aejazur, Lamprecht, Dirk A., Rohde, Kyle H., Saini, Vikram, Adamson, John H., Russell, David G., Steyn, Adrie J. C.
Publicado 2017

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

por Lamprecht, Dirk A., Finin, Peter M., Rahman, Md. Aejazur, Cumming, Bridgette M., Russell, Shannon L., Jonnala, Surendranadha R., Adamson, John H., Steyn, Adrie J. C.
Publicado 2016

Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis

por Foo, Caroline S., Lupien, Andréanne, Kienle, Maryline, Vocat, Anthony, Benjak, Andrej, Sommer, Raphael, Lamprecht, Dirk A., Steyn, Adrie J. C., Pethe, Kevin, Piton, Jérémie, Altmann, Karl-Heinz, Cole, Stewart T.
Publicado 2018

Compromised Metabolic Reprogramming Is an Early Indicator of CD8(+) T Cell Dysfunction during Chronic Mycobacterium tuberculosis Infection

por Russell, Shannon L., Lamprecht, Dirk A., Mandizvo, Tawanda, Jones, Terrence T., Naidoo, Vanessa, Addicott, Kelvin W., Moodley, Chivonne, Ngcobo, Bongani, Crossman, David K., Wells, Gordon, Steyn, Adrie J.C.
Publicado 2019

New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis

por Lupien, Andréanne, Foo, Caroline Shi-Yan, Savina, Svetlana, Vocat, Anthony, Piton, Jérémie, Monakhova, Natalia, Benjak, Andrej, Lamprecht, Dirk A., Steyn, Adrie J. C., Pethe, Kevin, Makarov, Vadim A., Cole, Stewart T.
Publicado 2020

Mycobacterium tuberculosis H(2)S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility

por Kunota, Tafara T. R., Rahman, Md. Aejazur, Truebody, Barry E., Mackenzie, Jared S., Saini, Vikram, Lamprecht, Dirk A., Adamson, John H., Sevalkar, Ritesh R., Lancaster, Jack R., Berney, Michael, Glasgow, Joel N., Steyn, Adrie J. C.
Publicado 2021

Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis

por Mackenzie, Jared S., Lamprecht, Dirk A., Asmal, Rukaya, Adamson, John H., Borah, Khushboo, Beste, Dany J. V., Lee, Bei Shi, Pethe, Kevin, Rousseau, Simon, Krieger, Inna, Sacchettini, James C., Glasgow, Joel N., Steyn, Adrie J. C.
Publicado 2020

Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

por Saini, Vikram, Chinta, Krishna C., Reddy, Vineel P., Glasgow, Joel N., Stein, Asaf, Lamprecht, Dirk A., Rahman, Md. Aejazur, Mackenzie, Jared S., Truebody, Barry E., Adamson, John H., Kunota, Tafara T. R., Bailey, Shannon M., Moellering, Douglas R., Lancaster, Jack R., Steyn, Adrie J. C.
Publicado 2020

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribu...

por Murugesan, Dinakaran, Ray, Peter C., Bayliss, Tracy, Prosser, Gareth A., Harrison, Justin R., Green, Kirsteen, Soares de Melo, Candice, Feng, Tzu-Shean, Street, Leslie J., Chibale, Kelly, Warner, Digby F., Mizrahi, Valerie, Epemolu, Ola, Scullion, Paul, Ellis, Lucy, Riley, Jennifer, Shishikura, Yoko, Ferguson, Liam, Osuna-Cabello, Maria, Read, Kevin D., Green, Simon R., Lamprecht, Dirk A., Finin, Peter M., Steyn, Adrie J. C., Ioerger, Thomas R., Sacchettini, Jim, Rhee, Kyu Y., Arora, Kriti, Barry, Clifton E., Wyatt, Paul G., Boshoff, Helena I. M.
Publicado 2018