Down syndrome: searching for the genetic culprits

por Lana-Elola, Eva, Watson-Scales, Sheona D., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J.
Publicado 2011

Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse

por Dunlevy, Louisa, Bennett, Mike, Slender, Amy, Lana-Elola, Eva, Tybulewicz, Victor L., Fisher, Elizabeth M.C., Mohun, Timothy
Publicado 2010

Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel

por Lana-Elola, Eva, Watson-Scales, Sheona, Slender, Amy, Gibbins, Dorota, Martineau, Alexandrine, Douglas, Charlotte, Mohun, Timothy, Fisher, Elizabeth MC, Tybulewicz, Victor LJ
Publicado 2016

Correction: Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel

por Lana-Elola, Eva, Watson-Scales, Sheona, Slender, Amy, Gibbins, Dorota, Martineau, Alexandrine, Douglas, Charlotte, Mohun, Timothy, Fisher, Elizabeth MC, Tybulewicz, Victor LJ
Publicado 2020

Alterations to Dendritic Spine Morphology, but Not Dendrite Patterning, of Cortical Projection Neurons in Tc1 and Ts1Rhr Mouse Models of Down Syndrome

por Haas, Matilda A., Bell, Donald, Slender, Amy, Lana-Elola, Eva, Watson-Scales, Sheona, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Guillemot, François
Publicado 2013

Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome

por Thomas, Jared R., LaCombe, Jonathan, Long, Rachel, Lana-Elola, Eva, Watson-Scales, Sheona, Wallace, Joseph M., Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Roper, Randall J.
Publicado 2020

Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes

por Redhead, Yushi, Gibbins, Dorota, Lana-Elola, Eva, Watson-Scales, Sheona, Dobson, Lisa, Krause, Matthias, Liu, Karen J., Fisher, Elizabeth M. C., Green, Jeremy B. A., Tybulewicz, Victor L. J.
Publicado 2023

Gene expression dysregulation domains are not a specific feature of Down syndrome

por Ahlfors, Helena, Anyanwu, Nneka, Pakanavicius, Edvinas, Dinischiotu, Natalia, Lana-Elola, Eva, Watson-Scales, Sheona, Tosh, Justin, Wiseman, Frances, Briscoe, James, Page, Karen, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J.
Publicado 2019

Genetic dissection of triplicated chromosome 21 orthologs yields varying skeletal traits in Down syndrome model mice

por Sloan, Kourtney, Thomas, Jared, Blackwell, Matthew, Voisard, Deanna, Lana-Elola, Eva, Watson-Scales, Sheona, Roper, Daniel L., Wallace, Joseph M., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Roper, Randall J.
Publicado 2023

Aging rather than aneuploidy affects monoamine neurotransmitters in brain regions of Down syndrome mouse models

por Dekker, Alain D., Vermeiren, Yannick, Albac, Christelle, Lana-Elola, Eva, Watson-Scales, Sheona, Gibbins, Dorota, Aerts, Tony, Van Dam, Debby, Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Potier, Marie-Claude, De Deyn, Peter P.
Publicado 2017

Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration

por Watson-Scales, Sheona, Kalmar, Bernadett, Lana-Elola, Eva, Gibbins, Dorota, La Russa, Federica, Wiseman, Frances, Williamson, Matthew, Saccon, Rachele, Slender, Amy, Olerinyova, Anna, Mahmood, Radma, Nye, Emma, Cater, Heather, Wells, Sara, Yu, Y. Eugene, Bennett, David L. H., Greensmith, Linda, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J.
Publicado 2018

Maternal iron deficiency perturbs embryonic cardiovascular development in mice

por Kalisch-Smith, Jacinta I., Ved, Nikita, Szumska, Dorota, Munro, Jacob, Troup, Michael, Harris, Shelley E., Rodriguez-Caro, Helena, Jacquemot, Aimée, Miller, Jack J., Stuart, Eleanor M., Wolna, Magda, Hardman, Emily, Prin, Fabrice, Lana-Elola, Eva, Aoidi, Rifdat, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Mohun, Timothy J., Lakhal-Littleton, Samira, De Val, Sarah, Giannoulatou, Eleni, Sparrow, Duncan B.
Publicado 2021

Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes

por Lana-Elola, Eva, Cater, Heather, Watson-Scales, Sheona, Greenaway, Simon, Müller-Winkler, Jennifer, Gibbins, Dorota, Nemes, Mihaela, Slender, Amy, Hough, Tertius, Keskivali-Bond, Piia, Scudamore, Cheryl L., Herbert, Eleanor, Banks, Gareth T., Mobbs, Helene, Canonica, Tara, Tosh, Justin, Noy, Suzanna, Llorian, Miriam, Nolan, Patrick M., Griffin, Julian L., Good, Mark, Simon, Michelle, Mallon, Ann-Marie, Wells, Sara, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J.
Publicado 2021