Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics

por Landau, Dan A, Wu, Catherine J
Publicado 2013

In vivo activation of transferred regulatory T cells specific for third‐party exogenous antigen controls GVH disease in mice

por Martin, Gaëlle H., Grégoire, Sylvie, Landau, Dan A., Pilon, Caroline, Grinberg‐Bleyer, Yenkel, Charlotte, Frédéric, Mège, Jean‐Pierre, Chatenoud, Lucienne, Salomon, Benoît L., Cohen, José L.
Publicado 2013

m(6)A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment

por Cheng, Yuanming, Luo, Hanzhi, Izzo, Franco, Pickering, Brian F., Nguyen, Diu, Myers, Robert, Schurer, Alexandra, Gourkanti, Saroj, Brϋning, Jens C., Vu, Ly P., Jaffrey, Samie R., Landau, Dan A., Kharas, Michael G.
Publicado 2019

Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus

por Odell, Shannon C., Taki, Faten, Klein, Shifra Liba, Chen, Rosa J., Levine, Olivia B., Skelly, Mary Jane, Nabila, Anika, Brindley, Elizabeth, Toth, Judit Gal, Dündar, Friederike, Sheridan, Caroline K., Fetcho, Robert N., Alonso, Alicia, Liston, Conor, Landau, Dan A., Pleil, Kristen E., Toth, Miklos
Publicado 2020

The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy

por Landau, Dan A., Sun, Clare, Rosebrock, Daniel, Herman, Sarah E. M., Fein, Joshua, Sivina, Mariela, Underbayev, Chingiz, Liu, Delong, Hoellenriegel, Julia, Ravichandran, Sarangan, Farooqui, Mohammed Z. H., Zhang, Wandi, Cibulskis, Carrie, Zviran, Asaf, Neuberg, Donna S., Livitz, Dimitri, Bozic, Ivana, Leshchiner, Ignaty, Getz, Gad, Burger, Jan A., Wiestner, Adrian, Wu, Catherine J.
Publicado 2017

Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization

por Ben-Chetrit, Nir, Niu, Xiang, Sotelo, Jesus, Swett, Ariel D., Rajasekhar, Vinagolu K., Jiao, Maria S., Stewart, Caitlin M., Bhardwaj, Priya, Kottapalli, Sanjay, Ganesan, Saravanan, Loyher, Pierre-Louis, Potenski, Catherine, Hannuna, Assaf, Brown, Kristy A., Iyengar, Neil M., Giri, Dilip D., Lowe, Scott W., Healey, John H., Geissmann, Frederic, Sagi, Irit, Joyce, Johanna A., Landau, Dan A.
Publicado 2023

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL

por Pastore, Alessandro, Gaiti, Federico, Lu, Sydney X., Brand, Ryan M., Kulm, Scott, Chaligne, Ronan, Gu, Hongcang, Huang, Kevin Y., Stamenova, Elena K., Béguelin, Wendy, Jiang, Yanwen, Schulman, Rafael C., Kim, Kyu-Tae, Alonso, Alicia, Allan, John N., Furman, Richard R., Gnirke, Andreas, Wu, Catherine J., Melnick, Ari M., Meissner, Alexander, Bernstein, Bradley E., Abdel-Wahab, Omar, Landau, Dan A.
Publicado 2019

Genotyping of Transcriptomes links somatic mutations and cell identity

por Nam, Anna S., Kim, Kyu-Tae, Chaligne, Ronan, Izzo, Franco, Ang, Chelston, Taylor, Justin, Myers, Robert M., Abu-Zeinah, Ghaith, Brand, Ryan, Omans, Nathaniel D., Alonso, Alicia, Sheridan, Caroline, Mariani, Marisa, Dai, Xiaoguang, Harrington, Eoghan, Pastore, Alessandro, Cubillos-Ruiz, Juan R., Tam, Wayne, Hoffman, Ronald, Rabadan, Raul, Scandura, Joseph M., Abdel-Wahab, Omar, Smibert, Peter, Landau, Dan A.
Publicado 2019

DNA methylation disruption reshapes the hematopoietic differentiation landscape

por Izzo, Franco, Lee, Stanley C., Poran, Asaf, Chaligne, Ronan, Gaiti, Federico, Gross, Baptiste, Murali, Rekha R., Deochand, Sunil D., Ang, Chelston, Jones, Philippa Wyndham, Nam, Anna S., Kim, Kyu-Tae, Kothen-Hill, Steven, Schulman, Rafael C., Ki, Michelle, Lhoumaud, Priscillia, Skok, Jane A., Viny, Aaron D., Levine, Ross L., Kenigsberg, Ephraim, Abdel-Wahab, Omar, Landau, Dan A.
Publicado 2020

Epigenetic evolution and lineage histories of chronic lymphocytic leukemia

por Gaiti, Federico, Chaligne, Ronan, Gu, Hongcang, Brand, Ryan Matthew, Kothen-Hill, Steven, Schulman, Rafael, Grigorev, Kirill, Risso, Davide, Kim, Kyu-Tae, Pastore, Alessandro, Huang, Kevin Y., Alonso, Alicia, Sheridan, Caroline, Omans, Nathaniel D., Biederstedt, Evan, Clement, Kendell, Wang, Lili, Felsenfeld, Joshua A., Bhavsar, Erica B., Aryee, Martin J., Allan, John N., Furman, Richard, Gnirke, Andreas, Wu, Catherine J., Meissner, Alexander, Landau, Dan A.
Publicado 2019

Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription

por Edelmann, Jennifer, Holzmann, Karlheinz, Tausch, Eugen, Saunderson, Emily A., Jebaraj, Billy M. C., Steinbrecher, Daniela, Dolnik, Anna, Blätte, Tamara J., Landau, Dan A., Saub, Jenny, Estenfelder, Sven, Ibach, Stefan, Cymbalista, Florence, Leblond, Veronique, Delmer, Alain, Bahlo, Jasmin, Robrecht, Sandra, Fischer, Kirsten, Goede, Valentin, Bullinger, Lars, Wu, Catherine J., Mertens, Daniel, Ficz, Gabriella, Gribben, John G., Hallek, Michael, Döhner, Hartmut, Stilgenbauer, Stephan
Publicado 2020

Mutations driving CLL and their evolution in progression and relapse

por Landau, Dan A., Tausch, Eugen, Taylor-Weiner, Amaro N, Stewart, Chip, Reiter, Johannes G., Bahlo, Jasmin, Kluth, Sandra, Bozic, Ivana, Lawrence, Mike, Böttcher, Sebastian, Carter, Scott L., Cibulskis, Kristian, Mertens, Daniel, Sougnez, Carrie, Rosenberg, Mara, Hess, Julian M., Edelmann, Jennifer, Kless, Sabrina, Kneba, Michael, Ritgen, Matthias, Fink, Anna, Fischer, Kirsten, Gabriel, Stacey, Lander, Eric, Nowak, Martin A., Döhner, Hartmut, Hallek, Michael, Neuberg, Donna, Getz, Gad, Stilgenbauer, Stephan, Wu, Catherine J.
Publicado 2015

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia

por Bloehdorn, Johannes, Braun, Andrejs, Taylor-Weiner, Amaro, Jebaraj, Billy Michael Chelliah, Robrecht, Sandra, Krzykalla, Julia, Pan, Heng, Giza, Adam, Akylzhanova, Gulnara, Holzmann, Karlheinz, Scheffold, Annika, Johnston, Harvey E., Yeh, Ru-Fang, Klymenko, Tetyana, Tausch, Eugen, Eichhorst, Barbara, Bullinger, Lars, Fischer, Kirsten, Weisser, Martin, Robak, Tadeusz, Schneider, Christof, Gribben, John, Dahal, Lekh N., Carter, Mathew J., Elemento, Olivier, Landau, Dan A., Neuberg, Donna S., Cragg, Mark S., Benner, Axel, Hallek, Michael, Wu, Catherine J., Döhner, Hartmut, Stilgenbauer, Stephan, Mertens, Daniel
Publicado 2021

Resistance to checkpoint blockade therapy through inactivation of antigen presentation

por Sade-Feldman, Moshe, Jiao, Yunxin J., Chen, Jonathan H., Rooney, Michael S., Barzily-Rokni, Michal, Eliane, Jean-Pierre, Bjorgaard, Stacey L., Hammond, Marc R., Vitzthum, Hans, Blackmon, Shauna M., Frederick, Dennie T., Hazar-Rethinam, Mehlika, Nadres, Brandon A., Van Seventer, Emily E., Shukla, Sachet A., Yizhak, Keren, Ray, John P., Rosebrock, Daniel, Livitz, Dimitri, Adalsteinsson, Viktor, Getz, Gad, Duncan, Lyn M., Li, Bo, Corcoran, Ryan B., Lawrence, Donald P., Stemmer-Rachamimov, Anat, Boland, Genevieve M., Landau, Dan A., Flaherty, Keith T., Sullivan, Ryan J., Hacohen, Nir
Publicado 2017

Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition

por Burger, Jan A., Landau, Dan A., Taylor-Weiner, Amaro, Bozic, Ivana, Zhang, Huidan, Sarosiek, Kristopher, Wang, Lili, Stewart, Chip, Fan, Jean, Hoellenriegel, Julia, Sivina, Mariela, Dubuc, Adrian M., Fraser, Cameron, Han, Yulong, Li, Shuqiang, Livak, Kenneth J., Zou, Lihua, Wan, Youzhong, Konoplev, Sergej, Sougnez, Carrie, Brown, Jennifer R., Abruzzo, Lynne V., Carter, Scott L., Keating, Michael J., Davids, Matthew S., Wierda, William G., Cibulskis, Kristian, Zenz, Thorsten, Werner, Lillian, Cin, Paola Dal, Kharchencko, Peter, Neuberg, Donna, Kantarjian, Hagop, Lander, Eric, Gabriel, Stacey, O'Brien, Susan, Letai, Anthony, Weitz, David A., Nowak, Martin A., Getz, Gad, Wu, Catherine J.
Publicado 2016