Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity

por Quambusch, Lena, Landel, Ina, Depta, Laura, Weisner, Jörn, Uhlenbrock, Niklas, Müller, Matthias P., Glanemann, Franziska, Althoff, Kristina, Siveke, Jens T., Rauh, Daniel
Publicado 2019

Covalent Allosteric Inhibitors of Akt Generated Using a Click Fragment Approach

por van der Westhuizen, Leandi, Weisner, Jörn, Taher, Abu, Landel, Ina, Quambusch, Lena, Lindemann, Marius, Uhlenbrock, Niklas, Müller, Matthias P., Green, Ivan R., Pelly, Stephen C., Rauh, Daniel, van Otterlo, Willem A. L.
Publicado 2022

Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt

por Uhlenbrock, Niklas, Smith, Steven, Weisner, Jörn, Landel, Ina, Lindemann, Marius, Le, Thien Anh, Hardick, Julia, Gontla, Rajesh, Scheinpflug, Rebekka, Czodrowski, Paul, Janning, Petra, Depta, Laura, Quambusch, Lena, Müller, Matthias P., Engels, Bernd, Rauh, Daniel
Publicado 2019

Cellular model system to dissect the isoform-selectivity of Akt inhibitors

por Quambusch, Lena, Depta, Laura, Landel, Ina, Lubeck, Melissa, Kirschner, Tonia, Nabert, Jonas, Uhlenbrock, Niklas, Weisner, Jörn, Kostka, Michael, Levy, Laura M., Schultz-Fademrecht, Carsten, Glanemann, Franziska, Althoff, Kristina, Müller, Matthias P., Siveke, Jens T., Rauh, Daniel
Publicado 2021