Essays in English population history

por Landers, John
Publicado 1995

Armies of pestilence: the effects of pandemics on history

por Landers, John
Publicado 1998

Aldose Reductase Gene Polymorphisms and Diabetic Retinopathy Susceptibility

por Abhary, Sotoodeh, Burdon, Kathryn P., Laurie, Kate J., Thorpe, Stacey, Landers, John, Goold, Lucy, Lake, Stewart, Petrovsky, Nikolai, Craig, Jamie E.
Publicado 2010

Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis

por Giampetruzzi, Anthony, Danielson, Eric W., Gumina, Valentina, Jeon, Maryangel, Boopathy, Sivakumar, Brown, Robert H., Ratti, Antonia, Landers, John E., Fallini, Claudia
Publicado 2019

The Role of Copy Number Variation in Susceptibility to Amyotrophic Lateral Sclerosis: Genome-Wide Association Study and Comparison with Published Loci

por Wain, Louise V., Pedroso, Inti, Landers, John E., Breen, Gerome, Shaw, Christopher E., Leigh, P. Nigel, Brown, Robert H., Tobin, Martin D., Al-Chalabi, Ammar
Publicado 2009

Genetic Risk Assessment of Degenerative Eye Disease (GRADE): study protocol of a prospective assessment of polygenic risk scores to predict diagnosis of glaucoma and age-related ma...

por Hollitt, Georgina L, Qassim, Ayub, Thomson, Daniel, Schmidt, Joshua M, Nguyen, Thi Thi, Landers, John, MacGregor, Stuart, Siggs, Owen M, Souzeau, Emmanuelle, Craig, Jamie E
Publicado 2023

Characterization of FUS Mutations in Amyotrophic Lateral Sclerosis Using RNA-Seq

por van Blitterswijk, Marka, Wang, Eric T., Friedman, Brad A., Keagle, Pamela J., Lowe, Patrick, Leclerc, Ashley Lyn, van den Berg, Leonard H., Housman, David E., Veldink, Jan H., Landers, John E.
Publicado 2013

ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation

por Sama, Reddy Ranjith K., Fallini, Claudia, Gatto, Rodolfo, McKeon, Jeanne E., Song, Yuyu, Rotunno, Melissa S., Penaranda, Saul, Abdurakhmanov, Izrail, Landers, John E., Morfini, Gerardo, Brady, Scott T., Bosco, Daryl A.
Publicado 2017

Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls

por Simkin, Dina, Papakis, Vasileios, Bustos, Bernabe I., Ambrosi, Christina M., Ryan, Steven J., Baru, Valeriya, Williams, Luis A., Dempsey, Graham T., McManus, Owen B., Landers, John E., Lubbe, Steven J., George, Alfred L., Kiskinis, Evangelos
Publicado 2022

Prevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillance

por Awadalla, Mona S., Fitzgerald, Jude, Andrew, Nicholas H., Zhou, Tiger, Marshall, Henry, Qassim, Ayub, Hassall, Mark, Casson, Robert J., Graham, Stuart L., Healey, Paul R., Agar, Ashish, Galanopoulos, Anna, Phipps, Simon, Chappell, Angela, Landers, John, Craig, Jamie E.
Publicado 2018

Novel TUBA4A Variant Associated With Familial Frontotemporal Dementia

por Mol, Merel O., Wong, Tsz H., Melhem, Shamiram, Basu, Sreya, Viscusi, Riccardo, Galjart, Niels, Rozemuller, Annemieke J.M., Fallini, Claudia, Landers, John E., Kaat, Laura Donker, Seelaar, Harro, van Rooij, Jeroen G.J., van Swieten, John C.
Publicado 2021

Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import

por Mann, Jacob R., McKenna, Elizabeth D., Mawrie, Darilang, Papakis, Vasileios, Alessandrini, Francesco, Anderson, Eric N., Mayers, Ryan, Ball, Hannah E., Kaspi, Evan, Lubinski, Katherine, Baron, Desiree M., Tellez, Liana, Landers, John E., Pandey, Udai B., Kiskinis, Evangelos
Publicado 2023

Role of Lysosomal Gene Variants in Modulating GBA ‐Associated Parkinson's Disease Risk

por Straniero, Letizia, Rimoldi, Valeria, Monfrini, Edoardo, Bonvegna, Salvatore, Melistaccio, Giada, Lake, Julie, Soldà, Giulia, Aureli, Massimo, Shankaracharya, Keagle, Pamela, Foroud, Tatiana, Landers, John E., Blauwendraat, Cornelis, Zecchinelli, Anna, Cilia, Roberto, Di Fonzo, Alessio, Pezzoli, Gianni, Duga, Stefano, Asselta, Rosanna
Publicado 2022

Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types

por Saez-Atienzar, Sara, Bandres-Ciga, Sara, Langston, Rebekah G., Kim, Jonggeol J., Choi, Shing Wan, Reynolds, Regina H., Abramzon, Yevgeniya, Dewan, Ramita, Ahmed, Sarah, Landers, John E., Chia, Ruth, Ryten, Mina, Cookson, Mark R., Nalls, Michael A., Chiò, Adriano, Traynor, Bryan J.
Publicado 2021

A common haplotype within the PON1 promoter region is associated with sporadic ALS

por Landers, John E., Shi, Lijia, Cho, Ting-Jan, Glass, Jonathan D., Shaw, Christopher E., Leigh, P. Nigel, Diekstra, Frank, Polak, Meraida, Rodriguez-Leyva, Ildefonso, Niemann, Stephan, Traynor, Bryan J., Mckenna-Yasek, Diane, Sapp, Peter C., Al-Chalabi, Ammar, Wills, Anne-Marie A., Brown, Robert H.
Publicado 2008

Novel mutations support a role for Profilin 1 in the pathogenesis of ALS

por Smith, Bradley N., Vance, Caroline, Scotter, Emma L., Troakes, Claire, Wong, Chun Hao, Topp, Simon, Maekawa, Satomi, King, Andrew, Mitchell, Jacqueline C., Lund, Karan, Al-Chalabi, Ammar, Ticozzi, Nicola, Silani, Vincenzo, Sapp, Peter, Brown, Robert H., Landers, John E., Al-Sarraj, Safa, Shaw, Christopher E.
Publicado 2015

Rare variants in optic disc area gene CARD10 enriched in primary open‐angle glaucoma

por Zhou, Tiger, Souzeau, Emmanuelle, Sharma, Shiwani, Siggs, Owen M., Goldberg, Ivan, Healey, Paul R., Graham, Stuart, Hewitt, Alex W., Mackey, David A., Casson, Robert J., Landers, John, Mills, Richard, Ellis, Jonathan, Leo, Paul, Brown, Matthew A., MacGregor, Stuart, Burdon, Kathryn P., Craig, Jamie E.
Publicado 2016

The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1

por Perez Carrion, Maria, Pischedda, Francesca, Biosa, Alice, Russo, Isabella, Straniero, Letizia, Civiero, Laura, Guida, Marianna, Gloeckner, Christian J., Ticozzi, Nicola, Tiloca, Cinzia, Mariani, Claudio, Pezzoli, Gianni, Duga, Stefano, Pichler, Irene, Pan, Lifeng, Landers, John E., Greggio, Elisa, Hess, Michael W., Goldwurm, Stefano, Piccoli, Giovanni
Publicado 2018

Whole exome sequencing implicates eye development, the unfolded protein response and plasma membrane homeostasis in primary open-angle glaucoma

por Zhou, Tiger, Souzeau, Emmanuelle, Sharma, Shiwani, Landers, John, Mills, Richard, Goldberg, Ivan, Healey, Paul R., Graham, Stuart, Hewitt, Alex W., Mackey, David A., Galanopoulos, Anna, Casson, Robert J., Ruddle, Jonathan B., Ellis, Jonathan, Leo, Paul, Brown, Matthew A., MacGregor, Stuart, Lynn, David J., Burdon, Kathryn P., Craig, Jamie E.
Publicado 2017

Glaucoma spectrum and age-related prevalence of individuals with FOXC1 and PITX2 variants

por Souzeau, Emmanuelle, Siggs, Owen M, Zhou, Tiger, Galanopoulos, Anna, Hodson, Trevor, Taranath, Deepa, Mills, Richard A, Landers, John, Pater, John, Smith, James E, Elder, James E, Rait, Julian L, Giles, Paul, Phakey, Vivek, Staffieri, Sandra E, Kearns, Lisa S, Dubowsky, Andrew, Mackey, David A, Hewitt, Alex W, Ruddle, Jonathan B, Burdon, Kathryn P, Craig, Jamie E
Publicado 2017