Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models

por Landowski, Michael, Bowes Rickman, Catherine
Publicado 2022

Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice

por Landowski, Michael, Kelly, Una, Klingeborn, Mikael, Groelle, Marybeth, Ding, Jin-Dong, Grigsby, Daniel, Bowes Rickman, Catherine
Publicado 2019

A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups

por Landowski, Michael, Bhute, Vijesh J., Takimoto, Tetsuya, Grindel, Samuel, Shahi, Pawan K., Pattnaik, Bikash R., Ikeda, Sakae, Ikeda, Akihiro
Publicado 2022

Modulation of Tmem135 Leads to Retinal Pigmented Epithelium Pathologies in Mice

por Landowski, Michael, Grindel, Samuel, Shahi, Pawan K., Johnson, Abigail, Western, Daniel, Race, Adrienne, Shi, Franky, Benson, Jonathan, Gao, Marvin, Santoirre, Evelyn, Lee, Wei-Hua, Ikeda, Sakae, Pattnaik, Bikash R., Ikeda, Akihiro
Publicado 2020

Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration

por Toomey, Christopher B., Landowski, Michael, Klingeborn, Mikael, Kelly, Una, Deans, John, Dong, Holly, Harrabi, Ons, Van Blarcom, Thomas, Yeung, Yik Andy, Grishanin, Ruslan, Lin, John C., Saban, Daniel R., Bowes Rickman, Catherine
Publicado 2018

Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism

por Landowski, Michael, Bhute, Vijesh J., Grindel, Samuel, Haugstad, Zachary, Gyening, Yeboah K., Tytanic, Madison, Brush, Richard S., Moyer, Lucas J., Nelson, David W., Davis, Christopher R., Yen, Chi-Liang Eric, Ikeda, Sakae, Agbaga, Martin-Paul, Ikeda, Akihiro
Publicado 2023

Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in skt Mice

por Macke, Erica L., Henningsen, Erika, Jessen, Erik, Zumwalde, Nicholas A., Landowski, Michael, Western, Daniel E., Lee, Wei-Hua, Liu, Che, Gruenke, Nathan P., Doebley, Anna-Lisa, Miller, Samuel, Pattnaik, Bikash, Ikeda, Sakae, Gumperz, Jenny E., Ikeda, Akihiro
Publicado 2020