Complessita e modelli: un nuovo quadro interpretativo per la modellizzazione nelle scienze della nature e della societa

por Bertuglia, Cristoforo Sergio, Vaio, Franco, Lane, David A
Publicado 2011

A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von willebrand factor

por South, Kieron, Freitas, Marta O., Lane, David A.
Publicado 2017

A common mechanism by which type 2A von Willebrand disease mutations enhance ADAMTS13 proteolysis revealed with a von Willebrand factor A2 domain FRET construct

por Lynch, Christopher J., Cawte, Adam D., Millar, Carolyn M., Rueda, David, Lane, David A.
Publicado 2017

Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation

por Santamaria, Salvatore, Reglińska-Matveyev, Natalia, Gierula, Magdalena, Camire, Rodney M., Crawley, James T. B., Lane, David A., Ahnström, Josefin
Publicado 2017

Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis

por Santamaria, Salvatore, Yamamoto, Kazuhiro, Teraz-Orosz, Adrienn, Koch, Christopher, Apte, Suneel S., de Groot, Rens, Lane, David A., Ahnström, Josefin
Publicado 2019

The roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complex

por Gierula, Magdalena, Salles‐Crawley, Isabelle I., Santamaria, Salvatore, Teraz‐Orosz, Adrienn, Crawley, James T. B., Lane, David A., Ahnström, Josefin
Publicado 2019

Protective Effects of Non-Anticoagulant Activated Protein C Variant (D36A/L38D/A39V) in a Murine Model of Ischaemic Stroke

por Andreou, Anna P., Efthymiou, Maria, Yu, Yao, Watts, Helena R., Noormohamed, Faruq H., Ma, Daqing, Lane, David A., Crawley, James TB
Publicado 2015

Defective fibrin deposition and thrombus stability in Bambi (−/−) mice are mediated by elevated anticoagulant function

por Crawley, James T. B., Zalli, Argita, Monkman, James H., Petri, Anastasis, Lane, David A., Ahnstrӧm, Josefin, Salles‐Crawley, Isabelle I.
Publicado 2019

Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain

por Andersson, Helena M., Arantes, Márcia J., Crawley, James T. B., Luken, Brenda M., Tran, Sinh, Dahlbäck, Björn, Lane, David A., Rezende, Suely M.
Publicado 2010

Laminin G1 residues of protein S mediate its TFPI cofactor function and are competitively regulated by C4BP

por Teraz-Orosz, Adrienn, Gierula, Magdalena, Petri, Anastasis, Jones, David, Keniyopoullos, Renos, Folgado, Patricia Badia, Santamaria, Salvatore, Crawley, James T. B., Lane, David A., Ahnström, Josefin
Publicado 2022

Biphasic activation of complement and fibrinolysis during the human nasal allergic response

por Thwaites, Ryan S., Gunawardana, Natasha C., Broich, Verena, Mann, Elizabeth H., Ahnström, Josefin, Campbell, Gaynor A., Lindsley, Sarah, Singh, Nehmat, Tunstall, Tanushree, Lane, David A., Openshaw, Peter J., Hawrylowicz, Catherine M., Hansel, Trevor T.
Publicado 2018

The ADAMTS13–VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension

por Newnham, Michael, South, Kieron, Bleda, Marta, Auger, William R., Barberà, Joan A., Bogaard, Harm, Bunclark, Katherine, Cannon, John E., Delcroix, Marion, Hadinnapola, Charaka, Howard, Luke S., Jenkins, David, Mayer, Eckhard, Ng, Choo, Rhodes, Christopher J., Screaton, Nicholas, Sheares, Karen, Simpson, Michael A., Southwood, Mark, Su, Li, Taboada, Dolores, Traylor, Matthew, Trembath, Richard C., Villar, Sofia S., Wilkins, Martin R., Wharton, John, Gräf, Stefan, Pepke-Zaba, Joanna, Laffan, Michael, Lane, David A., Morrell, Nicholas W., Toshner, Mark
Publicado 2019