Investigation of MicroRNA-134 as a Target against Seizures and SUDEP in a Mouse Model of Dravet Syndrome

por Gerbatin, Rogério R., Augusto, Joana, Morris, Gareth, Campbell, Aoife, Worm, Jesper, Langa, Elena, Reschke, Cristina R., Henshall, David C.
Publicado 2022

Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice

por Ichikawa, Naoki, Alves, Mariana, Pfeiffer, Shona, Langa, Elena, Hernández-Santana, Yasmina E, Suzuki, Hidenori, Prehn, Jochen HM, Engel, Tobias, Henshall, David C
Publicado 2017

Antagomir-mediated suppression of microRNA-134 reduces kainic acid-induced seizures in immature mice

por Campbell, Aoife, Morris, Gareth, Heller, Janosch P., Langa, Elena, Brindley, Elizabeth, Worm, Jesper, Jensen, Mads Aaboe, Miller, Meghan T., Henshall, David C., Reschke, Cristina R.
Publicado 2021

Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus

por Batool, Aasia, Hill, Thomas D. M., Nguyen, Ngoc T., Langa, Elena, Diviney, Mairéad, Mooney, Catherine, Brennan, Gary P., Connolly, Niamh M. C., Sanz-Rodriguez, Amaya, Cavanagh, Brenton L., Henshall, David C.
Publicado 2020

Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice

por Almeida Silva, Luiz F., Reschke, Cristina R., Nguyen, Ngoc T., Langa, Elena, Sanz-Rodriguez, Amaya, Gerbatin, Rogerio R., Temp, Fernanda R., de Freitas, Mayara L., Conroy, Ronan M., Brennan, Gary P., Engel, Tobias, Henshall, David C.
Publicado 2020

AntimiR targeting of microRNA-134 reduces seizures in a mouse model of Angelman syndrome

por Campbell, Aoife, Morris, Gareth, Sanfeliu, Albert, Augusto, Joana, Langa, Elena, Kesavan, Jaideep C., Nguyen, Ngoc T., Conroy, Ronan M., Worm, Jesper, Kielpinski, Lukasz, Jensen, Mads Aaboe, Miller, Meghan T., Kremer, Thomas, Reschke, Cristina R., Henshall, David C.
Publicado 2022

MicroRNA inhibition using antimiRs in acute human brain tissue sections

por Morris, Gareth, Langa, Elena, Fearon, Conor, Conboy, Karen, Lau E‐How, Kelvin, Sanz‐Rodriguez, Amaya, O'Brien, Donncha F., Sweeney, Kieron, Lacey, Austin, Delanty, Norman, Beausang, Alan, Brett, Francesca M., Cryan, Jane B., Cunningham, Mark O., Henshall, David C.
Publicado 2022

Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy

por Brindley, Elizabeth, Heiland, Mona, Mooney, Catherine, Diviney, Mairead, Mamad, Omar, Hill, Thomas D. M., Yan, Yan, Venø, Morten T., Reschke, Cristina R., Batool, Aasia, Langa, Elena, Sanz-Rodriguez, Amaya, Heller, Janosch P., Morris, Gareth, Conboy, Karen, Kjems, Jørgen, Brennan, Gary P., Henshall, David C.
Publicado 2023

MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control

por Heiland, Mona, Connolly, Niamh M. C., Mamad, Omar, Nguyen, Ngoc T., Kesavan, Jaideep C., Langa, Elena, Fanning, Kevin, Sanfeliu, Albert, Yan, Yan, Su, Junyi, Venø, Morten T., Costard, Lara S., Neubert, Valentin, Engel, Tobias, Hill, Thomas D. M., Freiman, Thomas M., Mahesh, Arun, Tiwari, Vijay K., Rosenow, Felix, Bauer, Sebastian, Kjems, Jørgen, Morris, Gareth, Henshall, David C.
Publicado 2023

microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus

por Jimenez-Mateos, Eva M., Arribas-Blazquez, Marina, Sanz-Rodriguez, Amaya, Concannon, Caoimhin, Olivos-Ore, Luis A., Reschke, Cristina R., Mooney, Claire M., Mooney, Catherine, Lugara, Eleonora, Morgan, James, Langa, Elena, Jimenez-Pacheco, Alba, Silva, Luiz Fernando Almeida, Mesuret, Guillaume, Boison, Detlev, Miras-Portugal, M. Teresa, Letavic, Michael, Artalejo, Antonio R., Bhattacharya, Anindya, Diaz-Hernandez, Miguel, Henshall, David C., Engel, Tobias
Publicado 2015

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

por Venø, Morten T., Reschke, Cristina R., Morris, Gareth, Connolly, Niamh M. C., Su, Junyi, Yan, Yan, Engel, Tobias, Jimenez-Mateos, Eva M., Harder, Lea M., Pultz, Dennis, Haunsberger, Stefan J., Pal, Ajay, Heller, Janosch P., Campbell, Aoife, Langa, Elena, Brennan, Gary P., Conboy, Karen, Richardson, Amy, Norwood, Braxton A., Costard, Lara S., Neubert, Valentin, Del Gallo, Federico, Salvetti, Beatrice, Vangoor, Vamshidhar R., Sanz-Rodriguez, Amaya, Muilu, Juha, Fabene, Paolo F., Pasterkamp, R. Jeroen, Prehn, Jochen H. M., Schorge, Stephanie, Andersen, Jens S., Rosenow, Felix, Bauer, Sebastian, Kjems, Jørgen, Henshall, David C.
Publicado 2020