Estrogen Receptor Signaling in Cancer

por Langdon, Simon P.
Publicado 2020

Inhibitors of the Fanconi anaemia pathway as potential antitumour agents for ovarian cancer

por Taylor, Sarah J, Arends, Mark J, Langdon, Simon P
Publicado 2020

Estrogen Signaling and Its Potential as a Target for Therapy in Ovarian Cancer

por Langdon, Simon P., Herrington, C. Simon, Hollis, Robert L., Gourley, Charlie
Publicado 2020

Emerging role of nuclear factor erythroid 2-related factor 2 in the mechanism of action and resistance to anticancer therapies

por Paramasivan, Poornima, Kankia, Ibrahim H., Langdon, Simon P., Deeni, Yusuf Y.
Publicado 2019

A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen

por Lebedeva, Galina, Yamaguchi, Azusa, Langdon, Simon P, Macleod, Kenneth, Harrison, David J
Publicado 2012

Customizing the Therapeutic Response of Signaling Networks to Promote Antitumor Responses by Drug Combinations

por Goltsov, Alexey, Langdon, Simon P., Goltsov, Gregory, Harrison, David J., Bown, James
Publicado 2014

Evaluation of Gene Expression Data From Cybrids and Tumours Highlights Elevated NDRG1-Driven Proliferation in Triple-Negative Breast Cancer

por Mishra, Akanksha, Bonello, Maria, Byron, Adam, Langdon, Simon P, Sims, Andrew H
Publicado 2020

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

por Koussounadis, Antonis, Langdon, Simon P., Um, In Hwa, Harrison, David J., Smith, V. Anne
Publicado 2015

Novel Monte Carlo approach quantifies data assemblage utility and reveals power of integrating molecular and clinical information for cancer prognosis

por Verleyen, Wim, Langdon, Simon P., Faratian, Dana, Harrison, David J., Smith, V. Anne
Publicado 2015

NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies

por Khalil, Hilal S., Langdon, Simon P., Kankia, Ibrahim H., Bown, James, Deeni, Yusuf Y.
Publicado 2016

A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models

por Xintaropoulou, Chrysi, Ward, Carol, Wise, Alan, Marston, Hugh, Turnbull, Arran, Langdon, Simon P.
Publicado 2015

Nuclear factor erythroid 2-related factor 2 modulates HER4 receptor in ovarian cancer cells to influence their sensitivity to tyrosine kinase inhibitors

por Kankia, Ibrahim H., Paramasivan, Poornima, Elcombe, Matthew, Langdon, Simon P., Deeni, Yusuf Y.
Publicado 2021

Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness

por Ward, Carol, Meehan, James, Gray, Mark, Kunkler, Ian H., Langdon, Simon P., Argyle, David J.
Publicado 2018

The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer

por Huang, Rui, Langdon, Simon P, Tse, Matthew, Mullen, Peter, Um, In Hwa, Faratian, Dana, Harrison, David J
Publicado 2015

Increased STAT1 Signaling in Endocrine-Resistant Breast Cancer

por Huang, Rui, Faratian, Dana, Sims, Andrew H., Wilson, Danielle, Thomas, Jeremy S., Harrison, David J., Langdon, Simon P.
Publicado 2014

Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers

por Briffa, Romina, Um, Inhwa, Faratian, Dana, Zhou, Ying, Turnbull, Arran K., Langdon, Simon P., Harrison, David J.
Publicado 2015

A novel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2 function in ovarian cancer cells

por Khalil, Hilal S., Langdon, Simon P., Goltsov, Alexey, Soininen, Tero, Harrison, David J., Bown, James, Deeni, Yusuf Y.
Publicado 2016

NRF2 Regulates HER1 Signaling Pathway to Modulate the Sensitivity of Ovarian Cancer Cells to Lapatinib and Erlotinib

por Kankia, Ibrahim H., Khalil, Hilal S., Langdon, Simon P., Moult, Peter R., Bown, James L., Deeni, Yusuf Y.
Publicado 2017

Sprouty 2 Is an Independent Prognostic Factor in Breast Cancer and May Be Useful in Stratifying Patients for Trastuzumab Therapy

por Faratian, Dana, Sims, Andrew H., Mullen, Peter, Kay, Charlene, Um, InHwa, Langdon, Simon P., Harrison, David J.
Publicado 2011

Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network

por Lebedeva, Galina, Sorokin, Anatoly, Faratian, Dana, Mullen, Peter, Goltsov, Alexey, Langdon, Simon P., Harrison, David J., Goryanin, Igor
Publicado 2012