Diphtheria Toxin A-Resistant Cell Lines Enable Robust Production and Evaluation of DTA-Encoding Lentiviruses

por Lange, Margaret J., Lyddon, Terri D., Johnson, Marc C.
Publicado 2019

RNA–protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers

por Lange, Margaret J., Nguyen, Phuong D. M., Callaway, Mackenzie K., Johnson, Marc C., Burke, Donald H.
Publicado 2017

Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers

por Alam, Khalid K., Chang, Jonathan L., Lange, Margaret J., Nguyen, Phuong D.M., Sawyer, Andrew W., Burke, Donald H.
Publicado 2018

Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication

por Gruenke, Paige R, Aneja, Rachna, Welbourn, Sarah, Ukah, Obiaara B, Sarafianos, Stefan G, Burke, Donald H, Lange, Margaret J
Publicado 2022

Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines

por Porciani, David, Cardwell, Leah N., Tawiah, Kwaku D., Alam, Khalid K., Lange, Margaret J., Daniels, Mark A., Burke, Donald H.
Publicado 2018

GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds

por Singh, Kamal, Gallazzi, Fabio, Hill, Kyle J., Burke, Donald H., Lange, Margaret J., Quinn, Thomas P., Neogi, Ujjwal, Sönnerborg, Anders
Publicado 2019

Potent Inhibition of HIV-1 Reverse Transcriptase and Replication by Nonpseudoknot, “UCAA-motif” RNA Aptamers

por Whatley, Angela S, Ditzler, Mark A, Lange, Margaret J, Biondi, Elisa, Sawyer, Andrew W, Chang, Jonathan L, Franken, Joshua D, Burke, Donald H
Publicado 2013

High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase

por Ditzler, Mark A., Lange, Margaret J., Bose, Debojit, Bottoms, Christopher A., Virkler, Katherine F., Sawyer, Andrew W., Whatley, Angela S., Spollen, William, Givan, Scott A., Burke, Donald H.
Publicado 2013

The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity

por Song, Zhenwei, Gremminger, Thomas, Singh, Gatikrushna, Cheng, Yi, Li, Jun, Qiu, Liming, Ji, Juan, Lange, Margaret J, Zuo, Xiaobing, Chen, Shi-Jie, Zou, Xiaoqin, Boris-Lawrie, Kathleen, Heng, Xiao
Publicado 2021

Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase

por Nguyen, Phuong D M, Zheng, Jie, Gremminger, Thomas J, Qiu, Liming, Zhang, Dong, Tuske, Steve, Lange, Margaret J, Griffin, Patrick R, Arnold, Eddy, Chen, Shi-Jie, Zou, Xiaoqin, Heng, Xiao, Burke, Donald H
Publicado 2020

Lower female survival from an opportunistic infection reveals progesterone-driven sex bias in trained immunity

por Earhart, Alexander P., Karasseva, Natalia G., Storey, Kathryn M., Olthoff, Benjamin, Sarker, Md Bodruzzaman, Laffey, Kimberly G., Lange, Margaret J., Rector, R. Scott, Schulz, Laura C., Gil, Diana, Neuhauser, Claudia M., Schrum, Adam G.
Publicado 2023