TopFIND 2.0—linking protein termini with proteolytic processing and modifications altering protein function

por Lange, Philipp F., Huesgen, Pitter F., Overall, Christopher M.
Publicado 2012

Annotating N Termini for the Human Proteome Project: N Termini and Nα-Acetylation Status Differentiate Stable Cleaved Protein Species from Degradation Remnants in the Human Erythro...

por Lange, Philipp F., Huesgen, Pitter F., Nguyen, Karen, Overall, Christopher M.
Publicado 2014

Robust unsupervised deconvolution of linear motifs characterizes 68 protein modifications at proteome scale

por Smith, Theodore G., Uzozie, Anuli C., Chen, Siyuan, Lange, Philipp F.
Publicado 2021

Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events

por Fortelny, Nikolaus, Yang, Sharon, Pavlidis, Paul, Lange, Philipp F., Overall, Christopher M.
Publicado 2014

Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web

por Fortelny, Nikolaus, Cox, Jennifer H., Kappelhoff, Reinhild, Starr, Amanda E., Lange, Philipp F., Pavlidis, Paul, Overall, Christopher M.
Publicado 2014

Multi-omic profiling of the leukemic microenvironment shows bone marrow interstitial fluid is distinct from peripheral blood plasma

por Nierves, Lorenz, Guo, Jian, Chen, Siyuan, Tsui, Janice, Uzozie, Anuli C., Bush, Jonathan W., Huan, Tao, Lange, Philipp F.
Publicado 2022

Proteomic Amino-Termini Profiling Reveals Targeting Information for Protein Import into Complex Plastids

por Huesgen, Pitter F., Alami, Meriem, Lange, Philipp F., Foster, Leonard J., Schröder, Wolfgang P., Overall, Christopher M., Green, Beverley R.
Publicado 2013

Adaptation of the Th-MYCN Mouse Model of Neuroblastoma for Evaluation of Disseminated Disease

por Rahavi, Seyed M., Aletaha, Maryam, Farrokhi, Ali, Lorentzian, Amanda, Lange, Philipp F., Maxwell, Christopher A., Lim, Chinten James, Reid, Gregor S. D.
Publicado 2023

A cross‐standardized flow cytometry platform to assess phenotypic stability in precursor B‐cell acute lymphoblastic leukemia (B‐ALL) xenografts

por Rolf, Nina, Liu, Lorraine Y. T., Tsang, Angela, Lange, Philipp F., Lim, Chinten James, Maxwell, Christopher A., Vercauteren, Suzanne M., Reid, Gregor S. D.
Publicado 2021

Sensitive Determination of Proteolytic Proteoforms in Limited Microscale Proteome Samples

por Weng, Samuel S. H., Demir, Fatih, Ergin, Enes K., Dirnberger, Sabrina, Uzozie, Anuli, Tuscher, Domenic, Nierves, Lorenz, Tsui, Janice, Huesgen, Pitter F., Lange, Philipp F.
Publicado 2019

RNA Polymerase II transcription independent of TBP in murine embryonic stem cells

por Kwan, James ZJ, Nguyen, Thomas F, Uzozie, Anuli C, Budzynski, Marek A, Cui, Jieying, Lee, Joseph MC, Van Petegem, Filip, Lange, Philipp F, Teves, Sheila S
Publicado 2023

Targetable lesions and proteomes predict therapy sensitivity through disease evolution in pediatric acute lymphoblastic leukemia

por Lorentzian, Amanda C., Rever, Jenna, Ergin, Enes K., Guo, Meiyun, Akella, Neha M., Rolf, Nina, James Lim, C., Reid, Gregor S. D., Maxwell, Christopher A., Lange, Philipp F.
Publicado 2023

Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation

por He, Zhengcheng, Ghorayeb, Ryan, Tan, Susanna, Chen, Ke, Lorentzian, Amanda C., Bottyan, Jack, Aalam, Syed Mohammed Musheer, Pujana, Miguel Angel, Lange, Philipp F., Kannan, Nagarajan, Eaves, Connie J., Maxwell, Christopher A.
Publicado 2022

PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways

por Uzozie, Anuli C., Ergin, Enes K., Rolf, Nina, Tsui, Janice, Lorentzian, Amanda, Weng, Samuel S. H., Nierves, Lorenz, Smith, Theodore G., Lim, C. James, Maxwell, Christopher A., Reid, Gregor S. D., Lange, Philipp F.
Publicado 2021

Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies

por Lorentzian, Amanda, Biegel, Jaclyn A, Ostrow, D Gigi, Rolf, Nina, Liu, Chi-Chao, Rassekh, S Rod, Deyell, Rebecca J, Triche, Timothy, Schultz, Kirk R, Rozmus, Jacob, Reid, Gregor S D, Lim, C James, Lange, Philipp F, Maxwell, Christopher A
Publicado 2019

Multi-Omic Approach to Identify Phenotypic Modifiers Underlying Cerebral Demyelination in X-Linked Adrenoleukodystrophy

por Richmond, Phillip A., van der Kloet, Frans, Vaz, Frederic M., Lin, David, Uzozie, Anuli, Graham, Emma, Kobor, Michael, Mostafavi, Sara, Moerland, Perry D., Lange, Philipp F., van Kampen, Antoine H. C., Wasserman, Wyeth W., Engelen, Marc, Kemp, Stephan, van Karnebeek, Clara D. M.
Publicado 2020

Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14

por Eckhard, Ulrich, Huesgen, Pitter F., Schilling, Oliver, Bellac, Caroline L., Butler, Georgina S., Cox, Jennifer H., Dufour, Antoine, Goebeler, Verena, Kappelhoff, Reinhild, auf dem Keller, Ulrich, Klein, Theo, Lange, Philipp F., Marino, Giada, Morrison, Charlotte J., Prudova, Anna, Rodriguez, David, Starr, Amanda E., Wang, Yili, Overall, Christopher M.
Publicado 2016

HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development

por Connell, Marisa, Chen, Helen, Jiang, Jihong, Kuan, Chia-Wei, Fotovati, Abbas, Chu, Tony LH, He, Zhengcheng, Lengyell, Tess C, Li, Huaibiao, Kroll, Torsten, Li, Amanda M, Goldowitz, Daniel, Frappart, Lucien, Ploubidou, Aspasia, Patel, Millan S, Pilarski, Linda M, Simpson, Elizabeth M, Lange, Philipp F, Allan, Douglas W, Maxwell, Christopher A
Publicado 2017

Modification of BRCA1-associated breast cancer risk by HMMR overexpression

por Mateo, Francesca, He, Zhengcheng, Mei, Lin, de Garibay, Gorka Ruiz, Herranz, Carmen, García, Nadia, Lorentzian, Amanda, Baiges, Alexandra, Blommaert, Eline, Gómez, Antonio, Mirallas, Oriol, Garrido-Utrilla, Anna, Palomero, Luis, Espín, Roderic, Extremera, Ana I., Soler-Monsó, M. Teresa, Petit, Anna, Li, Rong, Brunet, Joan, Chen, Ke, Tan, Susanna, Eaves, Connie J., McCloskey, Curtis, Hakem, Razq, Khokha, Rama, Lange, Philipp F., Lázaro, Conxi, Maxwell, Christopher A., Pujana, Miquel Angel
Publicado 2022