PIN1 Provides Dynamic Control of MYC in Response to Extrinsic Signals

por Cohn, Gabriel M., Liefwalker, Daniel F., Langer, Ellen M., Sears, Rosalie C.
Publicado 2020

Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer

por Chapman, Margaret P., Risom, Tyler, Aswani, Anil J., Langer, Ellen M., Sears, Rosalie C., Tomlin, Claire J.
Publicado 2019

Correction: Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer

por Chapman, Margaret P., Risom, Tyler, Aswani, Anil J., Langer, Ellen M., Sears, Rosalie C., Tomlin, Claire J.
Publicado 2019

Altering MYC phosphorylation in the epidermis increases the stem cell population and contributes to the development, progression, and metastasis of squamous cell carcinoma

por Wang, Xiaoyan, Langer, Ellen M., Daniel, Colin J., Janghorban, Mahnaz, Wu, Vivian, Wang, Xiao-Jing, Sears, Rosalie C.
Publicado 2020

Snail and the microRNA-200 Family Act in Opposition to Regulate Epithelial-to-Mesenchymal Transition and Germ Layer Fate Restriction in Differentiating ESCs

por Gill, Jennifer G, Langer, Ellen M, Lindsley, R Coleman, Cai, Mi, Murphy, Theresa L, Kyba, Michael, Murphy, Kenneth M
Publicado 2011

The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model

por Janghorban, Mahnaz, Langer, Ellen M., Wang, Xiaoyan, Zachman, Derek, Daniel, Colin J., Hooper, Jody, Fleming, William H., Agarwal, Anupriya, Sears, Rosalie C.
Publicado 2017

The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis

por Jones, Kevin B., Barrott, Jared J., Xie, Mingchao, Haldar, Malay, Jin, Huifeng, Zhu, Ju-Fen, Monument, Michael J., Mosbruger, Tim L., Langer, Ellen M., Randall, R. Lor, Wilson, Richard K., Cairns, Bradley R., Ding, Li, Capecchi, Mario R.
Publicado 2016

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

por Risom, Tyler, Langer, Ellen M., Chapman, Margaret P., Rantala, Juha, Fields, Andrew J., Boniface, Christopher, Alvarez, Mariano J., Kendsersky, Nicholas D., Pelz, Carl R., Johnson-Camacho, Katherine, Dobrolecki, Lacey E., Chin, Koei, Aswani, Anil J., Wang, Nicholas J., Califano, Andrea, Lewis, Michael T., Tomlin, Claire J., Spellman, Paul T., Adey, Andrew, Gray, Joe W., Sears, Rosalie C.
Publicado 2018

Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting

por Langer, Ellen M., Allen-Petersen, Brittany L., King, Shelby M., Kendsersky, Nicholas D., Turnidge, Megan A., Kuziel, Genevra M., Riggers, Rachelle, Samatham, Ravi, Amery, Taylor S., Jacques, Steven L., Sheppard, Brett C., Korkola, James E., Muschler, John L., Thibault, Guillaume, Chang, Young Hwan, Gray, Joe W., Presnell, Sharon C., Nguyen, Deborah G., Sears, Rosalie C.
Publicado 2019

MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer

por Doha, Zinab O., Wang, Xiaoyan, Calistri, Nicholas L., Eng, Jennifer, Daniel, Colin J., Ternes, Luke, Kim, Eun Na, Pelz, Carl, Munks, Michael, Betts, Courtney, Kwon, Sunjong, Bucher, Elmar, Li, Xi, Waugh, Trent, Tatarova, Zuzana, Blumberg, Dylan, Ko, Aaron, Kirchberger, Nell, Pietenpol, Jennifer A., Sanders, Melinda E., Langer, Ellen M., Dai, Mu-Shui, Mills, Gordon, Chin, Koei, Chang, Young Hwan, Coussens, Lisa M., Gray, Joe W., Heiser, Laura M., Sears, Rosalie C.
Publicado 2023