Use of imaging to assess the activity of hepatic transporters

por Hernández Lozano, Irene, Langer, Oliver
Publicado 2020

Imaging P‐Glycoprotein Function at the Blood–Brain Barrier as a Determinant of the Variability in Response to Central Nervous System Drugs

por Bauer, Martin, Tournier, Nicolas, Langer, Oliver
Publicado 2019

Pharmacokinetic Imaging with Radiolabeled Molecularly Targeted Anticancer Drugs

por Bauer, Martin, Zeitlinger, Markus, Langer, Oliver
Publicado 2020

Liver Imaging and Hepatobiliary Contrast Media

por Pastor, Catherine M., Langer, Oliver, Van Beers, Bernard E.
Publicado 2018

PET imaging of the mouse brain reveals a dynamic regulation of SERT density in a chronic stress model

por Reisinger, Sonali N., Wanek, Thomas, Langer, Oliver, Pollak, Daniela D.
Publicado 2019

[(11)C]Elacridar as a novel P-glycoprotein PET tracer, assessment of whole-body distribution and radiation dosimetry in humans

por Bauer, Martin, Zeitlinger, Markus, Dobrozemsky, Georg, Philippe, Cécile, Müller, Markus, Langer, Oliver
Publicado 2011

Strategic, feasibility, economic, and cultural aspects of phase 0 approaches: Is it time to change the drug development process in order to increase productivity?

por Burt, Tal, Roffel, Ad F., Langer, Oliver, Anderson, Kirsten, DiMasi, Joseph
Publicado 2022

Pitfalls and solutions of the fully-automated radiosynthesis of [(11)C]metoclopramide

por Pichler, Verena, Ozenil, Marius, Bamminger, Karsten, Vraka, Chrysoula, Hacker, Marcus, Langer, Oliver, Wadsak, Wolfgang
Publicado 2019

Decreased blood-brain barrier P-glycoprotein function with aging

por Bauer, Martin, Karch, Rudolf, Abrahim, Aiman, Wagner, Claudia C, Kletter, Kurt, Müller, Markus, Langer, Oliver
Publicado 2008

Dose-response assessment of tariquidar for inhibition of P-glycoprotein at the human blood-brain barrier using (R)-[(11)C]verapamil PET

por Bauer, Martin, Zeitlinger, Markus, Matzneller, Peter, Stanek, Johann, Lackner, Edith, Wadsak, Wolfgang, Müller, Markus, Langer, Oliver
Publicado 2010

Impact of rifampicin-inhibitable transport on the liver distribution and tissue kinetics of erlotinib assessed with PET imaging in rats

por Amor, Dorra, Goutal, Sébastien, Marie, Solène, Caillé, Fabien, Bauer, Martin, Langer, Oliver, Auvity, Sylvain, Tournier, Nicolas
Publicado 2018

Humanization of the Blood–Brain Barrier Transporter ABCB1 in Mice Disrupts Genomic Locus — Lessons from Three Unsuccessful Approaches

por Krohn, Markus, Wanek, Thomas, Menet, Marie-Claude, Noack, Andreas, Declèves, Xavier, Langer, Oliver, Löscher, Wolfgang, Pahnke, Jens
Publicado 2018

Imaging-Based Characterization of a Slco2b1((-/-)) Mouse Model Using [(11)C]Erlotinib and [(99m)Tc]Mebrofenin as Probe Substrates

por Marie, Solène, Hernández-Lozano, Irene, Breuil, Louise, Truillet, Charles, Hu, Shuiying, Sparreboom, Alex, Tournier, Nicolas, Langer, Oliver
Publicado 2021

A PET microdosing study with the P-glycoprotein inhibitor tariquidar

por Bauer, Martin, Zeitlinger, Markus, Philippe, Cécile, Stanek, Johann, Wadsak, Wolfgang, Mitterhauser, Markus, Karanikas, Georgios, Müller, Markus, Langer, Oliver
Publicado 2012

Pharmacokinetic modeling of P-glycoprotein function at the rat and human blood–brain barriers studied with (R)-[(11)C]verapamil positron emission tomography

por Müllauer, Julia, Kuntner, Claudia, Bauer, Martin, Bankstahl, Jens P, Müller, Markus, Voskuyl, Rob A, Langer, Oliver, Syvänen, Stina
Publicado 2012

Factors That Limit Positron Emission Tomography Imaging of P-Glycoprotein Density at the Blood–Brain Barrier

por Kannan, Pavitra, Pike, Victor W., Halldin, Christer, Langer, Oliver, Gottesman, Michael M., Innis, Robert B., Hall, Matthew D.
Publicado 2013

Inhibition of breast cancer resistance protein at the murine blood-brain barrier by Ko143 studied with [(11)C]tariquidar and PET

por Wanek, Thomas, Kuntner, Claudia, Bankstahl, Jens P, Bankstahl, Marion, Stanek, Johann, Sauberer, Michael, Müller, Markus, Löscher, Wolfgang, Langer, Oliver
Publicado 2011

(R)-[(11)C]verapamil is selectively transported by murine and human P-glycoprotein at the blood–brain barrier, and not by MRP1 and BCRP

por Römermann, Kerstin, Wanek, Thomas, Bankstahl, Marion, Bankstahl, Jens P., Fedrowitz, Maren, Müller, Markus, Löscher, Wolfgang, Kuntner, Claudia, Langer, Oliver
Publicado 2013

Pharmacokinetics of the P-gp Inhibitor Tariquidar in Rats After Intravenous, Oral, and Intraperitoneal Administration

por Matzneller, Peter, Kussmann, Manuel, Eberl, Sabine, Maier-Salamon, Alexandra, Jäger, Walter, Bauer, Martin, Langer, Oliver, Zeitlinger, Markus, Poeppl, Wolfgang
Publicado 2018

Towards Improved Pharmacokinetic Models for the Analysis of Transporter-Mediated Hepatic Disposition of Drug Molecules with Positron Emission Tomography

por Hernández Lozano, Irene, Karch, Rudolf, Bauer, Martin, Blaickner, Matthias, Matsuda, Akihiro, Wulkersdorfer, Beatrix, Hacker, Marcus, Zeitlinger, Markus, Langer, Oliver
Publicado 2019