Crystal structure of duck egg lysozyme isoform II (DEL-II)

por Langley, David B., Christ, Daniel
Publicado 2018

PROTAC targeted protein degraders: the past is prologue

por Békés, Miklós, Langley, David R., Crews, Craig M.
Publicado 2022

Social media use in healthcare: A systematic review of effects on patients and on their relationship with healthcare professionals

por Smailhodzic, Edin, Hooijsma, Wyanda, Boonstra, Albert, Langley, David J.
Publicado 2016

A highly accurate metadynamics-based Dissociation Free Energy method to calculate protein–protein and protein–ligand binding potencies

por Wang, Jing, Ishchenko, Alexey, Zhang, Wei, Razavi, Asghar, Langley, David
Publicado 2022

Next-Generation Sequencing of Antibody Display Repertoires

por Rouet, Romain, Jackson, Katherine J. L., Langley, David B., Christ, Daniel
Publicado 2018

Mechanistic Characterization and Molecular Modeling of Hepatitis B Virus Polymerase Resistance to Entecavir

por Walsh, Ann W., Langley, David R., Colonno, Richard J., Tenney, Daniel J.
Publicado 2010

Mutagenic Activation of Glutathione Peroxidase-4: Approaches toward Rational Design of Allosteric Drugs

por Ma, Chunyue, Chung, Daniel J., Abramson, Dylan, Langley, David R., Thayer, Kelly M.
Publicado 2022

Surface-associated antigen induces permeabilization of primary mouse B-cells and lysosome exocytosis facilitating antigen uptake and presentation to T-cells

por Maeda, Fernando Y, van Haaren, Jurriaan JH, Langley, David B, Christ, Daniel, Andrews, Norma W, Song, Wenxia
Publicado 2021

The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors

por Lambert, Sebastian M, Langley, David R, Garnett, James A, Angell, Richard, Hedgethorne, Katy, Meanwell, Nicholas A, Matthews, Steve J
Publicado 2014

Structural basis of antigen recognition: crystal structure of duck egg lysozyme

por Langley, David Brent, Crossett, Ben, Schofield, Peter, Jackson, Jenny, Zeraati, Mahdi, Maltby, David, Christie, Mary, Burnett, Deborah, Brink, Robert, Goodnow, Christopher, Christ, Daniel
Publicado 2017

Homology models of the HIV-1 attachment inhibitor BMS-626529 bound to gp120 suggest a unique mechanism of action

por Langley, David R, Roy Kimura, S, Sivaprakasam, Prasanna, Zhou, Nannan, Dicker, Ira, McAuliffe, Brian, Wang, Tao, Kadow, John F, Meanwell, Nicholas A, Krystal, Mark
Publicado 2015

Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens

por Burnett, Deborah L., Schofield, Peter, Langley, David B., Jackson, Jennifer, Bourne, Katherine, Wilson, Emily, Porebski, Benjamin T., Buckle, Ashley M., Brink, Robert, Goodnow, Christopher C., Christ, Daniel
Publicado 2020

Genetic and structural basis of the human anti-α-galactosyl antibody response

por Langley, David B., Schofield, Peter, Nevoltris, Damien, Jackson, Jennifer, Jackson, Katherine J. L., Peters, Tim J., Burk, Melanie, Matthews, Jacqueline M., Basten, Antony, Goodnow, Christopher C., van Nunen, Sheryl, Reed, Joanne H., Christ, Daniel
Publicado 2022

Systematic functional identification of cancer multi-drug resistance genes

por Lau, Man-Tat, Ghazanfar, Shila, Parkin, Ashleigh, Chou, Angela, Rouaen, Jourdin R., Littleboy, Jamie B., Nessem, Danielle, Khuong, Thang M., Nevoltris, Damien, Schofield, Peter, Langley, David, Christ, Daniel, Yang, Jean, Pajic, Marina, Neely, G. Gregory
Publicado 2020

Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

por Rouet, Romain, Mazigi, Ohan, Walker, Gregory J., Langley, David B., Sobti, Meghna, Schofield, Peter, Lenthall, Helen, Jackson, Jennifer, Ubiparipovic, Stephanie, Henry, Jake Y., Abayasingam, Arunasingam, Burnett, Deborah, Kelleher, Anthony, Brink, Robert, Bull, Rowena A., Turville, Stuart, Stewart, Alastair G., Goodnow, Christopher C., Rawlinson, William D., Christ, Daniel
Publicado 2021

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

por Lai, Yen-Ting, Wang, Tao, O’Dell, Sijy, Louder, Mark K., Schön, Arne, Cheung, Crystal S. F., Chuang, Gwo-Yu, Druz, Aliaksandr, Lin, Bob, McKee, Krisha, Peng, Dongjun, Yang, Yongping, Zhang, Baoshan, Herschhorn, Alon, Sodroski, Joseph, Bailer, Robert T., Doria-Rose, Nicole A., Mascola, John R., Langley, David R., Kwong, Peter D.
Publicado 2019

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

por Gao, Min, Nettles, Richard E., Belema, Makonen, Snyder, Lawrence B., Nguyen, Van N., Fridell, Robert A., Serrano-Wu, Michael H., Langley, David R., Sun, Jin-Hua, O’Boyle II, Donald R., Lemm, Julie A., Wang, Chunfu, Knipe, Jay O., Chien, Caly, Colonno, Richard J., Grasela, Dennis M., Meanwell, Nicholas A., Hamann, Lawrence G.
Publicado 2010

Crystal structures of trimeric HIV Env with entry inhibitors BMS-378806 and BMS-626529

por Pancera, Marie, Lai, Yen-Ting, Bylund, Tatsiana, Druz, Aliaksandr, Narpala, Sandeep, O’Dell, Sijy, Schön, Arne, Bailer, Robert T., Chuang, Gwo-Yu, Geng, Hui, Louder, Mark K., Rawi, Reda, Soumana, Djade I., Finzi, Andrés, Herschhorn, Alon, Madani, Navid, Sodroski, Joseph, Freire, Ernesto, Langley, David R., Mascola, John R., McDermott, Adrian B., Kwong, Peter D.
Publicado 2017

Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients

por Rouet, Romain, Henry, Jake Y., Johansen, Matt D., Sobti, Meghna, Balachandran, Harikrishnan, Langley, David B., Walker, Gregory J., Lenthall, Helen, Jackson, Jennifer, Ubiparipovic, Stephanie, Mazigi, Ohan, Schofield, Peter, Burnett, Deborah L., Brown, Simon H. J., Martinello, Marianne, Hudson, Bernard, Gilroy, Nicole, Post, Jeffrey J., Kelleher, Anthony, Jäck, Hans-Martin, Goodnow, Christopher C., Turville, Stuart G., Rawlinson, William D., Bull, Rowena A., Stewart, Alastair G., Hansbro, Philip M., Christ, Daniel
Publicado 2023

Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency

por Cagdas, Deniz, Mayr, Daniel, Baris, Safa, Worley, Lisa, Langley, David B., Metin, Ayse, Aytekin, Elif Soyak, Atan, Raziye, Kasap, Nurhan, Bal, Sevgi Köstel, Dmytrus, Jasmin, Heredia, Raul Jimenez, Karasu, Gulsun, Torun, Selda Hancerli, Toyran, Muge, Karakoc-Aydiner, Elif, Christ, Daniel, Kuskonmaz, Baris, Uçkan-Çetinkaya, Duygu, Uner, Aysegul, Oberndorfer, Felicitas, Schiefer, Ana-Iris, Uzel, Gulbu, Deenick, Elissa K., Keller, Baerbel, Warnatz, Klaus, Neven, Bénédicte, Durandy, Anne, Sanal, Ozden, Ma, Cindy S., Özen, Ahmet, Stepensky, Polina, Tezcan, Ilhan, Boztug, Kaan, Tangye, Stuart G.
Publicado 2021