Bayesian optimization with evolutionary and structure-based regularization for directed protein evolution

por Frisby, Trevor S., Langmead, Christopher James
Publicado 2021

Exploring behaviors of stochastic differential equation models of biological systems using change of measures

por Jha, Sumit Kumar, Langmead, Christopher James
Publicado 2012

Asynchronous parallel Bayesian optimization for AI-driven cloud laboratories

por Frisby, Trevor S, Gong, Zhiyun, Langmead, Christopher James
Publicado 2021

Learning generative models of molecular dynamics

por Razavian, Narges Sharif, Kamisetty, Hetunandan, Langmead, Christopher J
Publicado 2012

Unifying cardiovascular modelling with deep reinforcement learning for uncertainty aware control of sepsis treatment

por Nanayakkara, Thesath, Clermont, Gilles, Langmead, Christopher James, Swigon, David
Publicado 2022

Progress in Structure Based Drug Design for G Protein-Coupled Receptors

por Congreve, Miles, Langmead, Christopher J., Mason, Jonathan S., Marshall, Fiona H.
Publicado 2011

A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors

por Moitra, Subhodeep, Tirupula, Kalyan C, Klein-Seetharaman, Judith, Langmead, Christopher James
Publicado 2012

Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics

por Spark, Daisy L., Fornito, Alex, Langmead, Christopher J., Stewart, Gregory D.
Publicado 2022

Efficient Modeling and Active Learning Discovery of Biological Responses

por Naik, Armaghan W., Kangas, Joshua D., Langmead, Christopher J., Murphy, Robert F.
Publicado 2013

Discovering Conformational Sub-States Relevant to Protein Function

por Ramanathan, Arvind, Savol, Andrej J., Langmead, Christopher J., Agarwal, Pratul K., Chennubhotla, Chakra S.
Publicado 2011

Automated parameter estimation for biological models using Bayesian statistical model checking

por Hussain, Faraz, Langmead, Christopher J, Mi, Qi, Dutta-Moscato, Joyeeta, Vodovotz, Yoram, Jha, Sumit K
Publicado 2015

Harvestman: a framework for hierarchical feature learning and selection from whole genome sequencing data

por Frisby, Trevor S., Baker, Shawn J., Marçais, Guillaume, Hoang, Quang Minh, Kingsford, Carl, Langmead, Christopher J.
Publicado 2021

Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research

por Riddy, Darren M., Goy, Emily, Delerive, Philippe, Summers, Roger J., Sexton, Patrick M., Langmead, Christopher J.
Publicado 2018

Does clozapine treat antipsychotic-induced behavioural supersensitivity through glutamate modulation within the striatum?

por Tibrewal, Prashant, Nair, Pramod C., Gregory, Karen J., Langmead, Christopher J., Chan, Sherry Kit Wa, Bastiampillai, Tarun
Publicado 2023

M(1) muscarinic receptor activation decreases alcohol consumption via a reduction in consummatory behavior

por Walker, Leigh C., Campbell, Erin J., Huckstep, Kate L., Chen, Nicola A., Langmead, Christopher J., Lawrence, Andrew J.
Publicado 2021

Agonist-bound adenosine A(2A) receptor structures reveal common features of GPCR activation

por Lebon, Guillaume, Warne, Tony, Edwards, Patricia C., Bennett, Kirstie, Langmead, Christopher J., Leslie, Andrew G.W., Tate, Christopher G.
Publicado 2011

A Novel 5-Cytokine Panel Outperforms Conventional Predictive Markers of Persistent Organ Failure in Acute Pancreatitis

por Langmead, Christopher, Lee, Peter J., Paragomi, Pedram, Greer, Phil, Stello, Kim, Hart, Phil A., Whitcomb, David C., Papachristou, Georgios I.
Publicado 2021

The Marker State Space (MSS) Method for Classifying Clinical Samples

por Fallon, Brian P., Curnutte, Bryan, Maupin, Kevin A., Partyka, Katie, Choi, Sunguk, Brand, Randall E., Langmead, Christopher J., Tembe, Waibhav, Haab, Brian B.
Publicado 2013

Identification of Novel Adenosine A(2A) Receptor Antagonists by Virtual Screening

por Langmead, Christopher J., Andrews, Stephen P., Congreve, Miles, Errey, James C., Hurrell, Edward, Marshall, Fiona H., Mason, Jonathan S., Richardson, Christine M., Robertson, Nathan, Zhukov, Andrei, Weir, Malcolm
Publicado 2012

Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design

por Congreve, Miles, Andrews, Stephen P., Doré, Andrew S., Hollenstein, Kaspar, Hurrell, Edward, Langmead, Christopher J., Mason, Jonathan S., Ng, Irene W., Tehan, Benjamin, Zhukov, Andrei, Weir, Malcolm, Marshall, Fiona H.
Publicado 2012