Helix-helix interaction patterns in membrane proteins

por Langosch, Dieter, Herrmann, Jana R., Unterreitmeier, Stephanie, Fuchs, Angelika
Publicado 2011

Identifying ionic interactions within a membrane using BLaTM, a genetic tool to measure homo- and heterotypic transmembrane helix-helix interactions

por Schanzenbach, Christoph, Schmidt, Fabian C., Breckner, Patrick, Teese, Mark G., Langosch, Dieter
Publicado 2017

Author Correction: Identifying ionic interactions within a membrane using BLaTM, a genetic tool to measure homo- and heterotypic transmembrane helix-helix interactions

por Schanzenbach, Christoph, Schmidt, Fabian C., Breckner, Patrick, Teese, Mark G., Langosch, Dieter
Publicado 2020

Experimental determination and data-driven prediction of homotypic transmembrane domain interfaces

por Xiao, Yao, Zeng, Bo, Berner, Nicola, Frishman, Dmitrij, Langosch, Dieter, Teese, Mark George
Publicado 2020

Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin

por Schmidt, Fabian C., Fitz, Katja, Feilen, Lukas P., Okochi, Masayasu, Steiner, Harald, Langosch, Dieter
Publicado 2023

Increased H-Bond Stability Relates to Altered ε-Cleavage Efficiency and Aβ Levels in the I45T Familial Alzheimer’s Disease Mutant of APP

por Götz, Alexander, Högel, Philipp, Silber, Mara, Chaitoglou, Iro, Luy, Burkhard, Muhle-Goll, Claudia, Scharnagl, Christina, Langosch, Dieter
Publicado 2019

Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase

por Werner, Nadine T., Högel, Philipp, Güner, Gökhan, Stelzer, Walter, Wozny, Manfred, Aßfalg, Marlene, Lichtenthaler, Stefan F., Steiner, Harald, Langosch, Dieter
Publicado 2023

Interaction of Substrates with γ-Secretase at the Level of Individual Transmembrane Helices—A Methodological Approach

por Pauli, Theresa M., Julius, Ayse, Costa, Francesco, Eschrig, Sabine, Moosmüller, Judith, Fischer, Lea, Schanzenbach, Christoph, Schmidt, Fabian C., Ortner, Martin, Langosch, Dieter
Publicado 2023

Non-canonical Shedding of TNFα by SPPL2a Is Determined by the Conformational Flexibility of Its Transmembrane Helix

por Spitz, Charlotte, Schlosser, Christine, Guschtschin-Schmidt, Nadja, Stelzer, Walter, Menig, Simon, Götz, Alexander, Haug-Kröper, Martina, Scharnagl, Christina, Langosch, Dieter, Muhle-Goll, Claudia, Fluhrer, Regina
Publicado 2020

Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage

por Papadopoulou, Alkmini A., Stelzer, Walter, Silber, Mara, Schlosser, Christine, Spitz, Charlotte, Haug-Kröper, Martina, Straub, Tobias, Müller, Stephan A., Lichtenthaler, Stefan F., Muhle-Goll, Claudia, Langosch, Dieter, Fluhrer, Regina
Publicado 2022

Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity

por Güner, Gökhan, Aßfalg, Marlene, Zhao, Kai, Dreyer, Tobias, Lahiri, Shibojyoti, Lo, Yun, Slivinschi, Bianca Ionela, Imhof, Axel, Jocher, Georg, Strohm, Laura, Behrends, Christian, Langosch, Dieter, Bronger, Holger, Nimsky, Christopher, Bartsch, Jörg W, Riddell, Stanley R, Steiner, Harald, Lichtenthaler, Stefan F
Publicado 2022