Addressing Atropisomerism in the Development of Sotorasib, a Covalent Inhibitor of KRAS G12C: Structural, Analytical, and Synthetic Considerations

por Lanman, Brian A., Parsons, Andrew T., Zech, Stephan G.
Publicado 2022

Modeling receptor flexibility in the structure-based design of KRAS(G12C) inhibitors

por Zhu, Kai, Li, Cui, Wu, Kingsley Y., Mohr, Christopher, Li, Xun, Lanman, Brian
Publicado 2022