A computer program for the estimation of protein and nucleic acid sequence diversity in random point mutagenesis libraries

por Volles, Michael J., Lansbury, Peter T.
Publicado 2005

False negatives in GBA1 sequencing due to polymerase dependent allelic imbalance

por den Heijer, Jonas M., Schmitz, Arnoud, Lansbury, Peter, Cullen, Valerie C., Hilt, Dana C., Bonifati, Vincenzo, Groeneveld, Geert Jan
Publicado 2021

Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice

por Cuddy, Leah K., Alia, Alia O., Salvo, Miranda A., Chandra, Sidhanth, Grammatopoulos, Tom N., Justman, Craig J., Lansbury, Peter T., Mazzulli, Joseph R., Vassar, Robert
Publicado 2022

Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors

por Caputo, Samantha, Di Martino, Simona, Cilibrasi, Vincenzo, Tardia, Piero, Mazzonna, Marco, Russo, Debora, Penna, Ilaria, Summa, Maria, Bertozzi, Sine Mandrup, Realini, Natalia, Margaroli, Natasha, Migliore, Marco, Ottonello, Giuliana, Liu, Min, Lansbury, Peter, Armirotti, Andrea, Bertorelli, Rosalia, Ray, Soumya S., Skerlj, Renato, Scarpelli, Rita
Publicado 2020

A randomized single and multiple ascending dose study in healthy volunteers of LTI‐291, a centrally penetrant glucocerebrosidase activator

por den Heijer, Jonas M., Kruithof, Annelieke C., van Amerongen, Guido, de Kam, Marieke L., Thijssen, Eva, Grievink, Hendrika W., Moerland, Matthijs, Walker, Mike, Been, Kees, Skerlj, Renato, Justman, Craig, Dudgeon, Lindsay, Lansbury, Peter, Cullen, Valerie C., Hilt, Dana C., Groeneveld, Geert Jan
Publicado 2021

Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors

por Di Martino, Simona, Tardia, Piero, Cilibrasi, Vincenzo, Caputo, Samantha, Mazzonna, Marco, Russo, Debora, Penna, Ilaria, Realini, Natalia, Margaroli, Natasha, Migliore, Marco, Pizzirani, Daniela, Ottonello, Giuliana, Bertozzi, Sine Mandrup, Armirotti, Andrea, Nguyen, Duc, Sun, Ying, Bongarzone, Ernesto R., Lansbury, Peter, Liu, Min, Skerlj, Renato, Scarpelli, Rita
Publicado 2020

Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease

por Oliveira, Luis M. A., Gasser, Thomas, Edwards, Robert, Zweckstetter, Markus, Melki, Ronald, Stefanis, Leonidas, Lashuel, Hilal A., Sulzer, David, Vekrellis, Kostas, Halliday, Glenda M., Tomlinson, Julianna J., Schlossmacher, Michael, Jensen, Poul Henning, Schulze-Hentrich, Julia, Riess, Olaf, Hirst, Warren D., El-Agnaf, Omar, Mollenhauer, Brit, Lansbury, Peter, Outeiro, Tiago F.
Publicado 2021

A Large‐Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands

por den Heijer, Jonas M., Cullen, Valerie C., Quadri, Marialuisa, Schmitz, Arnoud, Hilt, Dana C., Lansbury, Peter, Berendse, Henk W., van de Berg, Wilma D.J., de Bie, Rob M.A., Boertien, Jeffrey M., Boon, Agnita J.W., Contarino, M. Fiorella, van Hilten, Jacobus J., Hoff, Jorrit I., van Mierlo, Tom, Munts, Alex G., van der Plas, Anne A., Ponsen, Mirthe M., Baas, Frank, Majoor‐Krakauer, Danielle, Bonifati, Vincenzo, van Laar, Teus, Groeneveld, Geert J.
Publicado 2020