Promoters Are Differentially Sensitive to N-Terminal Mutant Huntingtin-Mediated Transcriptional Repression

por Hogel, Matthew, Laprairie, Robert B., Denovan-Wright, Eileen M.
Publicado 2012

Modulation of type 1 cannabinoid receptor activity by cannabinoid by-products from Cannabis sativa and non-cannabis phytomolecules

por Zagzoog, Ayat, Cabecinha, Ashley, Abramovici, Hanan, Laprairie, Robert B.
Publicado 2022

Subfunctionalization of peroxisome proliferator response elements accounts for retention of duplicated fabp1 genes in zebrafish

por Laprairie, Robert B., Denovan-Wright, Eileen M., Wright, Jonathan M.
Publicado 2016

Cannabinoid receptors distribution in mouse cortical plasma membrane compartments

por Miranzadeh Mahabadi, Hajar, Bhatti, Haseeb, Laprairie, Robert B., Taghibiglou, Changiz
Publicado 2021

Estradiol-dependent hypocretinergic/orexinergic behaviors throughout the estrous cycle

por Kim, Hye Ji J., Dickie, Samuel A., Laprairie, Robert B.
Publicado 2022

Components of the endocannabinoid and dopamine systems are dysregulated in Huntington's disease: analysis of publicly available microarray datasets

por Laprairie, Robert B, Bagher, Amina M, Precious, Sophie V, Denovan-Wright, Eileen M
Publicado 2015

Dual Cannabinoid and Orexin Regulation of Anhedonic Behaviour Caused by Prolonged Restraint Stress

por Kim, Hye Ji J., Zagzoog, Ayat, Ceni, Costanza, Ferrisi, Rebecca, Janz, Nicola, Laprairie, Robert B.
Publicado 2023

Impact of the mouse estrus cycle on cannabinoid receptor agonist‐induced molecular and behavioral outcomes

por Kim, Hye Ji J., Zagzoog, Ayat, Black, Tallan, Baccetto, Sarah L., Ezeaka, Udoka C., Laprairie, Robert B.
Publicado 2022

In vivo Evidence for Brain Region-Specific Molecular Interactions Between Cannabinoid and Orexin Receptors

por Kim, Hye Ji J., Zagzoog, Ayat, Smolyakova, Anna Maria, Ezeaka, Udoka C., Benko, Michael J., Holt, Teagan, Laprairie, Robert B.
Publicado 2021

Assessment of select synthetic cannabinoid receptor agonist bias and selectivity between the type 1 and type 2 cannabinoid receptor

por Zagzoog, Ayat, Brandt, Asher L., Black, Tallan, Kim, Eunhyun D., Burkart, Riley, Patel, Mikin, Jin, Zhiyun, Nikolaeva, Maria, Laprairie, Robert B.
Publicado 2021

Indomethacin Enhances Type 1 Cannabinoid Receptor Signaling

por Laprairie, Robert B., Mohamed, Kawthar A., Zagzoog, Ayat, Kelly, Melanie E. M., Stevenson, Lesley A., Pertwee, Roger, Denovan-Wright, Eileen M., Thakur, Ganesh A.
Publicado 2019

In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa

por Zagzoog, Ayat, Mohamed, Kawthar A., Kim, Hye Ji J., Kim, Eunhyun D., Frank, Connor S., Black, Tallan, Jadhav, Pramodkumar D., Holbrook, Larry A., Laprairie, Robert B.
Publicado 2020

Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold

por Ceni, Costanza, Benko, Michael J., Mohamed, Kawthar A., Poli, Giulio, Di Stefano, Miriana, Tuccinardi, Tiziano, Digiacomo, Maria, Valoti, Massimo, Laprairie, Robert B., Macchia, Marco, Bertini, Simone
Publicado 2022

Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593

por Brandt, Asher L., Garai, Sumanta, Zagzoog, Ayat, Hurst, Dow P., Stevenson, Lesley A., Pertwee, Roger G., Imler, Gregory H., Reggio, Patricia H., Thakur, Ganesh A., Laprairie, Robert B.
Publicado 2022

Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB(2)R)

por Ferrisi, Rebecca, Gado, Francesca, Polini, Beatrice, Ricardi, Caterina, Mohamed, Kawthar A., Stevenson, Lesley A., Ortore, Gabriella, Rapposelli, Simona, Saccomanni, Giuseppe, Pertwee, Roger G., Laprairie, Robert B., Manera, Clementina, Chiellini, Grazia
Publicado 2022

Characterization of cannabinoid plasma concentration, maternal health, and cytokine levels in a rat model of prenatal Cannabis smoke exposure

por Black, Tallan, Baccetto, Sarah L., Barnard, Ilne L., Finch, Emma, McElroy, Dan L., Austin-Scott, Faith V. L., Greba, Quentin, Michel, Deborah, Zagzoog, Ayat, Howland, John G., Laprairie, Robert B.
Publicado 2023

The type 1 cannabinoid receptor positive allosteric modulators GAT591 and GAT593 reduce spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg

por McElroy, Dan L., Roebuck, Andrew J., Greba, Quentin, Garai, Sumanta, Brandt, Asher L., Yilmaz, Orhan, Cain, Stuart M., Snutch, Terrance P., Thakur, Ganesh A., Laprairie, Robert B., Howland, John G.
Publicado 2022

Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells

por Gado, Francesca, Ferrisi, Rebecca, Di Somma, Sarah, Napolitano, Fabiana, Mohamed, Kawthar A., Stevenson, Lesley A., Rapposelli, Simona, Saccomanni, Giuseppe, Portella, Giuseppe, Pertwee, Roger G., Laprairie, Robert B., Malfitano, Anna Maria, Manera, Clementina
Publicado 2022

New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2

por Ferrisi, Rebecca, Polini, Beatrice, Ricardi, Caterina, Gado, Francesca, Mohamed, Kawthar A., Baron, Giovanna, Faiella, Salvatore, Poli, Giulio, Rapposelli, Simona, Saccomanni, Giuseppe, Aldini, Giancarlo, Chiellini, Grazia, Laprairie, Robert B., Manera, Clementina, Ortore, Gabriella
Publicado 2023

Repeated Exposure to High-THC Cannabis Smoke during Gestation Alters Sex Ratio, Behavior, and Amygdala Gene Expression of Sprague Dawley Rat Offspring

por Sandini, Thaisa M., Onofrychuk, Timothy J., Roebuck, Andrew J., Hammond, S. Austin, Udenze, Daniel, Hayat, Shahina, Herdzik, Melissa A., McElroy, Dan L., Orvold, Spencer N., Greba, Quentin, Laprairie, Robert B., Howland, John G.
Publicado 2023