Validation of a System x(c)(–) Functional Assay in Cultured Astrocytes and Nervous Tissue Samples

por Beckers, Pauline, Lara, Olaya, Belo do Nascimento, Ines, Desmet, Nathalie, Massie, Ann, Hermans, Emmanuel
Publicado 2022

Nicotinamide combined with gemcitabine is an immunomodulatory therapy that restrains pancreatic cancer in mice

por Selvanesan, Benson Chellakkan, Meena, Kiran, Beck, Amanda, Meheus, Lydie, Lara, Olaya, Rooman, Ilse, Gravekamp, Claudia
Publicado 2020

Chronic Sulfasalazine Treatment in Mice Induces System x(c) (−) - Independent Adverse Effects

por Verbruggen, Lise, Sprimont, Lindsay, Bentea, Eduard, Janssen, Pauline, Gharib, Azzedine, Deneyer, Lauren, De Pauw, Laura, Lara, Olaya, Sato, Hideyo, Nicaise, Charles, Massie, Ann
Publicado 2021

Pancreatic acinar cell fate relies on system x(C)(-) to prevent ferroptosis during stress

por Pan, Zhaolong, Van den Bossche, Jan-Lars, Rodriguez-Aznar, Eva, Janssen, Pauline, Lara, Olaya, Ates, Gamze, Massie, Ann, De Paep, Diedert Luc, Houbracken, Isabelle, Mambretti, Marco, Rooman, Ilse
Publicado 2023

Corticostriatal dysfunction and social interaction deficits in mice lacking the cystine/glutamate antiporter

por Bentea, Eduard, Villers, Agnès, Moore, Cynthia, Funk, Adam J., O’Donovan, Sinead M., Verbruggen, Lise, Lara, Olaya, Janssen, Pauline, De Pauw, Laura, Declerck, Noemi B., DePasquale, Erica A. K., Churchill, Madeline J., Sato, Hideyo, Hermans, Emmanuel, Arckens, Lutgarde, Meshul, Charles K., Ris, Laurence, McCullumsmith, Robert E., Massie, Ann
Publicado 2020

Lifespan extension with preservation of hippocampal function in aged system x(c)(−)-deficient male mice

por Verbruggen, Lise, Ates, Gamze, Lara, Olaya, De Munck, Jolien, Villers, Agnès, De Pauw, Laura, Ottestad-Hansen, Sigrid, Kobayashi, Sho, Beckers, Pauline, Janssen, Pauline, Sato, Hideyo, Zhou, Yun, Hermans, Emmanuel, Njemini, Rose, Arckens, Lutgarde, Danbolt, Niels C., De Bundel, Dimitri, Aerts, Joeri L., Barbé, Kurt, Guillaume, Benoit, Ris, Laurence, Bentea, Eduard, Massie, Ann
Publicado 2022