Haploinsufficiency for Tumor Suppression: The Hazards of Being Single and Living a Long Time

por Largaespada, David A.
Publicado 2001

Generating and manipulating transgenic animals using transposable elements

por Largaespada, David A
Publicado 2003

Transposable elements and the dynamic somatic genome

por Collier, Lara S, Largaespada, David A
Publicado 2007

Transposons for cancer gene discovery: Sleeping Beauty and beyond

por Collier, Lara S, Largaespada, David A
Publicado 2007

Transposon Insertion Mutagenesis in Mice for Modeling Human Cancers: Critical Insights Gained and New Opportunities

por Beckmann, Pauline J., Largaespada, David A.
Publicado 2020

New Model Systems and the Development of Targeted Therapies for the Treatment of Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors

por Williams, Kyle B., Largaespada, David A.
Publicado 2020

Coping with cancer genes altered by copy number

por Wolf, Natalie K., Largaespada, David A., Moriarity, Branden S.
Publicado 2015

Alkylating chemotherapy may exert a uniquely deleterious effect upon neo-antigen-targeting anticancer vaccination

por Litterman, Adam J, Dudek, Arkadiusz Z, Largaespada, David A
Publicado 2013

Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1

por Osum, Sara H., Watson, Adrienne L., Largaespada, David A.
Publicado 2021

Understanding the Osteosarcoma Pathobiology: A Comparative Oncology Approach

por Varshney, Jyotika, Scott, Milcah C., Largaespada, David A., Subramanian, Subbaya
Publicado 2016

Case-oriented pathways analysis in pancreatic adenocarcinoma using data from a sleeping beauty transposon mutagenesis screen

por Ho, Yen-Yi, Starr, Timothy K., LaRue, Rebecca S., Largaespada, David A.
Publicado 2016

Sex differences in expression of immune elements emerge in children, young adults and mice with osteosarcoma

por Mills, Lauren J., Spector, Logan G., Largaespada, David A., Williams, Lindsay A.
Publicado 2021

Flow Assisted Mutation Enrichment (FAME): A highly efficacious and efficient method to enrich Double Knockouts (DKO) after gene editing

por Hansen, Michael, Cai, Xiaopin, Bowen, Sara, Largaespada, David A., Li, Ming V.
Publicado 2021

TAPDANCE: An automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data

por Sarver, Aaron L, Erdman, Jesse, Starr, Tim, Largaespada, David A, Silverstein, Kevin A T
Publicado 2012

Engineered Swine Models of Cancer

por Watson, Adrienne L., Carlson, Daniel F., Largaespada, David A., Hackett, Perry B., Fahrenkrug, Scott C.
Publicado 2016

An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors()

por Patel, Ami V., Chaney, Katherine E., Choi, Kwangmin, Largaespada, David A., Kumar, Ashish R., Ratner, Nancy
Publicado 2016

Doxorubicin Paradoxically Ameliorates Tumor-Induced Inflammation in Young Mice

por Abdelgawad, Ibrahim Y., Grant, Marianne K. O., Popescu, Flavia E., Largaespada, David A., Zordoky, Beshay N.
Publicado 2021

HomeRun Vector Assembly System: A Flexible and Standardized Cloning System for Assembly of Multi-Modular DNA Constructs

por Li, Ming V., Shukla, Dip, Rhodes, Brian H., Lall, Anjali, Shu, Jingmin, Moriarity, Branden S., Largaespada, David A.
Publicado 2014

CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin

por Kendall, Jed J., Chaney, Katherine E., Patel, Ami V., Rizvi, Tilat A., Largaespada, David A., Ratner, Nancy
Publicado 2016

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

por Temiz, Nuri A., Moriarity, Branden S., Wolf, Natalie K., Riordan, Jesse D., Dupuy, Adam J., Largaespada, David A., Sarver, Aaron L.
Publicado 2016