Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs

por Gandhy, Shruti U, Kim, KyoungHyun, Larsen, Lesley, Rosengren, Rhonda J, Safe, Stephen
Publicado 2012

Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: effects on tamoxifen-resistant MCF-7 cancer cells

por Leung, Euphemia, Rewcastle, Gordon W., Joseph, Wayne R., Rosengren, Rhonda J., Larsen, Lesley, Baguley, Bruce C.
Publicado 2011

Norborn-2-en-7-ones as physiologically-triggered carbon monoxide-releasing prodrugs

por Kueh, Jui Thiang Brian, Stanley, Nathan J., Hewitt, Russell J., Woods, Laura M., Larsen, Lesley, Harrison, Joanne C., Rennison, David, Brimble, Margaret A., Sammut, Ivan A., Larsen, David S.
Publicado 2017

A mitochondria-targeted derivative of ascorbate: MitoC

por Finichiu, Peter G., Larsen, David S., Evans, Cameron, Larsen, Lesley, Bright, Thomas P., Robb, Ellen L., Trnka, Jan, Prime, Tracy A., James, Andrew M., Smith, Robin A.J., Murphy, Michael P.
Publicado 2015

Re-Directing an Alkylating Agent to Mitochondria Alters Drug Target and Cell Death Mechanism

por Mourtada, Rida, Fonseca, Sonali B., Wisnovsky, Simon P., Pereira, Mark P., Wang, Xiaoming, Hurren, Rose, Parfitt, Jeremy, Larsen, Lesley, Smith, Robin A. J., Murphy, Michael P., Schimmer, Aaron D., Kelley, Shana O.
Publicado 2013

The Amazon rain forest plant Uncaria tomentosa (cat’s claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles

por Snow, Alan D., Castillo, Gerardo M., Nguyen, Beth P., Choi, Paula Y., Cummings, Joel A., Cam, Judy, Hu, Qubai, Lake, Thomas, Pan, Weihong, Kastin, Abba J., Kirschner, Daniel A., Wood, Steven G., Rockenstein, Edward, Masliah, Eliezer, Lorimer, Stephen, Tanzi, Rudolph E., Larsen, Lesley
Publicado 2019

A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes()

por Pun, Pamela Boon Li, Logan, Angela, Darley-Usmar, Victor, Chacko, Balu, Johnson, Michelle S., Huang, Guang W., Rogatti, Sebastian, Prime, Tracy A., Methner, Carmen, Krieg, Thomas, Fearnley, Ian M., Larsen, Lesley, Larsen, David S., Menger, Katja E., Collins, Yvonne, James, Andrew M., Kumar, G.D. Kishore, Hartley, Richard C., Smith, Robin A.J., Murphy, Michael P.
Publicado 2014