Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model

por Kose, Hazal B., Larsen, Nicolai B., Duxin, Julien P., Yardimci, Hasan
Publicado 2019

Esc2 promotes telomere stability in response to DNA replication stress

por Jørgensen, Signe W, Liberti, Sascha E, Larsen, Nicolai B, Lisby, Michael, Mankouri, Hocine W, Hickson, Ian D
Publicado 2019

Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts

por Larsen, Nicolai B., Gao, Alan O., Sparks, Justin L., Gallina, Irene, Wu, R. Alex, Mann, Matthias, Räschle, Markus, Walter, Johannes C., Duxin, Julien P.
Publicado 2019

Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery

por Krakovka, Sascha, Ranjbarian, Farahnaz, Luján, Lucas A., Saura, Alicia, Larsen, Nicolai B., Jiménez-González, Alejandro, Reggenti, Anna, Luján, Hugo D., Svärd, Staffan G., Hofer, Anders
Publicado 2022

The ubiquitin ligase RFWD3 is required for translesion DNA synthesis

por Gallina, Irene, Hendriks, Ivo A., Hoffmann, Saskia, Larsen, Nicolai B., Johansen, Joachim, Colding-Christensen, Camilla S., Schubert, Lisa, Sellés-Baiget, Selene, Fábián, Zita, Kühbacher, Ulrike, Gao, Alan O., Räschle, Markus, Rasmussen, Simon, Nielsen, Michael L., Mailand, Niels, Duxin, Julien P.
Publicado 2021

Mechanism and function of DNA replication‐independent DNA‐protein crosslink repair via the SUMO‐RNF4 pathway

por Liu, Julio C Y, Kühbacher, Ulrike, Larsen, Nicolai B, Borgermann, Nikoline, Garvanska, Dimitriya H, Hendriks, Ivo A, Ackermann, Leena, Haahr, Peter, Gallina, Irene, Guérillon, Claire, Branigan, Emma, Hay, Ronald T, Azuma, Yoshiaki, Nielsen, Michael Lund, Duxin, Julien P, Mailand, Niels
Publicado 2021