Cdk2: a key regulator of the senescence control function of Myc

por Hydbring, Per, Larsson, Lars-Gunnar
Publicado 2010

MYC Modulation around the CDK2/p27/SKP2 Axis

por Hydbring, Per, Castell, Alina, Larsson, Lars-Gunnar
Publicado 2017

Up-to-date on mortality in COPD - report from the OLIN COPD study

por Lindberg, Anne, Larsson, Lars-Gunnar, Muellerova, Hana, Rönmark, Eva, Lundbäck, Bo
Publicado 2012

MYCN Amplification Is Associated with Reduced Expression of Genes Encoding γ-Secretase Complex and NOTCH Signaling Components in Neuroblastoma

por Agarwal, Prasoon, Glowacka, Aleksandra, Mahmoud, Loay, Bazzar, Wesam, Larsson, Lars-Gunnar, Alzrigat, Mohammad
Publicado 2023

Inhibition of the Intrinsic but Not the Extrinsic Apoptosis Pathway Accelerates and Drives Myc-Driven Tumorigenesis Towards Acute Myeloid Leukemia

por Högstrand, Kari, Hejll, Eduar, Sander, Birgitta, Rozell, Björn, Larsson, Lars-Gunnar, Grandien, Alf
Publicado 2012

Pharmacological inactivation of CDK2 inhibits MYC/BCL-XL-driven leukemia in vivo through induction of cellular senescence

por Bazzar, Wesam, Bocci, Matteo, Hejll, Eduar, Högqvist Tabor, Vedrana, Hydbring, Per, Grandien, Alf, Alzrigat, Mohammad, Larsson, Lars-Gunnar
Publicado 2020

MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts

por Zhang, Fan, Zakaria, Siti Mariam, Högqvist Tabor, Vedrana, Singh, Madhurendra, Tronnersjö, Susanna, Goodwin, Jacob, Selivanova, Galina, Bartek, Jiri, Castell, Alina, Larsson, Lars-Gunnar
Publicado 2018

A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation

por Castell, Alina, Yan, Qinzi, Fawkner, Karin, Hydbring, Per, Zhang, Fan, Verschut, Vasiliki, Franco, Marcela, Zakaria, Siti Mariam, Bazzar, Wesam, Goodwin, Jacob, Zinzalla, Giovanna, Larsson, Lars-Gunnar
Publicado 2018

PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer

por Brunner, Andrä, Suryo Rahmanto, Aldwin, Johansson, Henrik, Franco, Marcela, Viiliäinen, Johanna, Gazi, Mohiuddin, Frings, Oliver, Fredlund, Erik, Spruck, Charles, Lehtiö, Janne, Rantala, Juha K, Larsson, Lars-Gunnar, Sangfelt, Olle
Publicado 2020

Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation

por Bahram, Fuad, Hydbring, Per, Tronnersjö, Susanna, Zakaria, Siti Mariam, Frings, Oliver, Fahlén, Sara, Nilsson, Helén, Goodwin, Jacob, von der Lehr, Natalie, Su, Yingtao, Lüscher, Bernhard, Castell, Alina, Larsson, Lars-Gunnar
Publicado 2015

Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage

por Guerra, Lina, Albihn, Ami, Tronnersjö, Susanna, Yan, Qinzi, Guidi, Riccardo, Stenerlöw, Bo, Sterzenbach, Torsten, Josenhans, Christine, Fox, James G., Schauer, David B., Thelestam, Monica, Larsson, Lars-Gunnar, Henriksson, Marie, Frisan, Teresa
Publicado 2010

HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection

por Liu, Ruining, Muliadi, Victoria, Mou, Wenjun, Li, Hanxiong, Yuan, Juan, Holmberg, Johan, Chambers, Benedict J., Ullah, Nadeem, Wurth, Jakob, Alzrigat, Mohammad, Schlisio, Susanne, Carow, Berit, Larsson, Lars Gunnar, Rottenberg, Martin E.
Publicado 2022

Publisher Correction: HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection

por Liu, Ruining, Muliadi, Victoria, Mou, Wenjun, Li, Hanxiong, Yuan, Juan, Holmberg, Johan, Chambers, Benedict J., Ullah, Nadeem, Wurth, Jakob, Alzrigat, Mohammad, Schlisio, Susanne, Carow, Berit, Larsson, Lars Gunnar, Rottenberg, Martin E.
Publicado 2022

Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule

por Grinkevich, Vera V., Vema, Aparna, Fawkner, Karin, Issaeva, Natalia, Andreotti, Virginia, Dickinson, Eleanor R., Hedström, Elisabeth, Spinnler, Clemens, Inga, Alberto, Larsson, Lars-Gunnar, Karlén, Anders, Wilhelm, Margareta, Barran, Perdita E., Okorokov, Andrei L., Selivanova, Galina, Zawacka-Pankau, Joanna E.
Publicado 2022

MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

por Castell, Alina, Yan, Qinzi, Fawkner, Karin, Bazzar, Wesam, Zhang, Fan, Wickström, Malin, Alzrigat, Mohammad, Franco, Marcela, Krona, Cecilia, Cameron, Donald P., Dyberg, Cecilia, Olsen, Thale Kristin, Verschut, Vasiliki, Schmidt, Linnéa, Lim, Sheryl Y., Mahmoud, Loay, Hydbring, Per, Lehmann, Sören, Baranello, Laura, Nelander, Sven, Johnsen, John Inge, Larsson, Lars-Gunnar
Publicado 2022

MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding

por Massó-Vallés, Daniel, Beaulieu, Marie-Eve, Jauset, Toni, Giuntini, Fabio, Zacarías-Fluck, Mariano F., Foradada, Laia, Martínez-Martín, Sandra, Serrano, Erika, Martín-Fernández, Génesis, Casacuberta-Serra, Sílvia, Castillo Cano, Virginia, Kaur, Jastrinjan, López-Estévez, Sergio, Morcillo, Miguel Ángel, Alzrigat, Mohammad, Mahmoud, Loay, Luque-García, Antonio, Escorihuela, Marta, Guzman, Marta, Arribas, Joaquín, Serra, Violeta, Larsson, Lars-Gunnar, Whitfield, Jonathan R., Soucek, Laura
Publicado 2022

CDK-mediated activation of the SCF(FBXO28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer

por Cepeda, Diana, Ng, Hwee-Fang, Sharifi, Hamid Reza, Mahmoudi, Salah, Cerrato, Vanessa Soto, Fredlund, Erik, Magnusson, Kristina, Nilsson, Helén, Malyukova, Alena, Rantala, Juha, Klevebring, Daniel, Viñals, Francesc, Bhaskaran, Nimesh, Zakaria, Siti Mariam, Rahmanto, Aldwin Suryo, Grotegut, Stefan, Nielsen, Michael Lund, Szigyarto, Cristina Al-Khalili, Sun, Dahui, Lerner, Mikael, Navani, Sanjay, Widschwendter, Martin, Uhlén, Mathias, Jirström, Karin, Pontén, Fredrik, Wohlschlegel, James, Grandér, Dan, Spruck, Charles, Larsson, Lars-Gunnar, Sangfelt, Olle
Publicado 2013