IMMU-01. THE ONCOLYTIC VIRUS DELTA-24-RGD IN COMBINATION WITH AN AGONISTIC CD40 MAB INDUCES A DURABLE AND SYNERGISTIC ANTI-TUMOR IMMUNE EFFECT IN DIPG PRECLINICAL MODELS

por Labiano, Sara, Laspidea, Virginia, Garcia-Moure, Marc, Puigdelloses, Montserrat, Becher, Oren J, Gomez-Manzano, Candelaria, Fueyo, Juan, Patiño-Garcia, Ana, Alonso, Marta M
Publicado 2021

DIPG-10. DELTA-24-RGDOX PROMOTES ANTITUMOR IMMUNE RESPONSE IN DMG MODELS

por Laspidea, Virginia, Ausejo-Mauleon, Iker, de la Nava, Daniel, Nuin, Sara, Hernandez-Osuna, Reyes, Marco-Sanz, Javier, Palacios-Alonso, Daniel, Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta
Publicado 2023

IMMU-06. DELTA-24-RGD EXPRESSING POSITIVE IMMUNE MODULATORS SHOW ANTI-DIPG EFFECT AND INCREASE TUMOR IMMUNE INFILTRATION

por Laspidea, Virginia, Gupta, Sumit, Puigdelloses, Montserrat, Labiano, Sara, Ausejo-Mauleon, Iker, de la Nava, Daniel, Becher, Oren J, Gumin, Joy, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M
Publicado 2021

DIPG-04. TUMOR CELL-INTRINSIC TIM-3 PROMOTES DIFFUSE INTRINSIC PONTINE GLIOMA TUMORIGENESIS

por Ausejo-Mauleon, Iker, Laspidea, Virginia, de la Nava, Daniel, Nuin, Sara, Palacios-Alonso, Daniel, Marco-Sanz, Javier, Becher, Oren, Jiang, Li, Filbon, Mariella G, Pastor, Fernando, Alonso, Marta M
Publicado 2023

IMMU-08. MICROENVIRONMENT MODULATION BY TIM-3 BLOCKADE IMPROVES THE OUTCOME OF PRECLINICAL DIPG MODELS

por Ausejo-Mauleon, Iker, Labiano, Sara, Laspidea, Virginia, Garcia-Moure, Marc, de la Nava, Daniel, Puigdelloses, Montserrat, Becher, Oren J, Jiang, Li, Filbin, Mariella G, Pastor, Fernando, Alonso, Marta M
Publicado 2021

IMMU-18. Targeting Antigen Presenting Cells to improve virotherapy efficacy in Diffuse Midline Gliomas

por Labiano, Sara, Marco-Sanz, Javier, Laspidea, Virginia, Garcia-Moure, Marc, Puigdelloses, Montserrat, Ausejo, Iker, Hernández-Osuna, Reyes, Becher, Oren, Patiño-Garcia, Ana, Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta M
Publicado 2022

THER-01. AWAKING THE IMMUNE SYSTEM WITH AN IMMUNO-ONCOLYTIC VIRUS AS A THERAPEUTIC STRATEGY FOR DIPGs

por Laspidea, Virginia, Puigdelloses, Montse, Ausejo-Mauleon, Iker, Hambardzumyan, Dolores, Chen, Zhihong, Martinez-Velez, Naiara, Zalacain, Marta, de Larraya, Jaime Gallego Perez, Becher, Oren, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M
Publicado 2020

IMMU-09. MODULATING THE MYELOID POPULATION IN DIPG MODELS WITH ONCOLYTIC VIRUS AND COMPLEMENT INHIBITORS SHOWS THERAPEUTIC EFFICACY

por Puigdelloses, Montserrat, Laspidea, Virginia, Hambardzumyan, Dolores, Chen, Zhihong, Gupta, Sumit, Gomez-Manzano, Candelaria, Labiano, Sara, Becher, Oren J, Woodruff, Trent, Pío, Ruben, Ajona, Daniel, Pérez-Larraya, Jaime Gállego, Alonso, Marta M
Publicado 2021

Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma

por Zalacain, Marta, Bunuales, María, Marrodan, Lucía, Labiano, Sara, Gonzalez-Huarriz, Marisol, Martinez-Vélez, Naiara, Laspidea, Virginia, Puigdelloses, Montse, García-Moure, Marc, Gonzalez-Aparicio, Manuela, Hernandez-Alcoceba, Rubén, Alonso, Marta M., Patiño-García, Ana
Publicado 2020

HGG-15. THE IMIPRIDONE ONC201 IN COMBINATION WITH THE ONCOLYTIC ADENOVIRUS DELTA-24-RGD HAS A SYNERGISTIC EFFECT IN PRECLINICAL MODELS OF PHGGS AND DMGS

por de la Nava, Daniel, Ausejo-Mauleon, Iker, Laspidea, Virginia, Marrodán, Lucía, Zalacain, Marta, Herrador-Cañete, Guillermo, Nazarian, Javad, Mueller, Sabine, Allen, Joshua E, Fueyo, Juan, Gomez-Manzano, Candelaria, Gupta, Sumit, Patiño, Ana, Alonso, Marta M
Publicado 2021

Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory

por Martinez-Velez, Naiara, Laspidea, Virginia, Zalacain, Marta, Labiano, Sara, García-Moure, Marc, Puigdelloses, Montse, Marrodan, Lucía, Gonzalez-Huarriz, Marisol, Herrador, Guillermo, de la Nava, Daniel, Ausejo-Mauleon, Iker, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño-García, Ana, Alonso, Marta M.
Publicado 2022

CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models

por Puigdelloses, Montserrat, Garcia-Moure, Marc, Labiano, Sara, Laspidea, Virginia, Gonzalez-Huarriz, Marisol, Zalacain, Marta, Marrodan, Lucia, Martinez-Velez, Naiara, De la Nava, Daniel, Ausejo, Iker, Hervás-Stubbs, Sandra, Herrador, Guillermo, Chen, ZhiHong, Hambardzumyan, Dolores, Patino Garcia, Ana, Jiang, Hong, Gomez-Manzano, Candelaria, Fueyo, Juan, Gállego Pérez-Larraya, Jaime, Alonso, Marta
Publicado 2021

Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma

por Herrador-Cañete, Guillermo, Zalacain, Marta, Labiano, Sara, Laspidea, Virginia, Puigdelloses, Montserrat, Marrodan, Lucía, Garcia-Moure, Marc, Gonzalez-Huarriz, Marisol, Marco-Sanz, Javier, Ausejo-Mauleon, Iker, de la Nava, Daniel, Hernández-Osuna, Reyes, Martínez-García, Javier, Silva-Pilipich, Noelia, Gurucega, Elisabeth, Patiño-García, Ana, Hernández-Alcoceba, Rubén, Smerdou, Cristian, Alonso, Marta M.
Publicado 2022

Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas

por Laspidea, Virginia, Puigdelloses, Montserrat, Labiano, Sara, Marrodán, Lucía, Garcia-Moure, Marc, Zalacain, Marta, Gonzalez-Huarriz, Marisol, Martínez-Vélez, Naiara, Ausejo-Mauleon, Iker, de la Nava, Daniel, Herrador-Cañete, Guillermo, Marco-Sanz, Javier, Guruceaga, Elisabeth, de Andrea, Carlos E., Villalba, María, Becher, Oren, Squatrito, Massimo, Matía, Verónica, Gállego Pérez-Larraya, Jaime, Patiño-García, Ana, Gupta, Sumit, Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta M.
Publicado 2022

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

por Martínez-Vélez, Naiara, Garcia-Moure, Marc, Marigil, Miguel, González-Huarriz, Marisol, Puigdelloses, Montse, Gallego Pérez-Larraya, Jaime, Zalacaín, Marta, Marrodán, Lucía, Varela-Guruceaga, Maider, Laspidea, Virginia, Aristu, Jose Javier, Ramos, Luis Isaac, Tejada-Solís, Sonia, Díez-Valle, Ricardo, Jones, Chris, Mackay, Alan, Martínez-Climent, Jose A., García-Barchino, Maria Jose, Raabe, Eric, Monje, Michelle, Becher, Oren J., Junier, Marie Pierre, El-Habr, Elias A., Chneiweiss, Herve, Aldave, Guillermo, Jiang, Hong, Fueyo, Juan, Patiño-García, Ana, Gomez-Manzano, Candelaria, Alonso, Marta M.
Publicado 2019

TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

por Ausejo-Mauleon, Iker, Labiano, Sara, de la Nava, Daniel, Laspidea, Virginia, Zalacain, Marta, Marrodán, Lucía, García-Moure, Marc, González-Huarriz, Marisol, Hervás-Corpión, Irati, Dhandapani, Laasya, Vicent, Silvestre, Collantes, Maria, Peñuelas, Iván, Becher, Oren J., Filbin, Mariella G., Jiang, Li, Labelle, Jenna, de Biagi-Junior, Carlos A.O., Nazarian, Javad, Laternser, Sandra, Phoenix, Timothy N., van der Lugt, Jasper, Kranendonk, Mariette, Hoogendijk, Raoull, Mueller, Sabine, De Andrea, Carlos, Anderson, Ana C., Guruceaga, Elizabeth, Koschmann, Carl, Yadav, Viveka Nand, Gállego Pérez-Larraya, Jaime, Patiño-García, Ana, Pastor, Fernando, Alonso, Marta M.
Publicado 2023