Is Buffer a Good Proxy for a Crowded Cell-Like Environment? A Comparative NMR Study of Calmodulin Side-Chain Dynamics in Buffer and E. coli Lysate

por Latham, Michael P., Kay, Lewis E.
Publicado 2012

LRET-derived HADDOCK structural models describe the conformational heterogeneity required for DNA cleavage by the Mre11-Rad50 DNA damage repair complex

por Canny, Marella D, Latham, Michael P
Publicado 2022

Biochemical and structural characterization of analogs of MRE11 breast cancer-associated mutant F237C

por Rahman, Samiur, Beikzadeh, Mahtab, Latham, Michael P.
Publicado 2021

Three segment ligation of a 104 kDa multi-domain protein by SrtA and OaAEP1

por Azatian, Stephan B., Canny, Marella D., Latham, Michael P.
Publicado 2022

A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair

por Boswell, Zachary K., Rahman, Samiur, Canny, Marella D., Latham, Michael P.
Publicado 2018

A Survey of Reported Disease-Related Mutations in the MRE11-RAD50-NBS1 Complex

por Rahman, Samiur, Canny, Marella D., Buschmann, Tanner A., Latham, Michael P.
Publicado 2020

The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity

por Grozdanov, Petar N, Masoumzadeh, Elahe, Latham, Michael P, MacDonald, Clinton C
Publicado 2018

Adjacent mutations in the archaeal Rad50 ABC ATPase D-loop disrupt allosteric regulation of ATP hydrolysis through different mechanisms

por Boswell, Zachary K, Canny, Marella D, Buschmann, Tanner A, Sang, Julie, Latham, Michael P
Publicado 2020

Electrostatic Interactions between CSTF2 and pre-mRNA Drive Cleavage and Polyadenylation

por Masoumzadeh, Elahe, Grozdanov, Petar N., Jetly, Anushka, MacDonald, Clinton C., Latham, Michael P.
Publicado 2022

A DNA aptamer reveals an allosteric site for inhibition in metallo-β-lactamases

por Khan, Nazmul H., Bui, Anthony A., Xiao, Yang, Sutton, R. Bryan, Shaw, Robert W., Wylie, Benjamin J., Latham, Michael P.
Publicado 2019

Structural features of Dnase1L3 responsible for serum antigen clearance

por McCord, Jon J., Engavale, Minal, Masoumzadeh, Elahe, Villarreal, Johanna, Mapp, Britney, Latham, Michael P., Keyel, Peter A., Sutton, R. Bryan
Publicado 2022

A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3′ end processing is associated with intellectual disability in h...

por Grozdanov, Petar N, Masoumzadeh, Elahe, Kalscheuer, Vera M, Bienvenu, Thierry, Billuart, Pierre, Delrue, Marie-Ange, Latham, Michael P, MacDonald, Clinton C
Publicado 2020

The Functional Mammalian CRES (Cystatin-Related Epididymal Spermatogenic) Amyloid is Antiparallel β-Sheet Rich and Forms a Metastable Oligomer During Assembly

por Do, Hoa Quynh, Hewetson, Aveline, Myers, Caitlyn, Khan, Nazmul H., Hastert, Mary Catherine, M. Harsini, Faraz, Latham, Michael P., Wylie, Benjamin J., Sutton, R. Bryan, Cornwall, Gail A.
Publicado 2019

How a highly acidic SH3 domain folds in the absence of its charged peptide target

por Jaramillo‐Martinez, Valeria, Dominguez, Matthew J., Bell, Gemma M., Souness, Megan E., Carhart, Anna H., Cuibus, M. Adriana, Masoumzadeh, Elahe, Lantz, Benjamin J., Adkins, Aaron J., Latham, Michael P., Ball, K. Aurelia, Stollar, Elliott J.
Publicado 2023