Non-kinase targeting of oncogenic c-Jun N-terminal kinase (JNK) signaling: the future of clinically viable cancer treatments

por Latham, Sharissa L., O'Donnell, Yolande E.I., Croucher, David R.
Publicado 2022

Cuticle Thickening in a Pyrethroid-Resistant Strain of the Common Bed Bug, Cimex lectularius L. (Hemiptera: Cimicidae)

por Lilly, David G., Latham, Sharissa L., Webb, Cameron E., Doggett, Stephen L.
Publicado 2016

Three mammalian tropomyosin isoforms have different regulatory effects on nonmuscle myosin-2B and filamentous β-actin in vitro

por Pathan-Chhatbar, Salma, Taft, Manuel H., Reindl, Theresia, Hundt, Nikolas, Latham, Sharissa L., Manstein, Dietmar J.
Publicado 2018

A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers

por Filipčík, Pavel, Latham, Sharissa L., Cadell, Antonia L., Day, Catherine L., Croucher, David R., Mace, Peter D.
Publicado 2020

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma

por Phimmachanh, Monica, Han, Jeremy Z. R., O’Donnell, Yolande E. I., Latham, Sharissa L., Croucher, David R.
Publicado 2020

Immuno-analysis of microparticles: probing at the limits of detection

por Latham, Sharissa L., Tiberti, Natalia, Gokoolparsadh, Naveena, Holdaway, Karen, Olivier Couraud, Pierre, Grau, Georges E. R., Combes, Valery
Publicado 2015

The Conserved Lysine-265 Allosterically Modulates Nucleotide- and Actin-binding Site Coupling in Myosin-2

por Behrens, Vincent A., Münnich, Stefan, Adler-Gunzelmann, Georg, Thiel, Claudia, Henn, Arnon, Latham, Sharissa L., Taft, Manuel H.
Publicado 2017

Large-scale production of megakaryocytes in microcarrier-supported stirred suspension bioreactors

por Eicke, Dorothee, Baigger, Anja, Schulze, Kai, Latham, Sharissa L., Halloin, Caroline, Zweigerdt, Robert, Guzman, Carlos A., Blasczyk, Rainer, Figueiredo, Constança
Publicado 2018

Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content

por Tiberti, Natalia, Latham, Sharissa L., Bush, Stephen, Cohen, Amy, Opoka, Robert O., John, Chandy C., Juillard, Annette, Grau, Georges E., Combes, Valéry
Publicado 2016

Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes

por Reindl, Theresia, Giese, Sven, Greve, Johannes N., Reinke, Patrick Y., Chizhov, Igor, Latham, Sharissa L., Mulvihill, Daniel P., Taft, Manuel H., Manstein, Dietmar J.
Publicado 2022

Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

por Hastings, Jordan F, Gonzalez Rajal, Alvaro, Latham, Sharissa L, Han, Jeremy ZR, McCloy, Rachael A, O'Donnell, Yolande EI, Phimmachanh, Monica, Murphy, Alexander D, Nagrial, Adnan, Daneshvar, Dariush, Chin, Venessa, Watkins, D Neil, Burgess, Andrew, Croucher, David R
Publicado 2020

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer

por Kennedy, Sean P., Han, Jeremy Z. R., Portman, Neil, Nobis, Max, Hastings, Jordan F., Murphy, Kendelle J., Latham, Sharissa L., Cadell, Antonia L., Miladinovic, Dushan, Marriott, Gabriella R., O’Donnell, Yolande E. I., Shearer, Robert F., Williams, James T., Munoz, Amaya Garcia, Cox, Thomas R., Watkins, D. Neil, Saunders, Darren N., Timpson, Paul, Lim, Elgene, Kolch, Walter, Croucher, David R.
Publicado 2019

Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia

por Latham, Sharissa L., Ehmke, Nadja, Reinke, Patrick Y. A., Taft, Manuel H., Eicke, Dorothee, Reindl, Theresia, Stenzel, Werner, Lyons, Michael J., Friez, Michael J., Lee, Jennifer A., Hecker, Ramona, Frühwald, Michael C., Becker, Kerstin, Neuhann, Teresa M., Horn, Denise, Schrock, Evelin, Niehaus, Indra, Sarnow, Katharina, Grützmann, Konrad, Gawehn, Luzie, Klink, Barbara, Rump, Andreas, Chaponnier, Christine, Figueiredo, Constanca, Knöfler, Ralf, Manstein, Dietmar J., Di Donato, Nataliya
Publicado 2018

Author Correction: Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia

por Latham, Sharissa L., Ehmke, Nadja, Reinke, Patrick Y. A., Taft, Manuel H., Eicke, Dorothee, Reindl, Theresia, Stenzel, Werner, Lyons, Michael J., Friez, Michael J., Lee, Jennifer A., Hecker, Ramona, Frühwald, Michael C., Becker, Kerstin, Neuhann, Teresa M., Horn, Denise, Schrock, Evelin, Niehaus, Indra, Sarnow, Katharina, Grützmann, Konrad, Gawehn, Luzie, Klink, Barbara, Rump, Andreas, Chaponnier, Christine, Figueiredo, Constanca, Knöfler, Ralf, Manstein, Dietmar J., Di Donato, Nataliya
Publicado 2018

Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma

por Hastings, Jordan F., Latham, Sharissa L., Kamili, Alvin, Wheatley, Madeleine S., Han, Jeremy Z. R., Wong-Erasmus, Marie, Phimmachanh, Monica, Nobis, Max, Pantarelli, Chiara, Cadell, Antonia L., O’Donnell, Yolande E. I., Leong, King Ho, Lynn, Sophie, Geng, Fan-Suo, Cui, Lujing, Yan, Sabrina, Achinger-Kawecka, Joanna, Stirzaker, Clare, Norris, Murray D., Haber, Michelle, Trahair, Toby N., Speleman, Frank, De Preter, Katleen, Cowley, Mark J., Bogdanovic, Ozren, Timpson, Paul, Cox, Thomas R., Kolch, Walter, Fletcher, Jamie I., Fey, Dirk, Croucher, David R.
Publicado 2023

Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse

por Conway, James R. W., Warren, Sean C., Lee, Young-Kyung, McCulloch, Andrew T., Magenau, Astrid, Lee, Victoria, Metcalf, Xanthe L., Stoehr, Janett, Haigh, Katharina, Abdulkhalek, Lea, Guaman, Cristian S., Reed, Daniel A., Murphy, Kendelle J., Pereira, Brooke A., Mélénec, Pauline, Chambers, Cecilia, Latham, Sharissa L., Lenthall, Helen, Deenick, Elissa K., Ma, Yuanqing, Phan, Tri, Lim, Elgene, Joshua, Anthony M., Walters, Stacey, Grey, Shane T., Shi, Yan-Chuan, Zhang, Lei, Herzog, Herbert, Croucher, David R., Philp, Andy, Scheele, Colinda L.G.J., Herrmann, David, Sansom, Owen J., Morton, Jennifer P., Papa, Antonella, Haigh, Jody J., Nobis, Max, Timpson, Paul
Publicado 2023

Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections

por Reinke, Patrick Y. A., de Souza, Edmarcia Elisa, Günther, Sebastian, Falke, Sven, Lieske, Julia, Ewert, Wiebke, Loboda, Jure, Herrmann, Alexander, Rahmani Mashhour, Aida, Karničar, Katarina, Usenik, Aleksandra, Lindič, Nataša, Sekirnik, Andreja, Botosso, Viviane Fongaro, Santelli, Gláucia Maria Machado, Kapronezai, Josana, de Araújo, Marcelo Valdemir, Silva-Pereira, Taiana Tainá, Filho, Antônio Francisco de Souza, Tavares, Mariana Silva, Flórez-Álvarez, Lizdany, de Oliveira, Danielle Bruna Leal, Durigon, Edison Luiz, Giaretta, Paula Roberta, Heinemann, Marcos Bryan, Hauser, Maurice, Seychell, Brandon, Böhler, Hendrik, Rut, Wioletta, Drag, Marcin, Beck, Tobias, Cox, Russell, Chapman, Henry N., Betzel, Christian, Brehm, Wolfgang, Hinrichs, Winfried, Ebert, Gregor, Latham, Sharissa L., Guimarães, Ana Marcia de Sá, Turk, Dusan, Wrenger, Carsten, Meents, Alke
Publicado 2023

A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer

por Chitty, Jessica L., Yam, Michelle, Perryman, Lara, Parker, Amelia L., Skhinas, Joanna N., Setargew, Yordanos F. I., Mok, Ellie T. Y., Tran, Emmi, Grant, Rhiannon D., Latham, Sharissa L., Pereira, Brooke A., Ritchie, Shona C., Murphy, Kendelle J., Trpceski, Michael, Findlay, Alison D., Melenec, Pauline, Filipe, Elysse C., Nadalini, Audrey, Velayuthar, Sipiththa, Major, Gretel, Wyllie, Kaitlin, Papanicolaou, Michael, Ratnaseelan, Shivanjali, Phillips, Phoebe A., Sharbeen, George, Youkhana, Janet, Russo, Alice, Blackwell, Antonia, Hastings, Jordan F., Lucas, Morghan C., Chambers, Cecilia R., Reed, Daniel A., Stoehr, Janett, Vennin, Claire, Pidsley, Ruth, Zaratzian, Anaiis, Da Silva, Andrew M., Tayao, Michael, Charlton, Brett, Herrmann, David, Nobis, Max, Clark, Susan J., Biankin, Andrew V., Johns, Amber L., Croucher, David R., Nagrial, Adnan, Gill, Anthony J., Grimmond, Sean M., Pajic, Marina, Timpson, Paul, Jarolimek, Wolfgang, Cox, Thomas R.
Publicado 2023