Regulation of cytohesins by their interactors in the nervous system

por Zhai, Yuqi, Leung, King To, Lau, Kwok-Fai
Publicado 2023

The roles of atypical protein kinase Cs (aPKCs) in the nervous system: targets for neuroregeneration?

por Chau, Dennis Dik-Long, Lau, Kwok-Fai
Publicado 2020

Phosphorylation of FE65 at threonine 579 by GSK3β stimulates amyloid precursor protein processing

por Lee, Yat Shing, Chow, Wan Ning Vanessa, Lau, Kwok-Fai
Publicado 2017

ARNO is recruited by the neuronal adaptor FE65 to potentiate ARF6-mediated neurite outgrowth

por Zhai, Yuqi, Chan, Wai Wa Ray, Li, Wen, Lau, Kwok-Fai
Publicado 2022

Amyloid precursor protein and its interacting proteins in neurodevelopment

por Chau, Dennis Dik-Long, Ng, Laura Lok-Haang, Zhai, Yuqi, Lau, Kwok-Fai
Publicado 2023

Emerging roles of the neural adaptor FE65 in neurite outgrowth

por Li, Wen, Chan, Wai Wa Ray, Ngo, Jacky Chi Ki, Lau, Kwok-Fai
Publicado 2018

GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer’s disease

por Vivien Chiu, Wai Yin, Koon, Alex Chun, Ki Ngo, Jacky Chi, Edwin Chan, Ho Yin, Lau, Kwok-Fai
Publicado 2017

A Peptidylic Inhibitor for Neutralizing (r)(GGGGCC)(exp)-Associated Neurodegeneration in C9ALS-FTD

por Zhang, Qian, An, Ying, Chen, Zhefan Stephen, Koon, Alex Chun, Lau, Kwok-Fai, Ngo, Jacky Chi Ki, Chan, Ho Yin Edwin
Publicado 2019

Lemur tyrosine kinase-2 signalling regulates kinesin light chain-2 phosphorylation and binding of Smad2 cargo

por Manser, Catherine, Guillot, Florence, Vagnoni, Alessio, Davies, Jennifer, Lau, Kwok-Fai, McLoughlin, Declan M., De Vos, Kurt J., Miller, Christopher C.J.
Publicado 2011

Assessing a peptidylic inhibitor-based therapeutic approach that simultaneously suppresses polyglutamine RNA- and protein-mediated toxicities in patient cells and Drosophila

por Zhang, Qian, Tsoi, Ho, Peng, Shaohong, Li, Pan P., Lau, Kwok-Fai, Rudnicki, Dobrila D., Ngo, Jacky Chi-Ki, Chan, Ho Yin Edwin
Publicado 2016

Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity

por Cheung, Derek Hang-Cheong, Ho, Sai-Tim, Lau, Kwok-Fai, Jin, Rui, Wang, Ya-Nan, Kung, Hsiang-Fu, Huang, Jun-Jian, Shaw, Pang-Chui
Publicado 2017

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

por De Vos, Kurt J., Mórotz, Gábor M., Stoica, Radu, Tudor, Elizabeth L., Lau, Kwok-Fai, Ackerley, Steven, Warley, Alice, Shaw, Christopher E., Miller, Christopher C.J.
Publicado 2012

A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases

por Zhang, Qian, Chen, Zhefan Stephen, An, Ying, Liu, Haizhen, Hou, Yonghui, Li, Wen, Lau, Kwok-Fai, Koon, Alex Chun, Ngo, Jacky Chi Ki, Chan, Ho Yin Edwin
Publicado 2018

Phosphorylation of FE65 Ser(610) by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing

por Chow, Wan Ning Vanessa, Ngo, Jacky Chi Ki, Li, Wen, Chen, Yu Wai, Tam, Ka Ming Vincent, Chan, Ho Yin Edwin, Miller, Christopher C.J., Lau, Kwok-Fai
Publicado 2015

Proteolytic cleavage of amyloid precursor protein by ADAM10 mediates proliferation and migration in breast cancer

por Tsang, Julia Y.S., Lee, Michelle A., Chan, Tsz-Hei, Li, Joshua, Ni, Yun-Bi, Shao, Yan, Chan, Siu-Ki, Cheungc, Sai-Yin, Lau, Kwok-Fai, Tse, Gary M.K.
Publicado 2018

Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627

por Ng, Andy Ka-Leung, Chan, Wai-Hon, Choi, Sze-Ting, Lam, Mandy Ka-Han, Lau, Kwok-Fai, Chan, Paul Kay-Sheung, Au, Shannon Wing-Ngor, Fodor, Ervin, Shaw, Pang-Chui
Publicado 2012

The lysosomal protein cathepsin L is a progranulin protease

por Lee, Chris W., Stankowski, Jeannette N., Chew, Jeannie, Cook, Casey N., Lam, Ying-Wai, Almeida, Sandra, Carlomagno, Yari, Lau, Kwok-Fai, Prudencio, Mercedes, Gao, Fen-Biao, Bogyo, Matthew, Dickson, Dennis W., Petrucelli, Leonard
Publicado 2017

Myriapod genomes reveal ancestral horizontal gene transfer and hormonal gene loss in millipedes

por So, Wai Lok, Nong, Wenyan, Xie, Yichun, Baril, Tobias, Ma, Hai-yao, Qu, Zhe, Haimovitz, Jasmine, Swale, Thomas, Gaitan-Espitia, Juan Diego, Lau, Kwok Fai, Tobe, Stephen S., Bendena, William G., Kai, Zhen-peng, Hayward, Alexander, Hui, Jerome H. L.
Publicado 2022

Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer’s disease

por Iyaswamy, Ashok, Thakur, Abhimanyu, Guan, Xin-Jie, Krishnamoorthi, Senthilkumar, Fung, Tsz Yan, Lu, Kejia, Gaurav, Isha, Yang, Zhijun, Su, Cheng-Fu, Lau, Kwok-Fai, Zhang, Kui, Ng, Roy Chun-Laam, Lian, Qizhou, Cheung, King-Ho, Ye, Keqiang, Chen, Huanhuan Joyce, Li, Min
Publicado 2023

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

por Stoica, Radu, De Vos, Kurt J., Paillusson, Sébastien, Mueller, Sarah, Sancho, Rosa M., Lau, Kwok-Fai, Vizcay-Barrena, Gema, Lin, Wen-Lang, Xu, Ya-Fei, Lewis, Jada, Dickson, Dennis W., Petrucelli, Leonard, Mitchell, Jacqueline C., Shaw, Christopher E., Miller, Christopher C. J.
Publicado 2014