Hepatitis C Virus as a Unique Human Model Disease to Define Differences in the Transcriptional Landscape of T Cells in Acute versus Chronic Infection

por Wolski, David, Lauer, Georg M.
Publicado 2019

Hurdles to the Development of Effective HBV Immunotherapies and HCV Vaccines

por Torres-Cornejo, Almudena, Lauer, Georg M.
Publicado 2017

The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design

por von Delft, Annette, Humphreys, Isla S, Brown, Anthony, Pfafferott, Katja, Lucas, Michaela, Klenerman, Paul, Lauer, Georg M, Cox, Andrea L, Gaudieri, Silvana, Barnes, Eleanor
Publicado 2016

ADCC-Mediated CD56(DIM) NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection

por Yu, Wen-Han, Cosgrove, Cormac, Berger, Christoph T, Cheney, Patrick C, Krykbaeva, Marina, Kim, Arthur Y, Lewis-Ximenez, Lia, Lauer, Georg M, Alter, Galit
Publicado 2018

Chronic HCV Infection Affects the NK Cell Phenotype in the Blood More than in the Liver

por Cosgrove, Cormac, Berger, Christoph T., Kroy, Daniela C., Cheney, Patrick C., Ghebremichael, Musie, Aneja, Jasneet, Tomlinson, Michelle, Kim, Arthur Y., Lauer, Georg M., Alter, Galit
Publicado 2014

Genetic and structural insights into broad neutralization of hepatitis C virus by human V(H)1-69 antibodies

por Tzarum, Netanel, Giang, Erick, Kong, Leopold, He, Linling, Prentoe, Jannick, Augestad, Elias, Hua, Yuanzi, Castillo, Shaun, Lauer, Georg M., Bukh, Jens, Zhu, Jiang, Wilson, Ian A., Law, Mansun
Publicado 2019

Peripheral blood iNKT cell activation correlates with liver damage during acute hepatitis C

por Senff, Tina, Menne, Christopher, Cosmovici, Christine, Lewis-Ximenez, Lia Laura, Aneja, Jasneet, Broering, Ruth, Kim, Arthur Y., Westendorf, Astrid M., Dittmer, Ulf, Scherbaum, Norbert, Lauer, Georg M., Timm, Jörg
Publicado 2022

Precision-Cut Liver Slices as an ex vivo model to evaluate antifibrotic therapies for liver fibrosis and cirrhosis

por Wang, Yongtao, Leaker, Ben, Qiao, Guoliang, Sojoodi, Mozhdeh, Eissa, Ibrahim Ragab, Epstein, Eliana T., Eddy, Jonathan, Dimowo, Oizoshimoshiofu, Lauer, Georg M., Chung, Raymond T., Qadan, Motaz, Lanuti, Michael, Fuchs, Bryan C., Tanabe, Kenneth K.
Publicado 2023

Geographic Differences in Temporal Incidence Trends of Hepatitis C Virus Infection Among People Who Inject Drugs: The InC3 Collaboration

por Morris, Meghan D., Shiboski, Stephen, Bruneau, Julie, Hahn, Judith A., Hellard, Margaret, Prins, Maria, Cox, Andrea L., Dore, Gregory, Grebely, Jason, Kim, Arthur Y., Lauer, Georg M., Lloyd, Andrew, Rice, Thomas, Shoukry, Naglaa, Maher, Lisa, Page, Kimberly
Publicado 2017

Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection

por Kim, Arthur Y, Schulze zur Wiesch, Julian, Kuntzen, Thomas, Timm, Joerg, Kaufmann, Daniel E, Duncan, Jared E, Jones, Andrea M, Wurcel, Alysse G, Davis, Benjamin T, Gandhi, Rajesh T, Robbins, Gregory K, Allen, Todd M, Chung, Raymond T, Lauer, Georg M, Walker, Bruce D
Publicado 2006

CD8 Epitope Escape and Reversion in Acute HCV Infection

por Timm, Joerg, Lauer, Georg M., Kavanagh, Daniel G., Sheridan, Isabelle, Kim, Arthur Y., Lucas, Michaela, Pillay, Thillagavathie, Ouchi, Kei, Reyor, Laura L., zur Wiesch, Julian Schulze, Gandhi, Rajesh T., Chung, Raymond T., Bhardwaj, Nina, Klenerman, Paul, Walker, Bruce D., Allen, Todd M.
Publicado 2004

Broadly directed virus-specific CD4(+) T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

por Schulze zur Wiesch, Julian, Ciuffreda, Donatella, Lewis-Ximenez, Lia, Kasprowicz, Victoria, Nolan, Brian E., Streeck, Hendrik, Aneja, Jasneet, Reyor, Laura L., Allen, Todd M., Lohse, Ansgar W., McGovern, Barbara, Chung, Raymond T., Kwok, William W., Kim, Arthur Y., Lauer, Georg M.
Publicado 2012

CD39 Expression Identifies Terminally Exhausted CD8(+) T Cells

por Gupta, Prakash K., Godec, Jernej, Wolski, David, Adland, Emily, Yates, Kathleen, Pauken, Kristen E., Cosgrove, Cormac, Ledderose, Carola, Junger, Wolfgang G., Robson, Simon C., Wherry, E. John, Alter, Galit, Goulder, Philip J. R., Klenerman, Paul, Sharpe, Arlene H., Lauer, Georg M., Haining, W. Nicholas
Publicado 2015

Peroxidasin Deficiency Re-programs Macrophages Toward Pro-fibrolysis Function and Promotes Collagen Resolution in Liver

por Sojoodi, Mozhdeh, Erstad, Derek J., Barrett, Stephen C., Salloum, Shadi, Zhu, Shijia, Qian, Tongqi, Colon, Selene, Gale, Eric M., Jordan, Veronica Clavijo, Wang, Yongtao, Li, Shen, Ataeinia, Bahar, Jalilifiroozinezhad, Sasan, Lanuti, Michael, Zukerberg, Lawrence, Caravan, Peter, Hoshida, Yujin, Chung, Raymond T., Bhave, Gautam, Lauer, Georg M., Fuchs, Bryan C., Tanabe, Kenneth K.
Publicado 2022

Evolution of the innate and adaptive immune response in women with acute Zika virus infection

por Tonnerre, Pierre, Melgaço, Juliana G, Torres-Cornejo, Almudena, Pinto, Marcelo A, Yue, Constanze, Blümel, Johannes, de Sousa, Paulo Sergio Fonseca, da Motta de Mello, Vinicius, Moran, Julio, de Filippis, Ana M Bispo, Wolski, David, Grifoni, Alba, Sette, Alessandro, Barouch, Dan H, Hoogeveen, Ruben C, Baylis, Sally A, Lauer, Georg M, Lewis-Ximenez, Lia L
Publicado 2019

Distinct Hepatic Gene‐Expression Patterns of NAFLD in Patients With Obesity

por Subudhi, Sonu, Drescher, Hannah K., Dichtel, Laura E., Bartsch, Lea M., Chung, Raymond T., Hutter, Matthew M., Gee, Denise W., Meireles, Ozanan R., Witkowski, Elan R., Gelrud, Louis, Masia, Ricard, Osganian, Stephanie A., Gustafson, Jenna L., Rwema, Steve, Bredella, Miriam A., Bhatia, Sangeeta N., Warren, Andrew, Miller, Karen K., Lauer, Georg M., Corey, Kathleen E.
Publicado 2021

Antibody dynamics and spontaneous viral clearance in patients with acute hepatitis C infection in Rio de Janeiro, Brazil

por Strasak, Alexander M, Kim, Arthur Y, Lauer, Georg M, de Sousa, Paulo S, Ginuino, Cleber F, Fernandes, Carlos A, Velloso, Carlos E, de Almeida, Adilson J, de Oliveira, Jaqueline M, Yoshida, Clara F, zur Wiesch, Julian Schulze, Paranhos-Baccalá, Gláucia, Lang, Stefan, Brant, Larry J, Ulmer, Hanno, Strohmaier, Susanne, Kaltenbach, Lalit, Lampe, Elisabeth, Lewis-Ximenez, Lia L
Publicado 2011

Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection

por Huang, Hailiang, Duggal, Priya, Thio, Chloe L., Latanich, Rachel, Goedert, James J., Mangia, Alessandra, Cox, Andrea L., Kirk, Gregory D., Mehta, Shruti, Aneja, Jasneet, Alric, Laurent, Donfield, Sharyne M., Cramp, Matthew E., Khakoo, Salim I., Tobler, Leslie H., Busch, Michael, Alexander, Graeme J., Rosen, Hugo R., Edlin, Brian R., Segal, Florencia P., Lauer, Georg M., Thomas, David L., Daly, Mark J., Chung, Raymond T., Kim, Arthur Y.
Publicado 2017

Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

por Tonnerre, Pierre, Wolski, David, Subudhi, Sonu, Al-Jabban, Jihad, Hoogeveen, Ruben C., Damasio, Marcos, Drescher, Hannah K., Bartsch, Lea M., Tully, Damien C., Sen, Debattama R., Bean, David J., Brown, Joelle, Torres-Cornejo, Almudena, Robidoux, Maxwell, Kvistad, Daniel, Alatrakchi, Nadia, Cui, Ang, Lieb, David, Cheney, James A., Gustafson, Jenna, Lewis-Ximenez, Lia L, Massenet-Regad, Lucile, Eisenhaure, Thomas, Aneja, Jasneet, Haining, W. Nicholas, Chung, Raymond T., Hacohen, Nir, Allen, Todd M., Kim, Arthur Y., Lauer, Georg M.
Publicado 2021

Multi-ancestry Fine Mapping of Interferon Lambda and the Outcome of Acute Hepatitis C Virus Infection

por Vergara, Candelaria, Duggal, Priya, Thio, Chloe L., Valencia, Ana, O’Brien, Thomas R., Latanich, Rachel, Timp, Winston, Johnson, Eric O., Kral, Alex H., Mangia, Alessandra, Goedert, James J., Piazzola, Valeria, Mehta, Shruti H., Kirk, Gregory D., Peters, Marion G., Donfield, Sharyne M., Edlin, Brian R., Busch, Michael P., Alexander, Graeme, Murphy, Edward L., Kim, Arthur Y., Lauer, Georg M., Chung, Raymond T., Cramp, Matthew E., Cox, Andrea L., Khakoo, Salim I., Rosen, Hugo R., Alric, Laurent, Wheelan, Sarah J., Wojcik, Genevieve L., Thomas, David L., Taub, Margaret A.
Publicado 2020