Rapid Assessment of Homogeneity and Stability of Amorphous Solid Dispersions by Atomic Force Microscopy—From Bench to Batch

por Lauer, Matthias E., Siam, Monira, Tardio, Joseph, Page, Susanne, Kindt, Johannes H., Grassmann, Olaf
Publicado 2013

Nanoindentation of Molecular Crystals: Lessons Learned from Aspirin

por Gabriele, Benjamin P. A., Williams, Craig J., Lauer, Matthias Eckhard, Derby, Brian, Cruz-Cabeza, Aurora J.
Publicado 2020

cryoWriter: a blotting free cryo-EM preparation system with a climate jet and cover-slip injector

por Rima, Luca, Zimmermann, Michael, Fränkl, Andri, Clairfeuille, Thomas, Lauer, Matthias, Engel, Andreas, Engel, Hans-Andreas, Braun, Thomas
Publicado 2022

Cryo-EM structure of alpha-synuclein fibrils

por Guerrero-Ferreira, Ricardo, Taylor, Nicholas MI, Mona, Daniel, Ringler, Philippe, Lauer, Matthias E, Riek, Roland, Britschgi, Markus, Stahlberg, Henning
Publicado 2018

Atomic Force Microscopy-Based Screening of Drug-Excipient Miscibility and Stability of Solid Dispersions

por Lauer, Matthias Eckhard, Grassmann, Olaf, Siam, Monira, Tardio, Joseph, Jacob, Laurence, Page, Susanne, Kindt, Johannes Heinrich, Engel, Andreas, Alsenz, Jochem
Publicado 2010

Generation, Characterization, and Quantitative Bioanalysis of Drug/Anti-drug Antibody Immune Complexes to Facilitate Dedicated In Vivo Studies

por Hoffmann, Eugenia, Jordan, Gregor, Lauer, Matthias, Ringler, Philippe, Kusznir, Eric A., Rufer, Arne C., Huber, Sylwia, Jochner, Anton, Winter, Gerhard, Staack, Roland F.
Publicado 2019

Biochemical and biophysical characterization of purified native CD20 alone and in complex with rituximab and obinutuzumab

por Agez, Morgane, Mandon, Elodie Desuzinges, Iwema, Thomas, Gianotti, Reto, Limani, Florian, Herter, Sylvia, Mössner, Ekkehard, Kusznir, Eric A., Huber, Sylwia, Lauer, Matthias, Ringler, Philippe, Ferrara, Claudia, Klein, Christian, Jawhari, Anass
Publicado 2019

A Miniaturized Extruder to Prototype Amorphous Solid Dispersions: Selection of Plasticizers for Hot Melt Extrusion

por Lauer, Matthias E., Maurer, Reto, De Paepe, Anne T., Stillhart, Cordula, Jacob, Laurence, James, Rajesh, Kojima, Yuki, Rietmann, Rene, Kissling, Tom, van den Ende, Joost A., Schwarz, Sabine, Grassmann, Olaf, Page, Susanne
Publicado 2018

The Contorsbody, an antibody format for agonism: Design, structure, and function

por Georges, Guy J., Dengl, Stefan, Bujotzek, Alexander, Hesse, Friederike, Fischer, Jens A.A., Gärtner, Achim, Benz, Jörg, Lauer, Matthias E., Ringler, Philippe, Stahlberg, Henning, Plath, Friederike, Brinkmann, Ulrich, Imhof-Jung, Sabine
Publicado 2020

Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies

por Dickopf, Steffen, Buldun, Can, Vasic, Vedran, Georges, Guy, Hage, Carina, Mayer, Klaus, Forster, Matthias, Wessels, Uwe, Stubenrauch, Kay-Gunnar, Benz, Jörg, Ehler, Andreas, Lauer, Matthias E., Ringler, Philippe, Kobold, Sebastian, Endres, Stefan, Klein, Christian, Brinkmann, Ulrich
Publicado 2022

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy

por Guerrero-Ferreira, Ricardo, Taylor, Nicholas MI, Arteni, Ana-Andreea, Kumari, Pratibha, Mona, Daniel, Ringler, Philippe, Britschgi, Markus, Lauer, Matthias E, Makky, Ali, Verasdonck, Joeri, Riek, Roland, Melki, Ronald, Meier, Beat H, Böckmann, Anja, Bousset, Luc, Stahlberg, Henning
Publicado 2019

Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles

por Navarro, Paula P., Genoud, Christel, Castaño-Díez, Daniel, Graff-Meyer, Alexandra, Lewis, Amanda J., de Gier, Yvonne, Lauer, Matthias E., Britschgi, Markus, Bohrmann, Bernd, Frank, Stephan, Hench, Jürgen, Schweighauser, Gabriel, Rozemuller, Annemieke J. M., van de Berg, Wilma D. J., Stahlberg, Henning, Shahmoradian, Sarah H.
Publicado 2018

Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody

por Geiger, Martina, Stubenrauch, Kay-Gunnar, Sam, Johannes, Richter, Wolfgang F., Jordan, Gregor, Eckmann, Jan, Hage, Carina, Nicolini, Valeria, Freimoser-Grundschober, Anne, Ritter, Mirko, Lauer, Matthias E., Stahlberg, Henning, Ringler, Philippe, Patel, Jigar, Sullivan, Eric, Grau-Richards, Sandra, Endres, Stefan, Kobold, Sebastian, Umaña, Pablo, Brünker, Peter, Klein, Christian
Publicado 2020

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

por Sustmann, Claudio, Dickopf, Steffen, Regula, Jörg T., Kettenberger, Hubert, Mølhøj, Michael, Gassner, Christian, Weininger, Diana, Fenn, Sebastian, Manigold, Tobias, Kling, Lothar, Künkele, Klaus-Peter, Schwaiger, Manfred, Bossenmaier, Birgit, Griese, Julia J., Hopfner, Karl-Peter, Graff-Meyer, Alexandra, Stahlberg, Henning, Ringler, Philippe, Lauer, Matthias E., Brinkmann, Ulrich, Schaefer, Wolfgang, Klein, Christian
Publicado 2019