Invasive Extravillous Trophoblasts Restrict Intracellular Growth and Spread of Listeria monocytogenes

por Zeldovich, Varvara B., Robbins, Jennifer R., Kapidzic, Mirhan, Lauer, Peter, Bakardjiev, Anna I.
Publicado 2011

Radiation therapy and vaccination against tumor-specific EGFRvIII effectively clears tumors in a murine model of head and neck squamous cell carcinoma

por Uhde, Lauren, Bambina, Shelly, Alice, Alejandro, Lauer, Peter, Crittenden, Marka, Bahjat, Keith S, Gough, Michael
Publicado 2015

Development of mutome-specific personalized vaccines for pancreatic cancer

por Lutz, Eric, Kinkead, Heather, Yager, Allison, Armstrong, Todd, Lauer, Peter, Brockstedt, Dirk, Dubensky, Thomas, Jaffee, Elizabeth
Publicado 2013

Attenuated Listeria monocytogenes reprograms M2-polarized tumor-associated macrophages in ovarian cancer leading to iNOS-mediated tumor cell lysis

por Lizotte, Patrick H, Baird, Jason R, Stevens, Cynthia A, Lauer, Peter, Green, William R, Brockstedt, Dirk G, Fiering, Steven N
Publicado 2014

Dynamic Imaging of the Effector Immune Response to Listeria Infection In Vivo

por Waite, Janelle C., Leiner, Ingrid, Lauer, Peter, Rae, Chris S., Barbet, Gaetan, Zheng, Huan, Portnoy, Daniel A., Pamer, Eric G., Dustin, Michael L.
Publicado 2011

Enhanced Virus-Specific CD8(+) T Cell Responses by Listeria monocytogenes-Infected Dendritic Cells in the Context of Tim-3 Blockade

por Ma, Cheng J., Ren, Jun P., Li, Guang Y., Wu, Xiao Y., Brockstedt, Dirk G., Lauer, Peter, Moorman, Jonathan P., Yao, Zhi Q.
Publicado 2014

A microbial-based cancer vaccine for induction of EGFRvIII-specific CD8+ T cells and anti-tumor immunity

por Zebertavage, Lauren, Bambina, Shelly, Shugart, Jessica, Alice, Alejandro, Zens, Kyra D., Lauer, Peter, Hanson, Bill, Gough, Michael J., Crittenden, Marka R., Bahjat, Keith S.
Publicado 2019

Adhesion to the host cell surface is sufficient to mediate Listeria monocytogenes entry into epithelial cells

por Ortega, Fabian E., Rengarajan, Michelle, Chavez, Natalie, Radhakrishnan, Prathima, Gloerich, Martijn, Bianchini, Julie, Siemers, Kathleen, Luckett, William S., Lauer, Peter, Nelson, W. James, Theriot, Julie A.
Publicado 2017

Phase I study of safety and immunogenicity of ADU-623, a live-attenuated listeria monocytogenes vaccine (ΔactA/ΔinlB) expressing EGFRVIII and NY-ESO-1, in patients with who grade I...

por Crittenden, Marka, Bahjat, Keith S, Li, Rui, Gore, Pankaj, Fountain, Chris, Hanson, Bill, Skoble, Justin, Lauer, Peter, Murphy, Aimee L, Dubensky, Thomas, Brockstedt, Dirk G, Urba, Walter
Publicado 2015

Tumor-Associated Antigen Expressing Listeria monocytogenes Induces Effective Primary and Memory T-Cell Responses Against Hepatic Colorectal Cancer Metastases

por Olino, Kelly, Wada, Satoshi, Edil, Barish H., Pan, Xiaoyu, Meckel, Kristen, Weber, Walter, Slansky, Jill, Tamada, Koji, Lauer, Peter, Brockstedt, Dirk, Pardoll, Drew, Schulick, Richard, Yoshimura, Kiyoshi
Publicado 2011

Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3(+) dendritic cells at cross presentation

por Cohn, Lillian, Chatterjee, Bithi, Esselborn, Filipp, Smed-Sörensen, Anna, Nakamura, Norihiro, Chalouni, Cécile, Lee, Byoung-Chul, Vandlen, Richard, Keler, Tibor, Lauer, Peter, Brockstedt, Dirk, Mellman, Ira, Delamarre, Lélia
Publicado 2013

STING controls T cell memory fitness during infection through T cell-intrinsic and IDO-dependent mechanisms

por Quaney, Michael J., Pritzl, Curtis J., Luera, Dezzarae, Newth, Rebecca J., Knudson, Karin M., Saxena, Vikas, Guldenpfennig, Caitlyn, Gil, Diana, Rae, Chris S., Lauer, Peter, Daniels, Mark A., Teixeiro, Emma
Publicado 2023

Short-term genome evolution of Listeria monocytogenes in a non-controlled environment

por Orsi, Renato H, Borowsky, Mark L, Lauer, Peter, Young, Sarah K, Nusbaum, Chad, Galagan, James E, Birren, Bruce W, Ivy, Reid A, Sun, Qi, Graves, Lewis M, Swaminathan, Bala, Wiedmann, Martin
Publicado 2008

Chromatin states define tumor-specific T cell dysfunction and reprogramming

por Philip, Mary, Fairchild, Lauren, Sun, Liping, Horste, Ellen L., Camara, Steven, Shakiba, Mojdeh, Scott, Andrew C., Viale, Agnes, Lauer, Peter, Merghoub, Taha, Hellmann, Matthew D., Wolchok, Jedd D., Leslie, Christina S., Schietinger, Andrea
Publicado 2017

Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies

por Kim, Victoria M., Blair, Alex B., Lauer, Peter, Foley, Kelly, Che, Xu, Soares, Kevin, Xia, Tao, Muth, Stephen T., Kleponis, Jennifer, Armstrong, Todd D., Wolfgang, Christopher L., Jaffee, Elizabeth M., Brockstedt, Dirk, Zheng, Lei
Publicado 2019

A Potent and Effective Suicidal Listeria Vaccine Platform

por Hanson, William G., Benanti, Erin L., Lemmens, Edward E., Liu, Weiqun, Skoble, Justin, Leong, Meredith L., Rae, Chris S., Fassò, Marcella, Brockstedt, Dirk G., Chen, Chen, Portnoy, Daniel A., Dubensky, Thomas W., Lauer, Peter
Publicado 2019

Modified STING-activating cyclic dinucleotide derivatives significantly enhance the anti-tumor activity of therapeutic vaccines

por Leong, Meredith, Kanne, David, Glickman, Laura, Lemmens, Edward, Lauer, Peter, Metchette, Ken, Burdette, Dara, Diner, Elie, Fu, Juan, Soares, Kevin, Brockstedt, Dirk, Portnoy, Daniel, Vance, Russell, Kim, Young, Jaffee, Elizabeth, Pardoll, Drew, Dubensky, Thomas
Publicado 2013

Recombinant Listeria promotes tumor rejection by CD8(+) T cell-dependent remodeling of the tumor microenvironment

por Deng, Weiwen, Lira, Victor, Hudson, Thomas E., Lemmens, Edward E., Hanson, William G., Flores, Ruben, Barajas, Gonzalo, Katibah, George E., Desbien, Anthony L., Lauer, Peter, Leong, Meredith L., Portnoy, Daniel A., Dubensky, Thomas W.
Publicado 2018

Safety and preliminary immunogenicity of JNJ-64041809, a live-attenuated, double-deleted Listeria monocytogenes-based immunotherapy, in metastatic castration-resistant prostate can...

por Drake, Charles G., Pachynski, Russell K., Subudhi, Sumit K., McNeel, Douglas G., Antonarakis, Emmanuel S., Bauer, Todd M., Lauer, Peter, Brockstedt, Dirk, Patricia, Daniel, Wade, Mark, Zudaire, Enrique, Bandyopadhyay, Nibedita, Parasrampuria, Dolly A., Girgis, Suzette, Mason, Gary E., Knoblauch, Roland E., Stone, Nicole, Infante, Jeffrey R., Gottardis, Marco M., Fong, Lawrence
Publicado 2021

TOX is a critical regulator of tumour-specific T cell differentiation

por Scott, Andrew C., Dündar, Friederike, Zumbo, Paul, Chandran, Smita S., Klebanoff, Christopher A., Shakiba, Mojdeh, Trivedi, Prerak, Menocal, Laura, Appleby, Heather, Camara, Steven, Zamarin, Dmitriy, Walther, tyler, Snyder, Alexandra, Femia, Matthew R., Comen, Elizabeth A., Wen, Hannah Y., Hellmann, Matthew D., Anandasabapathy, Niroshana, Liu, Yong, Altorki, Nasser K., Lauer, Peter, Levy, Olivier, Glickman, Michael S., Kaye, Jonathan, Betel, Doron, Philip, Mary, Schietinger, Andrea
Publicado 2019