AlphaFold 2 and NMR Spectroscopy: Partners to Understand Protein Structure, Dynamics and Function

por Laurents, Douglas V.
Publicado 2022

Do polyproline II helix associations modulate biomolecular condensates?

por Mompeán, Miguel, Oroz, Javier, Laurents, Douglas V.
Publicado 2021

Partial structure, dampened mobility, and modest impact of a His tag in the SARS-CoV-2 Nsp2 C-terminal region

por Mompeán, Miguel, Treviño, Miguel Á., Laurents, Douglas V.
Publicado 2021

Electrostatic Repulsion Governs TDP-43 C-terminal Domain Aggregation

por Mompeán, Miguel, Chakrabartty, Avijit, Buratti, Emanuele, Laurents, Douglas V.
Publicado 2016

An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds

por Mompeán, Miguel, Baralle, Marco, Buratti, Emanuele, Laurents, Douglas V.
Publicado 2016

Structural transitions in Orb2 prion-like domain relevant for functional aggregation in memory consolidation

por Oroz, Javier, Félix, Sara S., Cabrita, Eurico J., Laurents, Douglas V.
Publicado 2021

Fused in sarcoma undergoes cold denaturation: Implications for phase separation

por Félix, Sara S., Laurents, Douglas V., Oroz, Javier, Cabrita, Eurico J.
Publicado 2023

SARS-CoV-2 Nsp8 N-terminal domain folds autonomously and binds dsRNA

por Treviño, Miguel Á, Pantoja-Uceda, David, Laurents, Douglas V, Mompeán, Miguel
Publicado 2023

NMR Characterization of Angiogenin Variants and tRNA(Ala) Products Impacting Aberrant Protein Oligomerization

por Fagagnini, Andrea, Garavís, Miguel, Gómez-Pinto, Irene, Fasoli, Sabrina, Gotte, Giovanni, Laurents, Douglas V.
Publicado 2021

Towards Tricking a Pathogen’s Protease into Fighting Infection: The 3D Structure of a Stable Circularly Permuted Onconase Variant Cleavedby HIV-1 Protease

por Callís, Mariona, Serrano, Soraya, Benito, Antoni, Laurents, Douglas V., Vilanova, Maria, Bruix, Marta, Ribó, Marc
Publicado 2013

Dimerization of Human Angiogenin and of Variants Involved in Neurodegenerative Diseases

por Fasoli, Sabrina, Bettin, Ilaria, Montioli, Riccardo, Fagagnini, Andrea, Peterle, Daniele, Laurents, Douglas V., Gotte, Giovanni
Publicado 2021

Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities

por Gotte, Giovanni, Mahmoud Helmy, Alexander, Ercole, Carmine, Spadaccini, Roberta, Laurents, Douglas V., Donadelli, Massimo, Picone, Delia
Publicado 2012

Phe-Gly motifs drive fibrillization of TDP-43’s prion-like domain condensates

por Pantoja-Uceda, David, Stuani, Cristiana, Laurents, Douglas V., McDermott, Ann E., Buratti, Emanuele, Mompeán, Miguel
Publicado 2021

Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau

por Gracia, Pablo, Polanco, David, Tarancón-Díez, Jorge, Serra, Ilenia, Bracci, Maruan, Oroz, Javier, Laurents, Douglas V., García, Inés, Cremades, Nunilo
Publicado 2022

Metamorphism in TDP-43 prion-like domain determines chaperone recognition

por Carrasco, Jaime, Antón, Rosa, Valbuena, Alejandro, Pantoja-Uceda, David, Mukhi, Mayur, Hervás, Rubén, Laurents, Douglas V., Gasset, María, Oroz, Javier
Publicado 2023

Divergent CPEB prion-like domains reveal different assembly mechanisms for a generic amyloid-like fold

por Hervás, Rubén, del Carmen Fernández-Ramírez, María, Galera-Prat, Albert, Suzuki, Mari, Nagai, Yoshitaka, Bruix, Marta, Menéndez, Margarita, Laurents, Douglas V., Carrión-Vázquez, Mariano
Publicado 2021

Common Features at the Start of the Neurodegeneration Cascade

por Hervás, Rubén, Oroz, Javier, Galera-Prat, Albert, Goñi, Oscar, Valbuena, Alejandro, Vera, Andrés M., Gómez-Sicilia, Àngel, Losada-Urzáiz, Fernando, Uversky, Vladimir N., Menéndez, Margarita, Laurents, Douglas V., Bruix, Marta, Carrión-Vázquez, Mariano
Publicado 2012

Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation

por Hervás, Rubén, Li, Liying, Majumdar, Amitabha, Fernández-Ramírez, María del Carmen, Unruh, Jay R., Slaughter, Brian D., Galera-Prat, Albert, Santana, Elena, Suzuki, Mari, Nagai, Yoshitaka, Bruix, Marta, Casas-Tintó, Sergio, Menéndez, Margarita, Laurents, Douglas V., Si, Kausik, Carrión-Vázquez, Mariano
Publicado 2016