Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon...

por Tikka, Anna, Soronen, Jarkko, Laurila, Pirkka-Pekka, Metso, Jari, Ehnholm, Christian, Jauhiainen, Matti
Publicado 2014

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

por Soronen, Jarkko, Laurila, Pirkka-Pekka, Naukkarinen, Jussi, Surakka, Ida, Ripatti, Samuli, Jauhiainen, Matti, Olkkonen, Vesa M, Yki-Järvinen, Hannele
Publicado 2012

Osbpl8 Deficiency in Mouse Causes an Elevation of High-Density Lipoproteins and Gender-Specific Alterations of Lipid Metabolism

por Béaslas, Olivier, Metso, Jari, Nissilä, Eija, Laurila, Pirkka-Pekka, Kaiharju, Essi, Batchu, Krishna Chaithanya, Kaipiainen, Leena, Mäyränpää, Mikko I., Yan, Daoguang, Gylling, Helena, Jauhiainen, Matti, Olkkonen, Vesa M.
Publicado 2013

Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease

por Soronen, Jarkko, Yki‐Järvinen, Hannele, Zhou, You, Sädevirta, Sanja, Sarin, Antti‐Pekka, Leivonen, Marja, Sevastianova, Ksenia, Perttilä, Julia, Laurila, Pirkka‐Pekka, Sigruener, Alexander, Schmitz, Gerd, Olkkonen, Vesa M.
Publicado 2016

USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages

por Ruuth, Maija, Soronen, Jarkko, Kaiharju, Essi, Merikanto, Krista, Perttilä, Julia, Metso, Jari, Lee-Rueckert, Miriam, Taskinen, Marja-Riitta, Kovanen, Petri T., Öörni, Katariina, Olkkonen, Vesa M., Jauhiainen, Matti S., Laurila, Pirkka-Pekka
Publicado 2018

Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy

por Laurila, Pirkka-Pekka, Luan, Peiling, Wohlwend, Martin, Zanou, Nadège, Crisol, Barbara, Imamura de Lima, Tanes, Goeminne, Ludger J. E., Gallart-Ayala, Hector, Shong, Minho, Ivanisevic, Julijana, Place, Nicolas, Auwerx, Johan
Publicado 2022

Hematopoietic upstream stimulating factor 1 deficiency is associated with increased atherosclerosis susceptibility in LDL receptor knockout mice

por Hoekstra, Menno, Ren, Baoyan, Laurila, Pirkka-Pekka, Hildebrand, Reeni B., Soronen, Jarkko, Frodermann, Vanessa, Li, Zhuang, Boon, Mariëtte R., Geerling, Janine J., Rensen, Patrick C. N., Jauhiainen, Matti, Van Eck, Miranda
Publicado 2021

The Contribution of GWAS Loci in Familial Dyslipidemias

por Ripatti, Pietari, Rämö, Joel T., Söderlund, Sanni, Surakka, Ida, Matikainen, Niina, Pirinen, Matti, Pajukanta, Päivi, Sarin, Antti-Pekka, Service, Susan K., Laurila, Pirkka-Pekka, Ehnholm, Christian, Salomaa, Veikko, Wilson, Richard K., Palotie, Aarno, Freimer, Nelson B., Taskinen, Marja-Riitta, Ripatti, Samuli
Publicado 2016

COX7A2L genetic variants determine cardiorespiratory fitness in mice and human

por Benegiamo, Giorgia, Bou Sleiman, Maroun, Wohlwend, Martin, Rodríguez-López, Sandra, Goeminne, Ludger J. E., Laurila, Pirkka-Pekka, Klevjer, Marie, Salonen, Minna K., Lahti, Jari, Jha, Pooja, Cogliati, Sara, Enriquez, José Antonio, Brumpton, Ben M., Bye, Anja, Eriksson, Johan G., Auwerx, Johan
Publicado 2022

Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis

por Inouye, Michael, Ripatti, Samuli, Kettunen, Johannes, Lyytikäinen, Leo-Pekka, Oksala, Niku, Laurila, Pirkka-Pekka, Kangas, Antti J., Soininen, Pasi, Savolainen, Markku J., Viikari, Jorma, Kähönen, Mika, Perola, Markus, Salomaa, Veikko, Raitakari, Olli, Lehtimäki, Terho, Taskinen, Marja-Riitta, Järvelin, Marjo-Riitta, Ala-Korpela, Mika, Palotie, Aarno, de Bakker, Paul I. W.
Publicado 2012

A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol

por Surakka, Ida, Isaacs, Aaron, Karssen, Lennart C., Laurila, Pirkka-Pekka P., Middelberg, Rita P. S., Tikkanen, Emmi, Ried, Janina S., Lamina, Claudia, Mangino, Massimo, Igl, Wilmar, Hottenga, Jouke-Jan, Lagou, Vasiliki, van der Harst, Pim, Mateo Leach, Irene, Esko, Tõnu, Kutalik, Zoltán, Wainwright, Nicholas W., Struchalin, Maksim V., Sarin, Antti-Pekka, Kangas, Antti J., Viikari, Jorma S., Perola, Markus, Rantanen, Taina, Petersen, Ann-Kristin, Soininen, Pasi, Johansson, Åsa, Soranzo, Nicole, Heath, Andrew C., Papamarkou, Theodore, Prokopenko, Inga, Tönjes, Anke, Kronenberg, Florian, Döring, Angela, Rivadeneira, Fernando, Montgomery, Grant W., Whitfield, John B., Kähönen, Mika, Lehtimäki, Terho, Freimer, Nelson B., Willemsen, Gonneke, de Geus, Eco J. C., Palotie, Aarno, Sandhu, Manj S., Waterworth, Dawn M., Metspalu, Andres, Stumvoll, Michael, Uitterlinden, André G., Jula, Antti, Navis, Gerjan, Wijmenga, Cisca, Wolffenbuttel, Bruce H. R., Taskinen, Marja-Riitta, Ala-Korpela, Mika, Kaprio, Jaakko, Kyvik, Kirsten O., Boomsma, Dorret I., Pedersen, Nancy L., Gyllensten, Ulf, Wilson, James F., Rudan, Igor, Campbell, Harry, Pramstaller, Peter P., Spector, Tim D., Witteman, Jacqueline C. M., Eriksson, Johan G., Salomaa, Veikko, Oostra, Ben A., Raitakari, Olli T., Wichmann, H.-Erich, Gieger, Christian, Järvelin, Marjo-Riitta, Martin, Nicholas G., Hofman, Albert, McCarthy, Mark I., Peltonen, Leena, van Duijn, Cornelia M., Aulchenko, Yurii S., Ripatti, Samuli
Publicado 2011