Epigenetic regulation by RARα maintains ligand-independent transcriptional activity

por Laursen, Kristian B., Wong, Pui-Mun, Gudas, Lorraine J.
Publicado 2012

Polycomb recruitment attenuates retinoic acid–induced transcription of the bivalent NR2F1 gene

por Laursen, Kristian B., Mongan, Nigel P., Zhuang, Yong, Ng, Mary M., Benoit, Yannick D., Gudas, Lorraine J.
Publicado 2013

Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma

por Laursen, Kristian B., Chen, Qiuying, Khani, Francesca, Attarwala, Nabeel, Gross, Steve S., Dow, Lukas, Nanus, David M., Gudas, Lorraine J.
Publicado 2021

MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators

por Nilsson, Emeli M., Laursen, Kristian B., Whitchurch, Jonathan, McWilliam, Andrew, Ødum, Niels, Persson, Jenny L., Heery, David M., Gudas, Lorraine J., Mongan, Nigel P.
Publicado 2015

All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism

por Benjamin, Dalyia N., O’Donovan, Tracey R., Laursen, Kristian B., Orfali, Nina, Cahill, Mary R., Mongan, Nigel P., Gudas, Lorraine J., McKenna, Sharon L.
Publicado 2022

Novel genetically engineered mouse models for clear cell renal cell carcinoma

por van der Mijn, Johannes C., Laursen, Kristian B., Fu, Leiping, Khani, Francesca, Dow, Lukas E., Nowak, Dawid G., Chen, Qiuying, Gross, Steven S., Nanus, David M., Gudas, Lorraine J.
Publicado 2023

NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma

por Kubala, Jaclyn M., Laursen, Kristian B., Schreiner, Ryan, Williams, Ryan M., van der Mijn, Johannes C., Crowley, Michael J., Mongan, Nigel P., Nanus, David M., Heller, Daniel A., Gudas, Lorraine J.
Publicado 2023

The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer

por Metzler, Veronika M., de Brot, Simone, Haigh, Daisy B., Woodcock, Corinne L., Lothion-Roy, Jennifer, Harris, Anna E., Nilsson, Emeli M., Ntekim, Atara, Persson, Jenny L., Robinson, Brian D., Khani, Francesca, Laursen, Kristian B., Gudas, Lorraine J., Toss, Michael S., Madhusudan, Srinivasan, Rakha, Emad, Heery, David M., Rutland, Catrin S., Mongan, Nigel P., Jeyapalan, Jennie N.
Publicado 2023

The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer

por Haigh, Daisy B., Woodcock, Corinne L., Lothion-Roy, Jennifer, Harris, Anna E., Metzler, Veronika M., Persson, Jenny L., Robinson, Brian D., Khani, Francesca, Alsaleem, Mansour, Ntekim, Atara, Madhusudan, Srinivasan, Davis, Melissa B., Laursen, Kristian B., Gudas, Lorraine J., Rutland, Catrin S., Toss, Michael S., Archer, Nathan, Bodi, Zsuzsanna, Rakha, Emad A., Fray, Rupert G., Jeyapalan, Jennie N., Mongan, Nigel P.
Publicado 2022