Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi

por Jensen, Trine I., Mikkelsen, Nanna S., Gao, Zongliang, Foßelteder, Johannes, Pabst, Gabriel, Axelgaard, Esben, Laustsen, Anders, König, Saskia, Reinisch, Andreas, Bak, Rasmus O.
Publicado 2021

Targeted, homology-driven gene insertion in stem cells by ZFN-loaded ‘all-in-one’ lentiviral vectors

por Cai, Yujia, Laustsen, Anders, Zhou, Yan, Sun, Chenglong, Anderson, Mads Valdemar, Li, Shengting, Uldbjerg, Niels, Luo, Yonglun, Jakobsen, Martin R, Mikkelsen, Jacob Giehm
Publicado 2016

Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection

por Egedal, Johanne H., Xie, Guorui, Packard, Thomas A., Laustsen, Anders, Neidleman, Jason, Georgiou, Konstantinos, Pillai, Satish K., Greene, Warner C., Jakobsen, Martin R., Roan, Nadia R.
Publicado 2021

Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells

por Laustsen, Anders, van der Sluis, Renée M, Gris-Oliver, Albert, Hernández, Sabina Sánchez, Cemalovic, Ena, Tang, Hai Q, Pedersen, Lars Henning, Uldbjerg, Niels, Jakobsen, Martin R, Bak, Rasmus O
Publicado 2021

Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells

por Neidleman, Jason A., Chen, Joseph C., Kohgadai, Nargis, Müller, Janis A., Laustsen, Anders, Thavachelvam, Karthiga, Jang, Karen S., Stürzel, Christina M., Jones, Jennifer J., Ochsenbauer, Christina, Chitre, Avantika, Somsouk, Ma, Garcia, Maurice M., Smith, James F., Greenblatt, Ruth M., Münch, Jan, Jakobsen, Martin R., Giudice, Linda C., Greene, Warner C., Roan, Nadia R.
Publicado 2017

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

por Holm, Christian K., Rahbek, Stine H., Gad, Hans Henrik, Bak, Rasmus O., Jakobsen, Martin R., Jiang, Zhaozaho, Hansen, Anne Louise, Jensen, Simon K., Sun, Chenglong, Thomsen, Martin K., Laustsen, Anders, Nielsen, Camilla G., Severinsen, Kasper, Xiong, Yingluo, Burdette, Dara L., Hornung, Veit, Lebbink, Robert Jan, Duch, Mogens, Fitzgerald, Katherine A., Bahrami, Shervin, Mikkelsen, Jakob Giehm, Hartmann, Rune, Paludan, Søren R.
Publicado 2016

TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS‐CoV‐2 infection

por van der Sluis, Renée M, Cham, Lamin B, Gris‐Oliver, Albert, Gammelgaard, Kristine R, Pedersen, Jesper G, Idorn, Manja, Ahmadov, Ulvi, Hernandez, Sabina Sanches, Cémalovic, Ena, Godsk, Stine H, Thyrsted, Jacob, Gunst, Jesper D, Nielsen, Silke D, Jørgensen, Janni J, Bjerg, Tobias Wang, Laustsen, Anders, Reinert, Line S, Olagnier, David, Bak, Rasmus O, Kjolby, Mads, Holm, Christian K, Tolstrup, Martin, Paludan, Søren R, Kristensen, Lasse S, Søgaard, Ole S, Jakobsen, Martin R
Publicado 2022

STEEP mediates STING ER exit and activation of signaling

por Zhang, Bao-cun, Nandakumar, Ramya, Reinert, Line S, Huang, Jinrong, Laustsen, Anders, Gao, Zong-liang, Sun, Cheng-long, Jensen, Søren Beck, Troldborg, Anne, Assil, Sonia, Berthelsen, Martin F., Scavenius, Carsten, Zhang, Yan, Windross, Samuel J, Olagnier, David, Prabakaran, Thaneas, Bodda, Chiranjeevi, Narita, Ryo, Cai, Yujia, Zhang, Cong-gang, Stenmark, Harald, Doucet, Christine M, Noda, Takeshi, Guo, Zheng, Goldbach-Mansky, Raphaela, Hartmann, Rune, Chen, Zhijian J, Enghild, Jan J, Bak, Rasmus O, Thomsen, Martin K., Paludan, Søren R
Publicado 2020

Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming

por Olagnier, David, Brandtoft, Aske M., Gunderstofte, Camilla, Villadsen, Nikolaj L., Krapp, Christian, Thielke, Anne L., Laustsen, Anders, Peri, Suraj, Hansen, Anne Louise, Bonefeld, Lene, Thyrsted, Jacob, Bruun, Victor, Iversen, Marie B., Lin, Lin, Artegoitia, Virginia M., Su, Chenhe, Yang, Long, Lin, Rongtuan, Balachandran, Siddharth, Luo, Yonglun, Nyegaard, Mette, Marrero, Bernadette, Goldbach-Mansky, Raphaela, Motwani, Mona, Ryan, Dylan G., Fitzgerald, Katherine A., O’Neill, Luke A., Hollensen, Anne K., Damgaard, Christian K., de Paoli, Frank v., Bertram, Hanne C., Jakobsen, Martin R., Poulsen, Thomas B., Holm, Christian K.
Publicado 2018