Synovial Tissue: Turning the Page to Precision Medicine in Arthritis

por Triaille, Clément, Lauwerys, Bernard R.
Publicado 2019

Efficacy of anti-IL-1 treatment in familial Mediterranean fever: a systematic review of the literature

por van der Hilst, Jeroen CH, Moutschen, Michel, Messiaen, Peter E, Lauwerys, Bernard R, Vanderschueren, Steven
Publicado 2016

A proteinuria cut-off level of 0.7 g/day after 12 months of treatment best predicts long-term renal outcome in lupus nephritis: data from the MAINTAIN Nephritis Trial

por Tamirou, Farah, Lauwerys, Bernard R, Dall'Era, Maria, Mackay, Meggan, Rovin, Brad, Cervera, Ricard, Houssiau, Frédéric A
Publicado 2015

Common Transcriptomic Effects of Abatacept and Other DMARDs on Rheumatoid Arthritis Synovial Tissue

por Triaille, Clement, Durez, Patrick, Sokolova, Tatiana, Tilman, Gaëlle, Méric de Bellefon, Laurent, Galant, Christine, Coulie, Pierre, Lauwerys, Bernard R., Limaye, Nisha
Publicado 2021

Higher expression of TNFα-induced genes in the synovium of patients with early rheumatoid arthritis correlates with disease activity, and predicts absence of response to first line...

por De Groof, Aurélie, Ducreux, Julie, Humby, Frances, Nzeusseu Toukap, Adrien, Badot, Valérie, Pitzalis, Costantino, Houssiau, Frédéric A., Durez, Patrick, Lauwerys, Bernard R.
Publicado 2016

Overexpression of ubiquitin-specific peptidase 15 in systemic sclerosis fibroblasts increases response to transforming growth factor β

por Galant, Christine, Marchandise, Joel, Stoenoiu, Maria S, Ducreux, Julie, De Groof, Aurélie, Pirenne, Sophie, Van den Eynde, Benoit, Houssiau, Frédéric A, Lauwerys, Bernard R
Publicado 2019

Tapering of biological antirheumatic drugs in rheumatoid arthritis patients is achievable and cost-effective in daily clinical practice: data from the Brussels UCLouvain RA Cohort

por Dierckx, Stéphanie, Sokolova, Tatiana, Lauwerys, Bernard R., Avramovska, Aleksandra, de Bellefon, Laurent Meric, Toukap, Adrien Nzeusseu, Stoenoiu, Maria, Houssiau, Frédéric A., Durez, Patrick
Publicado 2020

Comparative analysis of affected and unaffected areas of systemic sclerosis skin biopsies by high-throughput proteomic approaches

por Chairta, Paraskevi, Nicolaou, Paschalis, Sokratous, Kleitos, Galant, Christine, Houssiau, Frédéric, Oulas, Anastasis, Spyrou, George M., Alarcon-Riquelme, Marta E., Lauwerys, Bernard R., Christodoulou, Kyproula
Publicado 2020

Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis

por Badot, Valérie, Galant, Christine, Nzeusseu Toukap, Adrien, Theate, Ivan, Maudoux, Anne-Lise, Van den Eynde, Benoît J, Durez, Patrick, Houssiau, Frédéric A, Lauwerys, Bernard R
Publicado 2009

Interferon α kinoid induces neutralizing anti-interferon α antibodies that decrease the expression of interferon-induced and B cell activation associated transcripts: analysis of e...

por Ducreux, Julie, Houssiau, Frédéric A., Vandepapelière, Pierre, Jorgensen, Christian, Lazaro, Estibaliz, Spertini, François, Colaone, Fabien, Roucairol, Camille, Laborie, Marion, Croughs, Thérèse, Grouard-Vogel, Géraldine, Lauwerys, Bernard R.
Publicado 2016

Screening for peptides targeted to IL-7Rα for molecular imaging of rheumatoid arthritis synovium

por Burtea, Carmen, Laurent, Sophie, Sanli, Tuba, Fanfone, Deborah, Devalckeneer, Aude, Sauvage, Sébastien, Beckers, Marie-Claire, Rorive, Sandrine, Salmon, Isabelle, Vander Elst, Luce, Lauwerys, Bernard R., Muller, Robert N.
Publicado 2016

Paired Rheumatoid Arthritis Synovial Biopsies From Small and Large Joints Show Similar Global Transcriptomic Patterns With Enrichment of Private Specificity TCRB and TCR Signaling...

por Triaille, Clement, Vansteenkiste, Louise, Constant, Manuel, Ambroise, Jérôme, Méric de Bellefon, Laurent, Nzeusseu Toukap, Adrien, Sokolova, Tatiana, Galant, Christine, Coulie, Pierre, Carrasco, Javier, Durez, Patrick, Lauwerys, Bernard R.
Publicado 2020

Disease activity drives transcriptomic heterogeneity in early untreated rheumatoid synovitis

por Triaille, Clément, Tilman, Gaëlle, Sokolova, Tatiana, Loriot, Axelle, Marchandise, Joelle, De Montjoye, Stéphanie, Nzeusseu-Toukap, Adrien, Méric de Bellefon, Laurent, Bouzin, Caroline, Galant, Christine, Durez, Patrick, Lauwerys, Bernard R, Limaye, Nisha
Publicado 2023

Intrarenal activation of adaptive immune effectors is associated with tubular damage and impaired renal function in lupus nephritis

por Pamfil, Cristina, Makowska, Zuzanna, De Groof, Aurélie, Tilman, Gaëlle, Babaei, Sepideh, Galant, Christine, Montigny, Pauline, Demoulin, Nathalie, Jadoul, Michel, Aydin, Selda, Lesche, Ralf, McDonald, Fiona, Houssiau, Frédéric A, Lauwerys, Bernard R
Publicado 2018

Rapid and Sustained Long‐Term Efficacy and Safety of Canakinumab in Patients With Cryopyrin‐Associated Periodic Syndrome Ages Five Years and Younger

por Brogan, Paul A., Hofer, Michael, Kuemmerle‐Deschner, Jasmin B., Koné‐Paut, Isabelle, Roesler, Joachim, Kallinich, Tilmann, Horneff, Gerd, Calvo Penadés, Inmaculada, Sevilla‐Perez, Belén, Goffin, Laurence, Lauwerys, Bernard R., Lachmann, Helen J., Uziel, Yosef, Wei, Xiaoling, Laxer, Ronald M.
Publicado 2019

Heterogeneity of Synovial Molecular Patterns in Patients with Arthritis

por Lauwerys, Bernard R., Hernández-Lobato, Daniel, Gramme, Pierre, Ducreux, Julie, Dessy, Adrien, Focant, Isabelle, Ambroise, Jérôme, Bearzatto, Bertrand, Nzeusseu Toukap, Adrien, Van den Eynde, Benoît J., Elewaut, Dirk, Gala, Jean-Luc, Durez, Patrick, Houssiau, Frédéric A., Helleputte, Thibault, Dupont, Pierre
Publicado 2015

Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study

por Alonso-Perez, Elisa, Suarez-Gestal, Marian, Calaza, Manuel, Sebastiani, Gian Domenico, Pullmann, Rudolf, Papasteriades, Chryssa, Kovacs, Attila, Skopouli, Fotini N, Bijl, Marc, Suarez, Ana, Marchini, Maurizio, Migliaresi, Sergio, Carreira, Patricia, Ordi-Ros, Josep, Witte, Torsten, Ruzickova, Sarka, Santos, Maria Jose, Barizzone, Nadia, Blanco, Francisco J, Lauwerys, Bernard R, Gomez-Reino, Juan J, Gonzalez, Antonio
Publicado 2012

Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus

por Alonso-Perez, Elisa, Suarez-Gestal, Marian, Calaza, Manuel, Blanco, Francisco J, Suarez, Ana, Santos, Maria Jose, Papasteriades, Chryssa, Carreira, Patricia, Pullmann, Rudolf, Ordi-Ros, Josep, Marchini, Maurizio, Skopouli, Fotini N, Bijl, Marc, Barrizone, Nadia, Sebastiani, Gian Domenico, Migliaresi, Sergio, Witte, Torsten, Lauwerys, Bernard R, Kovacs, Attila, Ruzickova, Sarka, Gomez-Reino, Juan J, Gonzalez, Antonio
Publicado 2014

Further Evidence of Subphenotype Association with Systemic Lupus Erythematosus Susceptibility Loci: A European Cases Only Study

por Alonso-Perez, Elisa, Suarez-Gestal, Marian, Calaza, Manuel, Ordi-Ros, Josep, Balada, Eva, Bijl, Marc, Papasteriades, Chryssa, Carreira, Patricia, Skopouli, Fotini N., Witte, Torsten, Endreffy, Emöke, Marchini, Maurizio, Migliaresi, Sergio, Sebastiani, Gian Domenico, Santos, Maria Jose, Suarez, Ana, Blanco, Francisco J., Barizzone, Nadia, Pullmann, Rudolf, Ruzickova, Sarka, Lauwerys, Bernard R., Gomez-Reino, Juan J., Gonzalez, Antonio
Publicado 2012

Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein

por Delgado-Vega, Angélica M, Dozmorov, Mikhail G, Quirós, Manuel Bernal, Wu, Ying-Yu, Martínez-García, Belén, Kozyrev, Sergey V, Frostegård, Johan, Truedsson, Lennart, de Ramón, Enrique, González-Escribano, María F, Ortego-Centeno, Norberto, Pons-Estel, Bernardo A, D'Alfonso, Sandra, Sebastiani, Gian Domenico, Witte, Torsten, Lauwerys, Bernard R, Endreffy, Emoke, Kovács, László, Vasconcelos, Carlos, da Silva, Berta Martins, Wren, Jonathan D, Martin, Javier, Castillejo-López, Casimiro, Alarcón-Riquelme, Marta E
Publicado 2012