Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach

por Volcho, Konstantin P., Lavrik, Olga I.
Publicado 2023

Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins

por Alemasova, Elizaveta E, Lavrik, Olga I
Publicado 2019

A sePARate phase? Poly(ADP-ribose) versus RNA in the organization of biomolecular condensates

por Alemasova, Elizaveta E, Lavrik, Olga I
Publicado 2022

Poly(ADP-ribose) in Condensates: The PARtnership of Phase Separation and Site-Specific Interactions

por Alemasova, Elizaveta E., Lavrik, Olga I.
Publicado 2022

The Role of PARP1 and PAR in ATP-Independent Nucleosome Reorganisation during the DNA Damage Response

por Belousova, Ekaterina A., Lavrik, Olga I.
Publicado 2022

The XPA Protein—Life under Precise Control

por Krasikova, Yuliya S., Lavrik, Olga I., Rechkunova, Nadejda I.
Publicado 2022

Fused in Sarcoma (FUS) in DNA Repair: Tango with Poly(ADP-ribose) Polymerase 1 and Compartmentalisation of Damaged DNA

por Sukhanova, Maria V., Singatulina, Anastasia S., Pastré, David, Lavrik, Olga I.
Publicado 2020

RPA and XPA interaction with DNA structures mimicking intermediates of the late stages in nucleotide excision repair

por Krasikova, Yuliya S., Rechkunova, Nadejda I., Maltseva, Ekaterina A., Lavrik, Olga I.
Publicado 2018

Apurinic/Apyrimidinic Endonuclease 1 and Tyrosyl-DNA Phosphodiesterase 1 Prevent Suicidal Covalent DNA-Protein Crosslink at Apurinic/Apyrimidinic Site

por Lebedeva, Natalia A., Rechkunova, Nadejda I., Endutkin, Anton V., Lavrik, Olga I.
Publicado 2021

Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites

por Lebedeva, Natalia A., Rechkunova, Nadejda I., El-Khamisy, Sherif F., Lavrik, Olga I.
Publicado 2012

Localization of xeroderma pigmentosum group A protein and replication protein A on damaged DNA in nucleotide excision repair

por Krasikova, Yuliya S., Rechkunova, Nadejda I., Maltseva, Ekaterina A., Petruseva, Irina O., Lavrik, Olga I.
Publicado 2010

FUS Microphase Separation: Regulation by Nucleic Acid Polymers and DNA Repair Proteins

por Sukhanova, Maria V., Anarbaev, Rashid O., Maltseva, Ekaterina A., Pastré, David, Lavrik, Olga I.
Publicado 2022

PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage

por Singatulina, Anastasia S., Sukhanova, Maria V., Desforges, Bénédicte, Joshi, Vandana, Pastré, David, Lavrik, Olga I.
Publicado 2022

The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors

por Alemasova, Elizaveta E., Naumenko, Konstantin N., Kurgina, Tatyana A., Anarbaev, Rashid O., Lavrik, Olga I.
Publicado 2018

PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins

por Savelyev, Nikita V., Shepelev, Nikita M., Lavrik, Olga I., Rubtsova, Maria P., Dontsova, Olga A.
Publicado 2021

Quantitative characterization of protein–protein complexes involved in base excision DNA repair

por Moor, Nina A., Vasil'eva, Inna A., Anarbaev, Rashid O., Antson, Alfred A., Lavrik, Olga I.
Publicado 2015

Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1

por Zakharenko, Alexandra L., Luzina, Olga A., Chepanova, Arina A., Dyrkheeva, Nadezhda S., Salakhutdinov, Nariman F., Lavrik, Olga I.
Publicado 2023

Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System

por Belousova, Ekaterina A., Vasil'eva, Inna A., Moor, Nina A., Zatsepin, Timofey S., Oretskaya, Tatiana S., Lavrik, Olga I.
Publicado 2013

Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase β and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthes...

por Sukhanova, Maria V., Khodyreva, Svetlana N., Lebedeva, Natalia A., Prasad, Rajendra, Wilson, Samuel H., Lavrik, Olga I.
Publicado 2005

Poly(ADP-ribose)polymerase 1 stimulates the AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1

por Lebedeva, Natalia A., Anarbaev, Rashid O., Sukhanova, Maria, Vasil’eva, Inna A., Rechkunova, Nadejda I., Lavrik, Olga I.
Publicado 2015