Transforming growth factor-β induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein

por Brown, Kimberly A, Roberts, Richard L, Arteaga, Carlos L, Law, Brian K
Publicado 2004

NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cel...

por Jaiswal, Aruna S., Panda, Harekrushna, Law, Brian K., Sharma, Jay, Jani, Jitesh, Hromas, Robert, Narayan, Satya
Publicado 2015

Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer

por Al-Awadhi, Fatma H., Salvador, Lilibeth A., Law, Brian K., Paul, Valerie J., Luesch, Hendrik
Publicado 2017

Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line

por Xie, Lu, Law, Brian K, Aakre, Mary E, Edgerton, Mary, Shyr, Yu, Bhowmick, Neil A, Moses, Harold L
Publicado 2003

Signaling Mechanisms that Suppress the Cytostatic Actions of Rapamycin

por Jahn, Stephan C., Law, Mary E., Corsino, Patrick E., Davis, Bradley J., Harrison, Jeffrey K., Law, Brian K.
Publicado 2014

ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

por Narayan, Satya, Ramisetti, Srinivasa, Jaiswal, Aruna S., Law, Brian K., Singh-Pillay, Ashona, Singh, Parvesh, Amin, Shantu, Sharma, Arun K.
Publicado 2019

Inhibition of cotranslational translocation by apratoxin S4: Effects on oncogenic receptor tyrosine kinases and the fate of transmembrane proteins produced in the cytoplasm

por Cai, Weijing, Ratnayake, Ranjala, Wang, Mengxiong, Chen, Qi-Yin, Raisch, Kevin P., Dang, Long H., Law, Brian K., Luesch, Hendrik
Publicado 2021

Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A

por Narayan, Satya, Raza, Asif, Mahmud, Iqbal, Koo, Nayeong, Garrett, Timothy J., Law, Mary E., Law, Brian K., Sharma, Arun K.
Publicado 2022

CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment

por Law, Mary E., Ferreira, Renan B., Davis, Bradley J., Higgins, Paul J., Kim, Jae-Sung, Castellano, Ronald K., Chen, Sixue, Luesch, Hendrik, Law, Brian K.
Publicado 2016

Who Knew? Dopamine Transporter Activity Is Critical in Innate and Adaptive Immune Responses

por Gopinath, Adithya, Mackie, Phillip M., Phan, Leah T., Mirabel, Rosa, Smith, Aidan R., Miller, Emily, Franks, Stephen, Syed, Ohee, Riaz, Tabish, Law, Brian K., Urs, Nikhil, Khoshbouei, Habibeh
Publicado 2023

NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations

por Narayan, Satya, Jaiswal, Aruna S., Sharma, Ritika, Nawab, Akbar, Duckworth, Lizette Vila, Law, Brian K., Zajac-Kaye, Maria, George, Thomas J., Sharma, Jay, Sharma, Arun K., Hromas, Robert A.
Publicado 2017

Repurposing Tranexamic Acid as an Anticancer Agent

por Law, Mary E., Davis, Bradley J., Ghilardi, Amanda F., Yaaghubi, Elham, Dulloo, Zaafir M., Wang, Mengxiong, Guryanova, Olga A., Heldermon, Coy D., Jahn, Stephan C., Castellano, Ronald K., Law, Brian K.
Publicado 2022

Epithelial–Mesenchymal Transition Suppresses AMPK and Sensitizes Cancer Cells to Pyroptosis under Energy Stress

por Liang, Mingwei, Li, Jennifer W., Luo, Huacheng, Lulu, Sarah, Calbay, Ozlem, Shenoy, Anitha, Tan, Ming, Law, Brian K., Huang, Shuang, Xiao, Tsan Sam, Chen, Hao, Wu, Lizi, Chang, Jia, Lu, Jianrong
Publicado 2022

Disulfide bond disrupting agents activate the unfolded protein response in EGFR- and HER2-positive breast tumor cells

por Ferreira, Renan B., Wang, Mengxiong, Law, Mary E., Davis, Bradley J., Bartley, Ashton N., Higgins, Paul J., Kilberg, Michael S., Santostefano, Katherine E., Terada, Naohiro, Heldermon, Coy D., Castellano, Ronald K., Law, Brian K.
Publicado 2017

Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway

por Wang, Mengxiong, Law, Mary E., Davis, Bradley J., Yaaghubi, Elham, Ghilardi, Amanda F., Ferreira, Renan B., Chiang, Chi-Wu, Guryanova, Olga A., Kopinke, Daniel, Heldermon, Coy D., Castellano, Ronald K., Law, Brian K.
Publicado 2019

The B56γ3-containing protein phosphatase 2A attenuates p70S6K-mediated negative feedback loop to enhance AKT-facilitated epithelial-mesenchymal transition in colorectal cancer

por Hsiao, Kai-Ching, Ruan, Siou-Ying, Chen, Shih-Min, Lai, Tai-Yu, Chan, Ren-Hao, Zhang, Yan-Ming, Chu, Chien-An, Cheng, Hung-Chi, Tsai, Hung-Wen, Tu, Yi-Fang, Law, Brian K., Chang, Ting-Tsung, Chow, Nan-Haw, Chiang, Chi-Wu
Publicado 2023

Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers

por Chun, Sung Kook, Lee, Sooyeon, Flores‐Toro, Joseph, U, Rebecca Y., Yang, Ming‐Jim, Go, Kristina L., Biel, Thomas G., Miney, Catherine E., Pierre Louis, Schiley, Law, Brian K., Law, Mary E., Thomas, Elizabeth M., Behrns, Kevin E., Leeuwenburgh, Christiaan, Kim, Jae‐Sung
Publicado 2018

DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

por Venugopal, Kartika, Feng, Yang, Nowialis, Pawel, Xu, Huanzhou, Shabashvili, Daniil E., Berntsen, Cassandra M., Kaur, Prabhjot, Krajcik, Kathryn I., Taragjini, Christina, Zaroogian, Zachary, Casellas Román, Heidi L., Posada, Luisa M., Gunaratne, Chamara, Li, Jianping, Dupéré-Richer, Daphné, Bennett, Richard L., Pondugula, Santhi, Riva, Alberto, Cogle, Christopher R., Opavsky, Rene, Law, Brian K., Bhaduri-McIntosh, Sumita, Kubicek, Stefan, Staber, Philipp B., Licht, Jonathan D., Bird, Jonathan E., Guryanova, Olga A.
Publicado 2022