Tofacitinib as a maintenance therapy in patients with ulcerative colitis stratified by OCTAVE Sustain baseline Mayo endoscopic subscore

por Lee, Scott D., Allegretti, Jessica R., Steinwurz, Flavio, Connelly, Susan B., Lawendy, Nervin, Paulissen, Jerome, Gecse, Krisztina B.
Publicado 2023

The impact of body mass index on efficacy and safety in the tofacitinib OCTAVE ulcerative colitis clinical programme

por Farraye, Francis A., Qazi, Taha, Kotze, Paulo G., Moore, Gregory T., Mundayat, Rajiv, Lawendy, Nervin, Sharma, Puza P., Judd, Donna T.
Publicado 2021

Persistence of treatment in patients with ulcerative colitis who responded to tofacitinib therapy: data from the open‐label, long‐term extension study, OCTAVE open

por Panaccione, Remo, Abreu, Maria T., Lazariciu, Irina, Mundayat, Rajiv, Lawendy, Nervin, Salese, Leonardo, Woolcott, John C., Sands, Bruce E., Chaparro, María
Publicado 2022

Predictors of Sustained Response With Tofacitinib Therapy in Patients With Ulcerative Colitis

por Sandborn, William J, Armuzzi, Alessandro, Liguori, Giuseppina, Irving, Peter M, Sharara, Ala I, Mundayat, Rajiv, Lawendy, Nervin, Woolcott, John C, Danese, Silvio
Publicado 2021

Corticosteroid-free efficacy and safety outcomes in patients receiving tofacitinib in the OCTAVE Sustain maintenance study

por Vavricka, Stephan R., Greuter, Thomas, Cohen, Benjamin L., Reinisch, Walter, Steinwurz, Flavio, Fellmann, Marc, Guo, Xiang, Lawendy, Nervin, Paulissen, Jerome, Peyrin-Biroulet, Laurent
Publicado 2022

Outcomes of Tofacitinib Dose Reduction in Patients with Ulcerative Colitis in Stable Remission from the Randomised RIVETING Trial

por Vermeire, Séverine, Su, Chinyu, Lawendy, Nervin, Kobayashi, Taku, Sandborn, William J, Rubin, David T, Modesto, Irene, Gardiner, Sean, Kulisek, Nicole, Zhang, Haiying, Wang, Wenjin, Panés, Julian
Publicado 2020

Efficacy and Safety of Tofacitinib Re-treatment for Ulcerative Colitis After Treatment Interruption: Results from the OCTAVE Clinical Trials

por Panés, Julian, Vermeire, Séverine, Dubinsky, Marla C, Loftus, Edward V, Lawendy, Nervin, Wang, Wenjin, Salese, Leonardo, Su, Chinyu, Modesto, Irene, Guo, Xiang, Colombel, Jean-Frederic
Publicado 2021

Herpes Zoster Infection in Patients With Ulcerative Colitis Receiving Tofacitinib

por Winthrop, Kevin L, Melmed, Gil Y, Vermeire, Séverine, Long, Millie D, Chan, Gary, Pedersen, Ronald D, Lawendy, Nervin, Thorpe, Andrew J, Nduaka, Chudy I, Su, Chinyu
Publicado 2018

Assessment of Safety and Efficacy of Tofacitinib, Stratified by Age, in Patients from the Ulcerative Colitis Clinical Program

por Lichtenstein, Gary R, Bressler, Brian, Francisconi, Carlos, Vermeire, Severine, Lawendy, Nervin, Salese, Leonardo, Sawyerr, Gosford, Shi, Hongjiong, Su, Chinyu, Judd, Donna T, Jones, Thomas, Loftus, Edward V
Publicado 2022

Venous thromboembolic events in the tofacitinib ulcerative colitis clinical development programme

por Sandborn, William J., Panés, Julian, Sands, Bruce E., Reinisch, Walter, Su, Chinyu, Lawendy, Nervin, Koram, Nana, Fan, Haiyun, Jones, Thomas V., Modesto, Irene, Quirk, Daniel, Danese, Silvio
Publicado 2019

Tofacitinib, an Oral Janus Kinase Inhibitor: Analysis of Malignancy (Excluding Nonmelanoma Skin Cancer) Events Across the Ulcerative Colitis Clinical Program

por Lichtenstein, Gary R, Rogler, Gerhard, Ciorba, Matthew A, Su, Chinyu, Chan, Gary, Pedersen, Ronald D, Lawendy, Nervin, Quirk, Daniel, Nduaka, Chudy I, Thorpe, Andrew J, Panés, Julian
Publicado 2020

Extraintestinal manifestations at baseline, and the effect of tofacitinib, in patients with moderate to severe ulcerative colitis

por Rubin, David T., Reinisch, Walter, Greuter, Thomas, Kotze, Paulo G., Pinheiro, Marcia, Mundayat, Rajiv, Maller, Eric, Fellmann, Marc, Lawendy, Nervin, Modesto, Irene, Vavricka, Stephan R., Lichtenstein, Gary R.
Publicado 2021

Outcomes of Pregnancies With Maternal/Paternal Exposure in the Tofacitinib Safety Databases for Ulcerative Colitis

por Mahadevan, Uma, Dubinsky, Marla C, Su, Chinyu, Lawendy, Nervin, Jones, Thomas V, Marren, Amy, Zhang, Haiying, Graham, Daniela, Clowse, Megan E B, Feldman, Steven R, Baumgart, Daniel C
Publicado 2018

Tofacitinib for the Treatment of Ulcerative Colitis: Analysis of Nonmelanoma Skin Cancer Rates From the Ulcerative Colitis Clinical Program

por Sands, Bruce E, Long, Millie D, Reinisch, Walter, Panés, Julian, Loftus, Edward V, Nduaka, Chudy I, Soonasra, Arif, Mundayat, Rajiv, Lawendy, Nervin, Chan, Gary, Friedman, Gary S, Su, Chinyu
Publicado 2021

Long-term Risk of Herpes Zoster Infection in Patients With Ulcerative Colitis Receiving Tofacitinib

por Winthrop, Kevin L, Vermeire, Séverine, Long, Millie D, Panés, Julian, Ng, Siew C, Kulisek, Nicole, Mundayat, Rajiv, Lawendy, Nervin, Vranic, Ivana, Modesto, Irene, Su, Chinyu, Melmed, Gil Y
Publicado 2022

Tofacitinib for the Treatment of Ulcerative Colitis: Analysis of Infection Rates from the Ulcerative Colitis Clinical Programme

por Winthrop, Kevin L, Loftus, Edward V, Baumgart, Daniel C, Reinisch, Walter, Nduaka, Chudy I, Lawendy, Nervin, Chan, Gary, Mundayat, Rajiv, Friedman, Gary S, Salese, Leonardo, Thorpe, Andrew J, Su, Chinyu
Publicado 2020

Tofacitinib Treatment Safety in Moderate to Severe Ulcerative Colitis: Comparison of Observational Population Cohort Data From the IBM MarketScan® Administrative Claims Database Wi...

por Curtis, Jeffrey R, Regueiro, Miguel, Yun, Huifeng, Su, Chinyu, DiBonaventura, Marco, Lawendy, Nervin, Nduaka, Chudy I, Koram, Nana, Cappelleri, Joseph C, Chan, Gary, Modesto, Irene, Lichtenstein, Gary R
Publicado 2020

Tofacitinib for the Treatment of Ulcerative Colitis: An Integrated Summary of up to 7.8 Years of Safety Data from the Global Clinical Programme

por Sandborn, William J, D’Haens, Geert R, Sands, Bruce E, Panaccione, Remo, Ng, Siew C, Lawendy, Nervin, Kulisek, Nicole, Modesto, Irene, Guo, Xiang, Mundayat, Rajiv, Su, Chinyu, Vranic, Ivana, Panés, Julian
Publicado 2022

Safety and efficacy of tofacitinib for treatment of ulcerative colitis: final analysis of OCTAVE Open, an open‐label, long‐term extension study with up to 7.0 years of treatment...

por Sandborn, William J., Lawendy, Nervin, Danese, Silvio, Su, Chinyu, Loftus, Edward V., Hart, Ailsa, Dotan, Iris, Damião, Adérson O. M. C., Judd, Donna T., Guo, Xiang, Modesto, Irene, Wang, Wenjin, Panés, Julian
Publicado 2021

Efficacy and safety of tofacitinib dose de‐escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open

por Sands, Bruce E., Armuzzi, Alessandro, Marshall, John K., Lindsay, James O., Sandborn, William J., Danese, Silvio, Panés, Julián, Bressler, Brian, Colombel, Jean‐Frédéric, Lawendy, Nervin, Maller, Eric, Zhang, Haiying, Chan, Gary, Salese, Leonardo, Tsilkos, Konstantinos, Marren, Amy, Su, Chinyu
Publicado 2019