HSV-1 Oncolytic Viruses from Bench to Bedside: An Overview of Current Clinical Trials

por Koch, Marilin S., Lawler, Sean E., Chiocca, E. Antonio
Publicado 2020

Modeling Oncolytic Viral Therapy, Immune Checkpoint Inhibition, and the Complex Dynamics of Innate and Adaptive Immunity in Glioblastoma Treatment

por Storey, Kathleen M., Lawler, Sean E., Jackson, Trachette L.
Publicado 2020

The Multifaceted Role of Macrophages in Oncolytic Virotherapy

por Hofman, Laura, Lawler, Sean E., Lamfers, Martine L. M.
Publicado 2021

ABT-263 Enhances Sensitivity to Metformin and 2-Deoxyglucose in Pediatric Glioma by Promoting Apoptotic Cell Death

por Levesley, Jane, Steele, Lynette, Taylor, Claire, Sinha, Priyank, Lawler, Sean E.
Publicado 2013

Proteomic Analysis Implicates Vimentin in Glioblastoma Cell Migration

por Nowicki, Michal O., Hayes, Josie L., Chiocca, E. Antonio, Lawler, Sean E.
Publicado 2019

IM-4 Impact of oHSV activated NOTCH signaling in tumor microenvironment and its impact on anti-tumor immunity

por Yoshihiro, Otani, Yoo, Ji Young, Lawler, Sean E, Chiocca, Antonio E, Kaur, Balveen
Publicado 2021

Metabolic Reprogramming of Glioblastoma Cells during HCMV Infection Induces Secretome-Mediated Paracrine Effects in the Microenvironment

por Harrison, Mark A. A., Hochreiner, Emily M., Benjamin, Brooke P., Lawler, Sean E., Zwezdaryk, Kevin J.
Publicado 2022

BKM-120 (Buparlisib): A Phosphatidyl-Inositol-3 Kinase Inhibitor with Anti-Invasive Properties in Glioblastoma

por Speranza, Maria-Carmela, Nowicki, Michal O., Behera, Prajna, Cho, Choi-Fong, Chiocca, E. Antonio, Lawler, Sean E.
Publicado 2016

Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors

por Zhu, Yanni, Bassoff, Nicole, Reinshagen, Clemens, Bhere, Deepak, Nowicki, Michal O., Lawler, Sean E., Roux, Jérémie, Shah, Khalid
Publicado 2017

Magnetic Resonance Elastography reveals effects of anti-angiogenic glioblastoma treatment on tumor stiffness and captures progression in an orthotopic mouse model

por Schregel, Katharina, Nowicki, Michal O., Palotai, Miklos, Nazari, Navid, Zane, Rachel, Sinkus, Ralph, Lawler, Sean E., Patz, Samuel
Publicado 2020

Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation

por Hayes, Josie, Thygesen, Helene, Droop, Alastair, Hughes, Thomas A., Westhead, David, Lawler, Sean E., Wurdak, Heiko, Short, Susan C.
Publicado 2014

Inflammasome activation: from molecular mechanisms to autoinflammation

por Lara‐Reyna, Samuel, Caseley, Emily A, Topping, Joanne, Rodrigues, François, Jimenez Macias, Jorge, Lawler, Sean E, McDermott, Michael F
Publicado 2022

Uncovering transcriptomic landscape alterations of CAN-2409 in in vitro and in vivo glioma models

por Koch, Marilin S., Zdioruk, Mykola, Nowicki, Michal O., Hoetker, Michael S., Herbert, Zachary T., Barone, Francesca, Tak, Paul P., Chiocca, E. Antonio, Tabatabai, Ghazaleh, Lawler, Sean E.
Publicado 2023

Acetate Supplementation Induces Growth Arrest of NG2/PDGFRα-Positive Oligodendroglioma-Derived Tumor-Initiating Cells

por Long, Patrick M., Tighe, Scott W., Driscoll, Heather E., Moffett, John R., Namboodiri, Aryan M. A., Viapiano, Mariano S., Lawler, Sean E., Jaworski, Diane M.
Publicado 2013

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

por Cho, Choi-Fong, Wolfe, Justin M., Fadzen, Colin M., Calligaris, David, Hornburg, Kalvis, Chiocca, E. Antonio, Agar, Nathalie Y. R., Pentelute, Bradley L., Lawler, Sean E.
Publicado 2017

A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood–Brain Barrier Permeability and Targets Glioblastoma

por Cho, Choi-Fong, Farquhar, Charlotte E., Fadzen, Colin M., Scott, Benjamin, Zhuang, Pei, von Spreckelsen, Niklas, Loas, Andrei, Hartrampf, Nina, Pentelute, Bradley L., Lawler, Sean E.
Publicado 2022

A computationally inspired in-vivo approach identifies a link between amygdalar transcriptional heterogeneity, socialization and anxiety

por Goldman, Aaron, Smalley, Joshua L., Mistry, Meeta, Krenzlin, Harald, Zhang, Hong, Dhawan, Andrew, Caldarone, Barbara, Moss, Stephen J., Silbersweig, David A., Lawler, Sean E., Braun, Ilana M.
Publicado 2019

Drug Resistance in Glioma Cells Induced by a Mesenchymal–Amoeboid Migratory Switch

por Ketchen, Sophie E., Gamboa-Esteves, Filomena O., Lawler, Sean E., Nowicki, Michal O., Rohwedder, Arndt, Knipp, Sabine, Prior, Sally, Short, Susan C., Ladbury, John E., Brüning-Richardson, Anke
Publicado 2021

Erratum: USP11 regulates PML stability to control Notch-induced malignancy in brain tumours

por Wu, Hsin-Chieh, Lin, Yu-Ching, Liu, Cheng-Hsin, Chung, Hsiang-Ching, Wang, Ya-Ting, Lin, Ya-Wen, Ma, Hsin-I., Tu, Pang-Hsien, Lawler, Sean E., Chen, Ruey-Hwa
Publicado 2017

USP11 regulates PML stability to control Notch-induced malignancy in brain tumours

por Wu, Hsin-Chieh, Lin, Yu-Ching, Liu, Cheng-Hsin, Chung, Hsiang-Ching, Wang, Ya-Ting, Lin, Ya-Wen, Ma, Hsin-I., Tu, Pang-Hsien, Lawler, Sean E., Chen, Ruey-Hwa
Publicado 2014