A Phase Ia Study to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 CS Administered Alone and with MVA CS

por de Barra, Eoghan, Hodgson, Susanne H., Ewer, Katie J., Bliss, Carly M., Hennigan, Kerrie, Collins, Ann, Berrie, Eleanor, Lawrie, Alison M., Gilbert, Sarah C., Nicosia, Alfredo, McConkey, Samuel J., Hill, Adrian V. S.
Publicado 2014

Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial

por Manjaly Thomas, Zita-Rose, Satti, Iman, Marshall, Julia L., Harris, Stephanie A., Lopez Ramon, Raquel, Hamidi, Ali, Minhinnick, Alice, Riste, Michael, Stockdale, Lisa, Lawrie, Alison M., Vermaak, Samantha, Wilkie, Morven, Bettinson, Henry, McShane, Helen
Publicado 2019

Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine

por Folegatti, Pedro M., Bellamy, Duncan, Roberts, Rachel, Powlson, Jonathan, Edwards, Nick J., Mair, Catherine F., Bowyer, Georgina, Poulton, Ian, Mitton, Celia H., Green, Nicky, Berrie, Eleanor, Lawrie, Alison M., Hill, Adrian V.S., Ewer, Katie J., Hermon-Taylor, John, Gilbert, Sarah C.
Publicado 2019

Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

por Folegatti, Pedro M., Flaxman, Amy, Jenkin, Daniel, Makinson, Rebecca, Kingham-Page, Lucy, Bellamy, Duncan, Ramos Lopez, Fernando, Sheridan, Jonathan, Poulton, Ian, Aboagye, Jeremy, Tran, Nguyen, Mitton, Celia, Roberts, Rachel, Lawrie, Alison M., Hill, Adrian V. S., Ewer, Katie J., Gilbert, Sarah
Publicado 2021

Safety and immunogenicity of an FP9-vectored candidate tuberculosis vaccine (FP85A), alone and with candidate vaccine MVA85A in BCG-vaccinated healthy adults: A phase I clinical tr...

por Rowland, Rosalind, Pathan, Ansar A., Satti, Iman, Poulton, Ian D., Matsumiya, Magali M. L., Whittaker, Megan, Minassian, Angela M., O’Hara, Geraldine A., Hamill, Matthew, Scott, Janet T., Harris, Stephanie A., Poyntz, Hazel C., Bateman, Cynthia, Meyer, Joel, Williams, Nicola, Gilbert, Sarah C., Lawrie, Alison M., Hill, Adrian V.S., McShane, Helen
Publicado 2013

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe

por Sheehy, Susanne H., Spencer, Alexandra J., Douglas, Alexander D., Sim, B. Kim Lee, Longley, Rhea J., Edwards, Nick J., Poulton, Ian D., Kimani, Domtila, Williams, Andrew R., Anagnostou, Nicholas A., Roberts, Rachel, Kerridge, Simon, Voysey, Merryn, James, Eric R., Billingsley, Peter F., Gunasekera, Anusha, Lawrie, Alison M., Hoffman, Stephen L., Hill, Adrian V. S.
Publicado 2013

Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP

por Bliss, Carly M., Bowyer, Georgina, Anagnostou, Nicholas A., Havelock, Tom, Snudden, Claudia M., Davies, Huw, de Cassan, Simone C., Grobbelaar, Amy, Lawrie, Alison M., Venkatraman, Navin, Poulton, Ian D., Roberts, Rachel, Mange, Pooja B., Choudhary, Prateek, Faust, Saul N., Colloca, Stefano, Gilbert, Sarah C., Nicosia, Alfredo, Hill, Adrian V. S., Ewer, Katie J.
Publicado 2018

Combining Viral Vectored and Protein-in-adjuvant Vaccines Against the Blood-stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial

por Hodgson, Susanne H, Choudhary, Prateek, Elias, Sean C, Milne, Kathryn H, Rampling, Thomas W, Biswas, Sumi, Poulton, Ian D, Miura, Kazutoyo, Douglas, Alexander D, Alanine, Daniel GW, Illingworth, Joseph J, de Cassan, Simone C, Zhu, Daming, Nicosia, Alfredo, Long, Carole A, Moyle, Sarah, Berrie, Eleanor, Lawrie, Alison M, Wu, Yimin, Ellis, Ruth D, Hill, Adrian V S, Draper, Simon J
Publicado 2014

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal

por Mensah, Victorine A., Gueye, Aly, Ndiaye, Magatte, Edwards, Nick J., Wright, Danny, Anagnostou, Nicholas A., Syll, Massamba, Ndaw, Amy, Abiola, Annie, Bliss, Carly, Gomis, Jules-François, Petersen, Ines, Ogwang, Caroline, Dieye, Tandakha, Viebig, Nicola K., Lawrie, Alison M., Roberts, Rachel, Nicosia, Alfredo, Faye, Babacar, Gaye, Oumar, Leroy, Odile, Imoukhuede, Egeruan B., Ewer, Katie J., Bejon, Philip, Hill, Adrian V. S., Cisse, Badara
Publicado 2016

Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial

por Mensah, Victorine A., Roetynck, Sophie, Kanteh, Ebrima K., Bowyer, Georgina, Ndaw, Amy, Oko, Francis, Bliss, Carly M., Jagne, Ya Jankey, Cortese, Riccardo, Nicosia, Alfredo, Roberts, Rachel, D’Alessio, Flavia, Leroy, Odile, Faye, Babacar, Kampmann, Beate, Cisse, Badara, Bojang, Kalifa, Gerry, Stephen, Viebig, Nicola K., Lawrie, Alison M., Clarke, Ed, Imoukhuede, Egeruan B., Ewer, Katie J., Hill, Adrian V. S., Afolabi, Muhammed O.
Publicado 2017

A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults

por Minassian, Angela M, Rowland, Rosalind, Beveridge, Natalie E R, Poulton, Ian D, Satti, Iman, Harris, Stephanie, Poyntz, Hazel, Hamill, Matthew, Griffiths, Kristin, Sander, Clare R, Ambrozak, David R, Price, David A, Hill, Brenna J, Casazza, Joseph P, Douek, Daniel C, Koup, Richard A, Roederer, Mario, Winston, Alan, Ross, Jonathan, Sherrard, Jackie, Rooney, Guy, Williams, Nicola, Lawrie, Alison M, Fletcher, Helen A, Pathan, Ansar A, McShane, Helen
Publicado 2011

Clinical Assessment of a Recombinant Simian Adenovirus ChAd63: A Potent New Vaccine Vector

por O’Hara, Geraldine A., Duncan, Christopher J. A., Ewer, Katie J., Collins, Katharine A., Elias, Sean C., Halstead, Fenella D., Goodman, Anna L., Edwards, Nick J., Reyes-Sandoval, Arturo, Bird, Prudence, Rowland, Rosalind, Sheehy, Susanne H., Poulton, Ian D., Hutchings, Claire, Todryk, Stephen, Andrews, Laura, Folgori, Antonella, Berrie, Eleanor, Moyle, Sarah, Nicosia, Alfredo, Colloca, Stefano, Cortese, Riccardo, Siani, Loredana, Lawrie, Alison M., Gilbert, Sarah C., Hill, Adrian V. S.
Publicado 2012

Phase Ia Clinical Evaluation of the Safety and Immunogenicity of the Plasmodium falciparum Blood-Stage Antigen AMA1 in ChAd63 and MVA Vaccine Vectors

por Sheehy, Susanne H., Duncan, Christopher J. A., Elias, Sean C., Biswas, Sumi, Collins, Katharine A., O'Hara, Geraldine A., Halstead, Fenella D., Ewer, Katie J., Mahungu, Tabitha, Spencer, Alexandra J., Miura, Kazutoyo, Poulton, Ian D., Dicks, Matthew D. J., Edwards, Nick J., Berrie, Eleanor, Moyle, Sarah, Colloca, Stefano, Cortese, Riccardo, Gantlett, Katherine, Long, Carole A., Lawrie, Alison M., Gilbert, Sarah C., Doherty, Tom, Nicosia, Alfredo, Hill, Adrian V. S., Draper, Simon J.
Publicado 2012

Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial

por de Graaf, Hans, Payne, Ruth O., Taylor, Iona, Miura, Kazutoyo, Long, Carol A., Elias, Sean C., Zaric, Marija, Minassian, Angela M., Silk, Sarah E., Li, Lee, Poulton, Ian D., Baker, Megan, Draper, Simon J., Gbesemete, Diane, Brendish, Nathan J., Martins, Filipa, Marini, Arianna, Mekhaiel, David, Edwards, Nick J., Roberts, Rachel, Vekemans, Johan, Moyle, Sarah, Faust, Saul N., Berrie, Eleanor, Lawrie, Alison M., Hill, Fergal, Hill, Adrian V. S., Biswas, Sumi
Publicado 2021

Protective CD8(+) T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

por Ewer, Katie J., O’Hara, Geraldine A., Duncan, Christopher J. A., Collins, Katharine A., Sheehy, Susanne H., Reyes-Sandoval, Arturo, Goodman, Anna L., Edwards, Nick J., Elias, Sean C., Halstead, Fenella D., Longley, Rhea J., Rowland, Rosalind, Poulton, Ian D., Draper, Simon J., Blagborough, Andrew M., Berrie, Eleanor, Moyle, Sarah, Williams, Nicola, Siani, Loredana, Folgori, Antonella, Colloca, Stefano, Sinden, Robert E., Lawrie, Alison M., Cortese, Riccardo, Gilbert, Sarah C., Nicosia, Alfredo, Hill, Adrian V. S.
Publicado 2013

Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals

por Hodgson, Susanne H., Ewer, Katie J., Bliss, Carly M., Edwards, Nick J., Rampling, Thomas, Anagnostou, Nicholas A., de Barra, Eoghan, Havelock, Tom, Bowyer, Georgina, Poulton, Ian D., de Cassan, Simone, Longley, Rhea, Illingworth, Joseph J., Douglas, Alexander D., Mange, Pooja B., Collins, Katharine A., Roberts, Rachel, Gerry, Stephen, Berrie, Eleanor, Moyle, Sarah, Colloca, Stefano, Cortese, Riccardo, Sinden, Robert E., Gilbert, Sarah C., Bejon, Philip, Lawrie, Alison M., Nicosia, Alfredo, Faust, Saul N., Hill, Adrian V. S.
Publicado 2015

Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: Safety and parasite growth dynamics

por Salkeld, Jo, Themistocleous, Yrene, Barrett, Jordan R., Mitton, Celia H., Rawlinson, Thomas A., Payne, Ruth O., Hou, Mimi M., Khozoee, Baktash, Edwards, Nick J., Nielsen, Carolyn M., Sandoval, Diana Muñoz, Bach, Florian A., Nahrendorf, Wiebke, Ramon, Raquel Lopez, Baker, Megan, Ramos-Lopez, Fernando, Folegatti, Pedro M., Quinkert, Doris, Ellis, Katherine J., Poulton, Ian D., Lawrie, Alison M., Cho, Jee-Sun, Nugent, Fay L., Spence, Philip J., Silk, Sarah E., Draper, Simon J., Minassian, Angela M.
Publicado 2022

Impact on Malaria Parasite Multiplication Rates in Infected Volunteers of the Protein-in-Adjuvant Vaccine AMA1-C1/Alhydrogel+CPG 7909

por Duncan, Christopher J. A., Sheehy, Susanne H., Ewer, Katie J., Douglas, Alexander D., Collins, Katharine A., Halstead, Fenella D., Elias, Sean C., Lillie, Patrick J., Rausch, Kelly, Aebig, Joan, Miura, Kazutoyo, Edwards, Nick J., Poulton, Ian D., Hunt-Cooke, Angela, Porter, David W., Thompson, Fiona M., Rowland, Ros, Draper, Simon J., Gilbert, Sarah C., Fay, Michael P., Long, Carole A., Zhu, Daming, Wu, Yimin, Martin, Laura B., Anderson, Charles F., Lawrie, Alison M., Hill, Adrian V. S., Ellis, Ruth D.
Publicado 2011

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01(B) With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing M...

por Rampling, Tommy, Ewer, Katie J., Bowyer, Georgina, Bliss, Carly M., Edwards, Nick J., Wright, Danny, Payne, Ruth O., Venkatraman, Navin, de Barra, Eoghan, Snudden, Claudia M., Poulton, Ian D., de Graaf, Hans, Sukhtankar, Priya, Roberts, Rachel, Ivinson, Karen, Weltzin, Rich, Rajkumar, Bebi-Yassin, Wille-Reece, Ulrike, Lee, Cynthia K., Ockenhouse, Christian F., Sinden, Robert E., Gerry, Stephen, Lawrie, Alison M., Vekemans, Johan, Morelle, Danielle, Lievens, Marc, Ballou, Ripley W., Cooke, Graham S., Faust, Saul N., Gilbert, Sarah, Hill, Adrian V. S.
Publicado 2016

Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies

por Payne, Ruth O., Silk, Sarah E., Elias, Sean C., Milne, Kathryn H., Rawlinson, Thomas A., Llewellyn, David, Shakri, A. Rushdi, Jin, Jing, Labbé, Geneviève M., Edwards, Nick J., Poulton, Ian D., Roberts, Rachel, Farid, Ryan, Jørgensen, Thomas, Alanine, Daniel G.W., de Cassan, Simone C., Higgins, Matthew K., Otto, Thomas D., McCarthy, James S., de Jongh, Willem A., Nicosia, Alfredo, Moyle, Sarah, Hill, Adrian V.S., Berrie, Eleanor, Chitnis, Chetan E., Lawrie, Alison M., Draper, Simon J.
Publicado 2017