Effects of psoriasis and psoralen exposure on the somatic mutation landscape of the skin

por Olafsson, Sigurgeir, Rodriguez, Elke, Lawson, Andrew R. J., Abascal, Federico, Huber, Axel Rosendahl, Suembuel, Melike, Jones, Philip H., Gerdes, Sascha, Martincorena, Iñigo, Weidinger, Stephan, Campbell, Peter J., Anderson, Carl A.
Publicado 2023

Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways

por Jones, Tania A., Jeyapalan, Jennie N., Forshew, Tim, Tatevossian, Ruth G., Lawson, Andrew R. J., Patel, Sheena N., Doctor, Gabriel T., Mumin, Muhammad A., Picker, Simon R., Phipps, Kim P., Michalski, Antony, Jacques, Thomas S., Sheer, Denise
Publicado 2015

Increased somatic mutation burdens in normal human cells due to defective DNA polymerases

por Robinson, Philip S., Coorens, Tim H. H., Palles, Claire, Mitchell, Emily, Abascal, Federico, Olafsson, Sigurgeir, Lee, Bernard C. H., Lawson, Andrew R. J., Lee-Six, Henry, Moore, Luiza, Sanders, Mathijs A., Hewinson, James, Martin, Lynn, Pinna, Claudia M. A., Galavotti, Sara, Rahbari, Raheleh, Campbell, Peter J., Martincorena, Iñigo, Tomlinson, Ian, Stratton, Michael R.
Publicado 2021

Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight

por Hurst, Carolyn D., Cheng, Guo, Platt, Fiona M., Castro, Mauro A.A., Marzouka, Nour-al-dain S., Eriksson, Pontus, Black, Emma V.I., Alder, Olivia, Lawson, Andrew R.J., Lindskrog, Sia V., Burns, Julie E., Jain, Sunjay, Roulson, Jo-An, Brown, Joanne C., Koster, Jan, Robertson, A. Gordon, Martincorena, Inigo, Dyrskjøt, Lars, Höglund, Mattias, Knowles, Margaret A.
Publicado 2021

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA

por Gale, Davina, Lawson, Andrew R. J., Howarth, Karen, Madi, Mikidache, Durham, Bradley, Smalley, Sarah, Calaway, John, Blais, Shannon, Jones, Greg, Clark, James, Dimitrov, Peter, Pugh, Michelle, Woodhouse, Samuel, Epstein, Michael, Fernandez-Gonzalez, Ana, Whale, Alexandra S., Huggett, Jim F., Foy, Carole A., Jones, Gerwyn M., Raveh-Amit, Hadas, Schmitt, Karin, Devonshire, Alison, Green, Emma, Forshew, Tim, Plagnol, Vincent, Rosenfeld, Nitzan
Publicado 2018

Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer

por Li, Ruoyan, Ferdinand, John R., Loudon, Kevin W., Bowyer, Georgina S., Laidlaw, Sean, Muyas, Francesc, Mamanova, Lira, Neves, Joana B., Bolt, Liam, Fasouli, Eirini S., Lawson, Andrew R.J., Young, Matthew D., Hooks, Yvette, Oliver, Thomas R.W., Butler, Timothy M., Armitage, James N., Aho, Tev, Riddick, Antony C.P., Gnanapragasam, Vincent, Welsh, Sarah J., Meyer, Kerstin B., Warren, Anne Y., Tran, Maxine G.B., Stewart, Grant D., Cortés-Ciriano, Isidro, Behjati, Sam, Clatworthy, Menna R., Campbell, Peter J., Teichmann, Sarah A., Mitchell, Thomas J.
Publicado 2022

Somatic mutation rates scale with lifespan across mammals

por Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim H. H., Sanders, Mathijs A., Lawson, Andrew R. J., Harvey, Luke M. R., Bhosle, Shriram, Jones, David, Alcantara, Raul E., Butler, Timothy M., Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W., Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D., Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan St. John, Gerstung, Moritz, Campbell, Peter J., Murchison, Elizabeth P., Stratton, Michael R., Martincorena, Iñigo
Publicado 2022