CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas

por Chen, Linfeng, Ouyang, Jing, Wienand, Kirsty, Bojarczuk, Kamil, Hao, Yansheng, Chapuy, Bjoern, Neuberg, Donna, Juszczynski, Przemyslaw, Lawton, Lee N., Rodig, Scott J., Monti, Stefano, Shipp, Margaret A.
Publicado 2020

A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth

por Meacham, Corbin E., Lawton, Lee N., Soto-Feliciano, Yadira M., Pritchard, Justin R., Joughin, Brian A., Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T., Young, Richard A., Hemann, Michael T.
Publicado 2015

ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis

por Leong, Wei Zhong, Tan, Shi Hao, Ngoc, Phuong Cao Thi, Amanda, Stella, Yam, Alice Wei Yee, Liau, Wei-Siang, Gong, Zhiyuan, Lawton, Lee N., Tenen, Daniel G., Sanda, Takaomi
Publicado 2017

T028: Single-cell RNA sequencing reveals the interplay between circulating CD4 T cells, B cells and cancer-associated monocytes in classic Hodgkin lymphoma treated with PD-1 blocka...

por Paczkowska, Julia, Tang, Ming, Wright, Kyle T., Song, Li, Shanmugam, Vignesh, Luu, Kelsey, Welsh, Emma L., Cader, Fathima Zumla, Mandato, Elisa, Ouyang, Jing, Bai, Gali, Lawton, Lee, Rodig, Scott, Liu, X Shirley, Shipp, Margaret A.
Publicado 2022

The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia

por Mansour, Marc R., Sanda, Takaomi, Lawton, Lee N., Li, Xiaoyu, Kreslavsky, Taras, Novina, Carl D., Brand, Marjorie, Gutierrez, Alejandro, Kelliher, Michelle A., Jamieson, Catriona H.M., von Boehmer, Harald, Young, Richard A., Look, A. Thomas
Publicado 2013

ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry

por Wang, Lu, Tan, Tze King, Durbin, Adam D., Zimmerman, Mark W., Abraham, Brian J., Tan, Shi Hao, Ngoc, Phuong Cao Thi, Weichert-Leahey, Nina, Akahane, Koshi, Lawton, Lee N., Rokita, Jo Lynne, Maris, John M., Young, Richard A., Look, A. Thomas, Sanda, Takaomi
Publicado 2019