The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway

por Mattoon, Dawn R, Lamothe, Betty, Lax, Irit, Schlessinger, Joseph
Publicado 2004

Heparin is essential for optimal cell signaling by FGF21 and for regulation of βKlotho cellular stability

por An, Seong J., Mohanty, Jyotidarsini, Tome, Francisco, Suzuki, Yoshihisa, Lax, Irit, Schlessinger, Joseph
Publicado 2023

FRS2α Regulates Erk Levels to Control a Self-Renewal Target Hes1 and Proliferation of FGF-Responsive Neural Stem/Progenitor Cells

por Sato, Takuya, Shimazaki, Takuya, Naka, Hayato, Fukami, Shin-Ichi, Satoh, Yasushi, Okano, Hideyuki, Lax, Irit, Schlessinger, Joseph, Gotoh, Noriko
Publicado 2010

Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities

por Lew, Erin D, Oh, Jennifer, Burrola, Patrick G, Lax, Irit, Zagórska, Anna, Través, Paqui G, Schlessinger, Joseph, Lemke, Greg
Publicado 2014

Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention

por Krimmer, Stefan G., Bertoletti, Nicole, Suzuki, Yoshihisa, Katic, Luka, Mohanty, Jyotidarsini, Shu, Sheng, Lee, Sangwon, Lax, Irit, Mi, Wei, Schlessinger, Joseph
Publicado 2023