Does FFAR4 Agonism have Therapeutic Potential in Cardiometabolic Disease?

por Lay, Abigail C
Publicado 2021

The Evolving Importance of Insulin Signaling in Podocyte Health and Disease

por Lay, Abigail C., Coward, Richard J. M.
Publicado 2018

Podocyte Bioenergetics in the Development of Diabetic Nephropathy: The Role of Mitochondria

por Audzeyenka, Irena, Bierżyńska, Agnieszka, Lay, Abigail C
Publicado 2021

Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function

por Hurcombe, Jennifer A., Lay, Abigail C., Ni, Lan, Barrington, Alexandra F., Woodgett, Jim R., Quaggin, Susan E., Welsh, Gavin I., Coward, Richard J.
Publicado 2019

An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles

por Barreiro, Karina, Lay, Abigail C., Leparc, German, Tran, Van Du T., Rosler, Marcel, Dayalan, Lusyan, Burdet, Frederic, Ibberson, Mark, Coward, Richard J. M., Huber, Tobias B., Krämer, Bernhard K., Delic, Denis, Holthofer, Harry
Publicado 2023

Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor

por Lay, Abigail C., Hurcombe, Jenny A., Betin, Virginie M. S., Barrington, Fern, Rollason, Ruth, Ni, Lan, Gillam, Lawrence, Pearson, Grace M. E., Østergaard, Mette V., Hamidi, Hellyeh, Lennon, Rachel, Welsh, Gavin I., Coward, Richard J. M.
Publicado 2017

Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease

por Ramnath, Raina D., Butler, Matthew J., Newman, Georgina, Desideri, Sara, Russell, Amy, Lay, Abigail C., Neal, Chris R., Qiu, Yan, Fawaz, Sarah, Onions, Karen L., Gamez, Monica, Crompton, Michael, Michie, Chris, Finch, Natalie, Coward, Richard J., Welsh, Gavin I., Foster, Rebecca R., Satchell, Simon C.
Publicado 2020

IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes

por Lay, Abigail C., Hale, Lorna J., Stowell-Connolly, Holly, Pope, Robert J. P., Nair, Viji, Ju, Wenjun, Marquez, Eva, Rollason, Ruth, Hurcombe, Jenny A., Hayes, Bryony, Roberts, Timothy, Gillam, Lawrence, Allington, Jonathan, Nelson, Robert G., Kretzler, Matthias, Holly, Jeff M. P., Perks, Claire M., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.
Publicado 2021

The EWAS Catalog: a database of epigenome-wide association studies

por Battram, Thomas, Yousefi, Paul, Crawford, Gemma, Prince, Claire, Sheikhali Babaei, Mahsa, Sharp, Gemma, Hatcher, Charlie, Vega-Salas, María Jesús, Khodabakhsh, Sahar, Whitehurst, Oliver, Langdon, Ryan, Mahoney, Luke, Elliott, Hannah R., Mancano, Giulia, Lee, Matthew A., Watkins, Sarah H., Lay, Abigail C., Hemani, Gibran, Gaunt, Tom R., Relton, Caroline L., Staley, James R., Suderman, Matthew
Publicado 2022

A role for NPY-NPY2R signaling in albuminuric kidney disease

por Lay, Abigail C., Barrington, A. Fern, Hurcombe, Jenny A., Ramnath, Raina D., Graham, Mark, Lewis, Philip A., Wilson, Marieangela C., Heesom, Kate J., Butler, Matthew J., Perrett, Rebecca M., Neal, Chris R., Herbert, Eleanor, Mountjoy, Edward, Atan, Denize, Nair, Viji, Ju, Wenjun, Nelson, Robert G., Kretzler, Matthias, Satchell, Simon C., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.
Publicado 2020