What to Expect When You’re Expecting Zika

por Lazear, Helen M.
Publicado 2017

Antiviral Effector RTP4 Bats against Flaviviruses

por Nielsen, Joshua R., Lazear, Helen M.
Publicado 2020

Interferon-λ: Immune Functions at Barrier Surfaces and Beyond

por Lazear, Helen M., Nice, Timothy J., Diamond, Michael S.
Publicado 2015

Interferon Lambda Signals in Maternal Tissues to Exert Protective and Pathogenic Effects in a Gestational Stage-Dependent Manner

por Casazza, Rebecca L., Philip, Drake T., Lazear, Helen M.
Publicado 2022

Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus Infection

por Sheehan, Kathleen C. F., Lazear, Helen M., Diamond, Michael S., Schreiber, Robert D.
Publicado 2015

Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8(+) T Cell Immune Responses against West Nile Virus Infection

por Brien, James D., Daffis, Stephane, Lazear, Helen M., Cho, Hyelim, Suthar, Mehul S., Gale, Michael, Diamond, Michael S.
Publicado 2011

Role of Caspases and Gasdermin A during HSV-1 Infection in Mice

por Li, Lupeng, Kovacs, Stephen B., Jørgensen, Ine, Larson, Heather N., Lazear, Helen M., Miao, Edward A.
Publicado 2022

Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology

por Philip, Drake T., Goins, Nigel M., Catanzaro, Nicholas J., Misumi, Ichiro, Whitmire, Jason K., Atkins, Hannah M., Lazear, Helen M.
Publicado 2023

Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection

por Collins, Matthew H., McGowan, Eileen, Jadi, Ramesh, Young, Ellen, Lopez, Cesar A., Baric, Ralph S., Lazear, Helen M., de Silva, Aravinda M.
Publicado 2017

Oligomeric state of the ZIKV E protein defines protective immune responses

por Metz, Stefan W., Thomas, Ashlie, Brackbill, Alex, Forsberg, John, Miley, Michael J., Lopez, Cesar A., Lazear, Helen M., Tian, Shaomin, de Silva, Aravinda M.
Publicado 2019

The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity

por Miner, Jonathan J., Daniels, Brian P., Shrestha, Bimmi, Proenca-Modena, Jose L., Lew, Erin D., Lazear, Helen M., Gorman, Matthew J., Lemke, Greg, Klein, Robyn S., Diamond, Michael S.
Publicado 2015

A Reverse Genetics Platform That Spans the Zika Virus Family Tree

por Widman, Douglas G., Young, Ellen, Yount, Boyd L., Plante, Kenneth S., Gallichotte, Emily N., Carbaugh, Derek L., Peck, Kayla M., Plante, Jessica, Swanstrom, Jesica, Heise, Mark T., Lazear, Helen M., Baric, Ralph S.
Publicado 2017

Lifetime of ground conformational state determines the activity of structured RNA

por Thompson, Rhese D., Carbaugh, Derek L., Nielsen, Joshua R., Witt, Ciara M., Meganck, Rita M., Rangadurai, Atul, Zhao, Bo, Bonin, Jeffrey P., Nicely, Nathan I., Marzluff, William F., Frank, Aaron T., Lazear, Helen M., Zhang, Qi
Publicado 2023

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

por Lazear, Helen M., Lancaster, Alissa, Wilkins, Courtney, Suthar, Mehul S., Huang, Albert, Vick, Sarah C., Clepper, Lisa, Thackray, Larissa, Brassil, Margaret M., Virgin, Herbert W., Nikolich-Zugich, Janko, Moses, Ashlee V., Gale, Michael, Früh, Klaus, Diamond, Michael S.
Publicado 2013

Correction: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

por Lazear, Helen M., Lancaster, Alissa, Wilkins, Courtney, Suthar, Mehul S., Huang, Albert, Vick, Sarah C., Clepper, Lisa, Thackray, Larissa, Brassil, Margaret M., Virgin, Herbert W., Nikolich-Zugich, Janko, Moses, Ashlee V., Gale, Michael, Früh, Klaus, Diamond, Michael S.
Publicado 2013

Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus

por Adams, Cameron, Carbaugh, Derek L., Shu, Bo, Ng, Thiam-Seng, Castillo, Izabella N., Bhowmik, Ryan, Segovia-Chumbez, Bruno, Puhl, Ana C., Graham, Stephen, Diehl, Sean A., Lazear, Helen M., Lok, Shee-mei, de Silva, Aravinda M., Premkumar, Lakshmanane
Publicado 2023

IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection

por Kwock, Jeffery T., Handfield, Chelsea, Suwanpradid, Jutamas, Hoang, Peter, McFadden, Michael J., Labagnara, Kevin F., Floyd, Lauren, Shannon, Jessica, Uppala, Ranjitha, Sarkar, Mrinal K., Gudjonsson, Johann E., Corcoran, David L., Lazear, Helen M., Sempowski, Gregory, Horner, Stacy M., MacLeod, Amanda S.
Publicado 2020

Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy

por Singh, Tulika, Lopez, Cesar A., Giuberti, Camila, Dennis, Maria L., Itell, Hannah L., Heimsath, Holly J., Webster, Helen S., Roark, Hunter K., Merçon de Vargas, Paulo R., Hall, Allison, Corey, Ralph G., Swamy, Geeta K., Dietze, Reynaldo, Lazear, Helen M., Permar, Sallie R.
Publicado 2019

COVID-19 and emerging viral infections: The case for interferon lambda

por Prokunina-Olsson, Ludmila, Alphonse, Noémie, Dickenson, Ruth E., Durbin, Joan E., Glenn, Jeffrey S., Hartmann, Rune, Kotenko, Sergei V., Lazear, Helen M., O’Brien, Thomas R., Odendall, Charlotte, Onabajo, Olusegun O., Piontkivska, Helen, Santer, Deanna M., Reich, Nancy C., Wack, Andreas, Zanoni, Ivan
Publicado 2020

K63-linked polyubiquitylation of IRF1 transcription factor is essential for IL-1-induced CCL5 and CXCL10 chemokine production

por Harikumar, Kuzhuvelil B., Yester, Jessie W., Surace, Michael J., Oyeniran, Clement, Price, Megan M., Huang, Wei-Ching, Hait, Nitai C., Allegood, Jeremy C., Yamada, Akimitsu, Kong, Xiangqian, Lazear, Helen M., Bhardwaj, Reetika, Takabe, Kazuaki, Diamond, Michael S., Luo, Cheng, Milstien, Sheldon, Spiegel, Sarah, Kordula, Tomasz
Publicado 2014