Efficient correction of a deleterious point mutation in primary horse fibroblasts with CRISPR-Cas9

por Pinzon-Arteaga, Carlos, Snyder, Matthew D., Lazzarotto, Cicera R., Moreno, Nicolas F., Juras, Rytis, Raudsepp, Terje, Golding, Michael C., Varner, Dickson D., Long, Charles R.
Publicado 2020

Susceptibility of Mice to Trypanosoma evansi Treated with Human Plasma Containing Different Concentrations of Apolipoprotein L-1

por Da Silva, Aleksandro S., Fanfa, Vinicius R., Otto, Mateus A., Gressler, Lucas T., Tavares, Kaio C.S., Lazzarotto, Cícera R., Tonin, Alexandre A., Miletti, Luiz C., Duarte, Marta M.M.F., Monteiro, Silvia G.
Publicado 2011

Base editing as a genetic treatment for spinal muscular atrophy

por Alves, Christiano R. R., Ha, Leillani L., Yaworski, Rebecca, Lazzarotto, Cicera R., Christie, Kathleen A., Reilly, Aoife, Beauvais, Ariane, Doll, Roman M., de la Cruz, Demitri, Maguire, Casey A., Swoboda, Kathryn J., Tsai, Shengdar Q., Kothary, Rashmi, Kleinstiver, Benjamin P.
Publicado 2023

CHANGE-seq reveals genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity

por Lazzarotto, Cicera R., Malinin, Nikolay L., Li, Yichao, Zhang, Ruochi, Yang, Yang, Lee, GaHyun, Cowley, Eleanor, He, Yanghua, Lan, Xin, Jividen, Kasey, Katta, Varun, Kolmakova, Natalia G., Petersen, Christopher T., Qi, Qian, Strelcov, Evgheni, Maragh, Samantha, Krenciute, Giedre, Ma, Jian, Cheng, Yong, Tsai, Shengdar Q.
Publicado 2020

Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression

por Mueller, Katherine P, Piscopo, Nicole J, Forsberg, Matthew H, Saraspe, Louise A, Das, Amritava, Russell, Brittany, Smerchansky, Madeline, Cappabianca, Dan, Shi, Lei, Shankar, Keerthana, Sarko, Lauren, Khajanchi, Namita, La Vonne Denne, Nina, Ramamurthy, Apoorva, Ali, Adeela, Lazzarotto, Cicera R, Tsai, Shengdar Q, Capitini, Christian M, Saha, Krishanu
Publicado 2022

Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression

por Gao, Pan, Lyu, Qing, Ghanam, Amr R., Lazzarotto, Cicera R., Newby, Gregory A., Zhang, Wei, Choi, Mihyun, Slivano, Orazio J., Holden, Kevin, Walker, John A., Kadina, Anastasia P., Munroe, Rob J., Abratte, Christian M., Schimenti, John C., Liu, David R., Tsai, Shengdar Q., Long, Xiaochun, Miano, Joseph M.
Publicado 2021

CRISPR-Cas9-AAV versus lentivector transduction for genome modification of X-linked severe combined immunodeficiency hematopoietic stem cells

por Brault, Julie, Liu, Taylor, Liu, Siyuan, Lawson, Amanda, Choi, Uimook, Kozhushko, Nikita, Bzhilyanskaya, Vera, Pavel-Dinu, Mara, Meis, Ronald J., Eckhaus, Michael A., Burkett, Sandra S., Bosticardo, Marita, Kleinstiver, Benjamin P., Notarangelo, Luigi D., Lazzarotto, Cicera R., Tsai, Shengdar Q., Wu, Xiaolin, Dahl, Gary A., Porteus, Matthew H., Malech, Harry L., De Ravin, Suk See
Publicado 2023

Highly efficient therapeutic gene editing of human hematopoietic stem cells

por Wu, Yuxuan, Zeng, Jing, Roscoe, Benjamin P., Liu, Pengpeng, Yao, Qiuming, Lazzarotto, Cicera R., Clement, M. Kendell, Cole, Mitchel A., Luk, Kevin, Baricordi, Cristina, Shen, Anne H., Ren, Chunyan, Esrick, Erica B., Manis, John P., Dorfman, David M., Williams, David A., Biffi, Alessandra, Brugnara, Carlo, Biasco, Luca, Brendel, Christian, Pinello, Luca, Tsai, Shengdar Q., Wolfe, Scot A., Bauer, Daniel E.
Publicado 2019