Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer Ladder

por Le Grice, Stuart F. J.
Publicado 2015

Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis

por Rausch, Jason W., Le Grice, Stuart F. J.
Publicado 2007

Probing Retroviral and Retrotransposon Genome Structures: The “SHAPE” of Things to Come

por Sztuba-Solinska, Joanna, Le Grice, Stuart F. J.
Publicado 2012

HIV Rev Assembly on the Rev Response Element (RRE): A Structural Perspective

por Rausch, Jason W., Le Grice, Stuart F. J.
Publicado 2015

Characterizing the Latent HIV-1 Reservoir in Patients with Viremia Suppressed on cART: Progress, Challenges, and Opportunities

por Rausch, Jason W., Le Grice, Stuart F.J.
Publicado 2020

Revisiting Plus-Strand DNA Synthesis in Retroviruses and Long Terminal Repeat Retrotransposons: Dynamics of Enzyme: Substrate Interactions

por Fabris, Daniele, Marino, John P., Le Grice, Stuart F.J.
Publicado 2009

Reverse Transcription in the Saccharomyces cerevisiae Long-Terminal Repeat Retrotransposon Ty3

por Rausch, Jason W., Miller, Jennifer T., Le Grice, Stuart F. J.
Publicado 2017

Determinants of Genomic RNA Encapsidation in the Saccharomyces cerevisiae Long Terminal Repeat Retrotransposons Ty1 and Ty3

por Pachulska-Wieczorek, Katarzyna, Le Grice, Stuart F.J., Purzycka, Katarzyna J.
Publicado 2016

Probing the Structures of Viral RNA Regulatory Elements with SHAPE and Related Methodologies

por Rausch, Jason W., Sztuba-Solinska, Joanna, Le Grice, Stuart F. J.
Publicado 2018

Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function

por Mandal, Dibyakanti, Dash, Chandravanu, Le Grice, Stuart F. J., Prasad, Vinayaka R.
Publicado 2006

DNA binding proteins explore multiple local configurations during docking via rapid rebinding

por Ganji, Mahipal, Docter, Margreet, Le Grice, Stuart F.J., Abbondanzieri, Elio A.
Publicado 2016

Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase

por Bibillo, Arkadiusz, Lener, Daniela, Klarmann, George J., Le Grice, Stuart F. J.
Publicado 2005

Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription

por Liu, Shixin, Harada, Bryan T., Miller, Jennifer T., Le Grice, Stuart F. J., Zhuang, Xiaowei
Publicado 2010

Complexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradation

por Lapkouski, Mikalai, Tian, Lan, Miller, Jennifer T., Le Grice, Stuart F. J., Yang, Wei
Publicado 2013

Examining the ribonuclease H primer grip of HIV-1 reverse transcriptase by charge neutralization of RNA/DNA hybrids

por Dash, Chandravanu, Scarth, Brian J., Badorrek, Christopher, Götte, Matthias, Le Grice, Stuart F. J.
Publicado 2008

Viral Reverse Transcriptases Show Selective High Affinity Binding to DNA-DNA Primer-Templates that Resemble the Polypurine Tract

por Nair, Gauri R., Dash, Chandravanu, Le Grice, Stuart F. J., DeStefano, Jeffrey J.
Publicado 2012

Influence of RNA structural elements on Ty1 retrotransposition

por Purzycka, Katarzyna J., Garfinkel, David J., Boeke, Jef D., Le Grice, Stuart F.J.
Publicado 2013

The “complex” RNA post-transcriptional element of a “simple” retrovirus

por Purzycka, Katarzyna J, Pilkington, Guy R, Felber, Barbara K, Le Grice, Stuart F J
Publicado 2015

In-gel probing of individual RNA conformers within a mixed population reveals a dimerization structural switch in the HIV-1 leader

por Kenyon, Julia C., Prestwood, Liam J., Le Grice, Stuart F. J., Lever, Andrew M. L.
Publicado 2013

The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication

por Sherpa, Chringma, Rausch, Jason W., Le Grice, Stuart F.J., Hammarskjold, Marie-Louise, Rekosh, David
Publicado 2015